Results 21 to 30 of about 185,865 (259)

RTEL1 gene polymorphisms and neuroblastoma risk in Chinese children

open access: yesBMC Cancer, 2023
Background Neuroblastoma, a neuroendocrine tumor originating from the sympathetic ganglia, is one of the most common malignancies in childhood. RTEL1 is critical in many fundamental cellular processes, such as DNA replication, DNA damage repair, genomic ...
Ting Zhang   +5 more
doaj   +1 more source

Influence of surgical excision on the survival of patients with stage 4 high-risk neuroblastoma : a report from the HR-NBL1/SIOPEN study [PDF]

open access: yes, 2020
PURPOSE To evaluate the impact of surgeon-assessed extent of primary tumor resection on local progression and survival in patients in the International Society of Pediatric Oncology Europe Neuroblastoma Group High-Risk Neuroblastoma 1 trial. PATIENTS AND
Metzelder, Martin   +137 more
core   +1 more source

EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth.

open access: yesPLoS ONE, 2021
Investigation of the mechanisms responsible for aggressive neuroblastoma and its poor prognosis is critical to identify novel therapeutic targets and improve survival.
Laura V Bownes   +11 more
doaj   +1 more source

Long term outcome of high-risk neuroblastoma patients after immunotherapy with antibody ch14.18 or oral metronomic chemotherapy [PDF]

open access: yes, 2011
Background: The treatment of high-risk neuroblastoma patients consists of multimodal induction therapy to achieve remission followed by consolidation therapy to prevent relapses. However, the type of consolidation therapy is still discussed controversial.
Berthold, Frank   +20 more
core   +2 more sources

Selection of a highly invasive neuroblastoma cell population through long-term human cytomegalovirus infection. [PDF]

open access: yes, 2012
The human cytomegalovirus (HCMV) is suspected to increase tumour malignancy by infection of cancer and/or stroma cells (oncomodulation). So far, oncomodulatory mechanisms have been attributed to the presence of HCMV and direct action of its gene products
Steinberger, D.   +30 more
core   +1 more source

Anesthetic management of an infant with giant abdominal neuroblastoma

open access: yesBrazilian Journal of Anesthesiology, 2017
Neuroblastoma is the most common, non-central nervous system tumor of childhood. It has the potential to synthesize catecholamines. However, the presences of hypertension are uncommon.
Manuel Ángel Gómez-Ríos   +2 more
doaj   +1 more source

Identification of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation in association with neuroblastoma progression

open access: yesBMC Cancer, 2009
Background Neuroblastoma is a pediatric tumor of neural crest cells that is clinically characterized by its variable evolution, from spontaneous regression to malignancy.
Gingras Denis   +5 more
doaj   +1 more source

On the cytotoxicity of HCR-NTPase in the neuroblastoma cell line SH-SY5Y [PDF]

open access: yes, 2009
Pasdziernik M, Kaltschmidt B, Kaltschmidt C, Klinger C, Kaufmann M. On the cytotoxicity of HCR-NTPase in the neuroblastoma cell line SH-SY5Y. BMC Research Notes. 2009;2(1):102.Background: The human cancer-related nucleoside triphosphatase (HCR-NTPase) is
Klinger, Claudia   +9 more
core   +1 more source

A Neuroblastoma Case Presenting with Seizures Resistant to Anti-Epileptic Treatments [PDF]

open access: yes, 2022
Seizure is a rare symptom of paraneoplastic syndrome seen in neuroblastoma without a previous history. A 4-month-old male patient who was followed up with a preliminary diagnosis of an adrenal mass in pediatric oncology was admitted to hospital with a ...
Sibğatullah Ali Orak   +15 more
core   +1 more source

Anti-GD2 antibody and Vorinostat immunocombination therapy is highly effective in an aggressive orthotopic neuroblastoma model

open access: yesOncoImmunology, 2020
Neuroblastoma is a childhood malignancy and in the majority of patients, the primary tumor arises in one of the adrenal glands. Neuroblastoma cells highly express the disialoganglioside GD2, which is the primary target for the development of ...
Renske J. E. van den Bijgaart   +7 more
doaj   +1 more source

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