Results 91 to 100 of about 43,769 (228)

Rilzabrutinib for the Treatment of Immune Thrombocytopenia

open access: yesEuropean Journal of Haematology, Volume 115, Issue 1, Page 4-15, July 2025.
ABSTRACT Advancements in the understanding of ITP pathogenesis have led to significant improvements in disease management through the use of both traditional immunosuppressive strategies and novel targeted therapies. However, a subset of patients remains refractory to treatment or achieves only transient benefits, underscoring the need for alternative ...
Caterina Labanca   +12 more
wiley   +1 more source

Inhibition of sialidase activity as a therapeutic approach

open access: yesDrug Design, Development and Therapy, 2018
Victor Yu Glanz,1 Veronika A Myasoedova,2 Andrey V Grechko,3 Alexander N Orekhov2,4 1Department of Genetics, Cytology and Bioengineering, Faculty of Biology and Medicine, Voronezh State University, Voronezh, Russia; 2Laboratory of Angiopathology ...
Glanz VY   +3 more
doaj  

Genetic Evolution of the Hemagglutinin Genes of Seasonal Influenza A Viruses in Türkiye Between 2017 and 2023

open access: yesInfluenza and Other Respiratory Viruses, Volume 19, Issue 7, July 2025.
ABSTRACT Background Seasonal influenza A viruses (IAVs) remain a major global health concern, causing up to 650,000 deaths annually. Over the past century, four influenza pandemics have occurred, with H3N2 and H1N1 subtypes becoming endemic in humans.
M. Ekin Azbazdar   +3 more
wiley   +1 more source

Influenza Type B Neuraminidase Can Replace the Function of Type A Neuraminidase

open access: yesVirology, 1999
Influenza A and B viruses do not form reassortants with each other, presumably due to selection at either the RNA or protein level. Although differences in the promoter sequences of type A and B viruses have been studied, selection at the protein level has not been addressed.
Anita A. Ghate, Gillian M. Air
openaire   +3 more sources

Action of influenza virus neuraminidase on gangliosides

open access: yesFEBS Letters, 1985
The action of partly purified neuraminidase (NA) of influenza A virus, a mixture of detergent solubilized NA and haemagglutinin (HA) and of intact virions on gangliosides GTlb, gdla, GDlb, gml was studied. The viral NA transformed gtlb mainly into GDlbWith formation of only minor amounts of GMl.
J.I. Shaposhnikova   +6 more
openaire   +3 more sources

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