RTEL1 gene polymorphisms and neuroblastoma risk in Chinese children
Background Neuroblastoma, a neuroendocrine tumor originating from the sympathetic ganglia, is one of the most common malignancies in childhood. RTEL1 is critical in many fundamental cellular processes, such as DNA replication, DNA damage repair, genomic ...
Ting Zhang +5 more
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Influence of surgical excision on the survival of patients with stage 4 high-risk neuroblastoma : a report from the HR-NBL1/SIOPEN study [PDF]
PURPOSE To evaluate the impact of surgeon-assessed extent of primary tumor resection on local progression and survival in patients in the International Society of Pediatric Oncology Europe Neuroblastoma Group High-Risk Neuroblastoma 1 trial. PATIENTS AND
Metzelder, Martin +137 more
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EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth.
Investigation of the mechanisms responsible for aggressive neuroblastoma and its poor prognosis is critical to identify novel therapeutic targets and improve survival.
Laura V Bownes +11 more
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Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy [PDF]
Background: The treatment of high-risk neuroblastoma patients consists of multimodal induction therapy to achieve remission followed by consolidation therapy to prevent relapses. However, the type of consolidation therapy is still discussed controversial.
Berthold, Frank +20 more
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Selection of a highly invasive neuroblastoma cell population through long-term human cytomegalovirus infection. [PDF]
The human cytomegalovirus (HCMV) is suspected to increase tumour malignancy by infection of cancer and/or stroma cells (oncomodulation). So far, oncomodulatory mechanisms have been attributed to the presence of HCMV and direct action of its gene products
Steinberger, D. +30 more
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Anesthetic management of an infant with giant abdominal neuroblastoma
Neuroblastoma is the most common, non-central nervous system tumor of childhood. It has the potential to synthesize catecholamines. However, the presences of hypertension are uncommon.
Manuel Ángel Gómez-Ríos +2 more
doaj +1 more source
Background Neuroblastoma is a pediatric tumor of neural crest cells that is clinically characterized by its variable evolution, from spontaneous regression to malignancy.
Gingras Denis +5 more
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On the cytotoxicity of HCR-NTPase in the neuroblastoma cell line SH-SY5Y [PDF]
Pasdziernik M, Kaltschmidt B, Kaltschmidt C, Klinger C, Kaufmann M. On the cytotoxicity of HCR-NTPase in the neuroblastoma cell line SH-SY5Y. BMC Research Notes. 2009;2(1):102.Background: The human cancer-related nucleoside triphosphatase (HCR-NTPase) is
Klinger, Claudia +9 more
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A Neuroblastoma Case Presenting with Seizures Resistant to Anti-Epileptic Treatments [PDF]
Seizure is a rare symptom of paraneoplastic syndrome seen in neuroblastoma without a previous history. A 4-month-old male patient who was followed up with a preliminary diagnosis of an adrenal mass in pediatric oncology was admitted to hospital with a ...
Sibğatullah Ali Orak +15 more
core +1 more source
Neuroblastoma is a childhood malignancy and in the majority of patients, the primary tumor arises in one of the adrenal glands. Neuroblastoma cells highly express the disialoganglioside GD2, which is the primary target for the development of ...
Renske J. E. van den Bijgaart +7 more
doaj +1 more source

