Results 11 to 20 of about 271,126 (314)
Beyond the Primary Infarction: Focus on Mechanisms Related to Secondary Neurodegeneration after Stroke [PDF]
, 2022 Recently, a growing body of evidence has indicated that secondary neurodegeneration after stroke occurs at remote regions of the brain that are connected to the primary infarction site [...
Lin Kooi Ong, Ong, Lin Kooi
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Ecstasy and neurodegeneration [PDF]
BMJ, 1996 Publicity in the popular press and medical journals1 on the dangers of using ecstasy (3,4-methylenedioxymethamphetamine) has concentrated almost exclusively on the problems of acute toxicity. While the unnecessary death of any young person is rightly deplored, it is strange that so little attention is being paid to the long term effects of this ...
A R, Green, G M, Goodwin
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Mitochondria and Neurodegeneration
Bioscience Reports, 2007 Many lines of evidence suggest that mitochondria have a central role in ageing-related neurodegenerative diseases. However, despite the evidence of morphological, biochemical and molecular abnormalities in mitochondria in various tissues of patients with neurodegenerative disorders, the question “is mitochondrial dysfunction a necessary step in ...
PETROZZI, LUCIA +4 more
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Association of tear fluid amyloid and tau levels with disease severity and neurodegeneration
, 2021 There has been increasing interest in finding non-invasive biomarkers for neurodegenerative diseases such as Alzheimer’s disease (AD). This observational study investigated AD-specific biomarkers in tear fluid. Tear fluid was collected from a total of 65
Gijs, Marlies +7 more
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Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration [PDF]
, 2013 Microglia, the resident immune cells of the central nervous system (CNS), play an important role in CNS homeostasis during development, adulthood and ageing.
Perry, V. Hugh +3 more
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Heart fatty acid binding protein and Aβ-associated Alzheimer’s neurodegeneration [PDF]
, 2013 Background Epidemiological and molecular findings suggest a relationship between Alzheimer’s disease (AD) and dyslipidemia, although the nature of this association is not well understood ...
McEvoy, LK +23 more
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Nature Communications, 2022 The genome-wide high-resolution chromatin contact of the human retina identifies genetic control of cell-type specific gene expression pattern, missing heritability in retinopathies, and candidate genes/variants for diseases including AMD and glaucoma.
Claire Marchal +6 more
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Metals and Neurodegeneration [PDF]
F1000Research, 2016 Metals play important roles in the human body, maintaining cell structure and regulating gene expression, neurotransmission, and antioxidant response, to name a few. However, excessive metal accumulation in the nervous system may be toxic, inducing oxidative stress, disrupting mitochondrial function, and impairing the activity of numerous enzymes ...
Pan Chen +2 more
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, 2022 Background: Glial fibrillary acidic protein (GFAP) is a promising candidate blood-based biomarker for Alzheimer's disease (AD) diagnosis and prognostication.
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, 2021 While transcripts of neuronal mitochondrial genes are strongly suppressed in central nervous system inflammation, it is unknown whether this results in mitochondrial dysfunction and whether an increase of mitochondrial function can rescue ...
Roth, Vanessa +16 more
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