Results 71 to 80 of about 160,899 (200)

Chemotherapy‐Induced Nausea and Vomiting in Early Breast Cancer Patients Receiving Adjuvant Chemotherapy With Fluorouracil, Epirubicin, Cyclophosphamide Followed by Docetaxel Versus an Anthracycline‐Free Regimen With Docetaxel, Cyclophosphamide—Results From a Randomized Clinical Trial

International Journal of Cancer, Volume 159, Issue 8, Page 1990-2003, 15 October 2026.
Chemotherapy‐induced nausea and vomiting (CINV) remains a significant clinical problem despite modern antiemetics. In particular, antiemetic strategies for emerging cancer therapies lack detailed evaluation. This randomized trial analyzed hourly CINV data for patients with early breast cancer who received either docetaxel plus cyclophosphamide (TC) or ...
Manuel Hörner, Henning Schäffler, Lothar Häberle, Chloë Goossens, Kerstin Pfister, Elena Leinert, Kristina Veselinovic, Sara Y. Brucker, Uwe Köhler, Georg Heinrich, Andreas Schneeweiss, Matthias W. Beckmann, Peter A. Fasching, Wolfgang Janni, Brigitte Rack, Sabine Heublein, Philipp Ziegler   +16 more
wiley   +1 more source

Neurokinin 1/3 Receptor Antagonists for Vasomotor Symptoms in Women with Breast Cancer

healthbook TIMES. Oncology Hematology
Endocrine therapy remains a cornerstone treatment for patients with hormone receptor-positive breast cancer. However, its benefits are often undermined by treatment-related adverse events, including vasomotor symptoms (VMS) such as hot flashes and night ...
Michael Gnant, Marcus Vetter, Petra Stute   +2 more
doaj   +1 more source

Menopausal hormone therapy and comprehensive postmenopausal care in gynecologic cancer survivors: A position paper from the FIGO Committee on Women at Menopausal Age

International Journal of Gynecology &Obstetrics, Volume 174, Issue 3, Page 1151-1171, September 2026.
Abstract Recent advances in cancer screening, diagnosis, and treatment have greatly improved survival rates among women with gynecologic cancers. More survivors now live long enough to experience treatment‐related menopause. Vasomotor symptoms, genitourinary syndrome of menopause, sexual dysfunction, sleep issues, and long‐term risks from estrogen ...
Agnaldo Lopes da Silva‐Filho, Suvarna Khadilkar, Hema Divakar, Chiara Benedetto, Andrea R. Genazzani, Diana Ramos, Elizabete Argale, Enrique Herrera, Martha Hickey   +8 more
wiley   +1 more source

Contribution of Histamine to Nociceptive Behaviors Induced by Intrathecally Administered Cholecystokinin-8

Frontiers in Pharmacology, 2020
The involvement of spinal release of histamine in the nociceptive behaviors induced by cholecystokinin-8 (CCK-8) was investigated in mice. Intrathecal (i.t.) injection of CCK-8 elicited the nociceptive behaviors consisting of biting and licking.
Takafumi Hayashi, Chizuko Watanabe, Soh Katsuyama, Yasuyuki Agatsuma, Damiana Scuteri, Giacinto Bagetta, Tsukasa Sakurada, Shinobu Sakurada   +7 more
doaj   +1 more source

Receptor‐Targeted Antiemetic Strategies in Cats: A Systematic Review and Intervention‐Specific Meta‐Analysis

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Maropitant showed the most consistent controlled evidence for reducing emesis incidence in cats under perioperative or induced‐emesis conditions. Ondansetron may be beneficial in timing‐specific settings, whereas metoclopramide evidence remains insufficient for pooled inference. .
Uğur Ersöz, Çağlar Özkalipci
wiley   +1 more source

A New Generation of Treatments for Itch

Acta Dermato-Venereologica, 2020
For decades, antihistamines have been the mainstay of treatment for chronic pruritus, yet they often only work by making patients drowsy and forgetful of their itch.
Emilie Fowler, Gil Yosipovitch
doaj   +1 more source

Evidence Summary of Pruritus Management in Patients With Atopic Dermatitis: Implications for Nursing Practice

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background To synthesize the most current and relevant evidence regarding pruritus management in patients with atopic dermatitis (AD), and to identify implications for nursing assessment, education, monitoring, and follow‐up. Method An extensive literature search was conducted across multiple databases, including the Cochrane Library, Embase ...
Yuzhen Shen, Qian Shen, Manni Chen, Rufang Liu   +3 more
wiley   +1 more source

The role of histidine 265 in antagonist binding to the neurokinin-1 receptor.

Journal of Biological Chemistry, 1994
Previous studies suggested that the antagonist binding site in the neurokinin-1 receptor is composed of phylogenetically conserved residues, while phylogenetically divergent residues affect the conformation of the binding site. To test this hypothesis, we investigated the role of conserved residues in antagonist binding.
T M, Fong, H, Yu, M A, Cascieri, D, Underwood, C J, Swain, C D, Strader   +5 more
openaire   +2 more sources

Chronic Prurigo of Nodular Type: A Review

Acta Dermato-Venereologica, 2017
Prurigo nodularis (PN) is a subtype of chronic prurigo presenting single to multiple symmetrically distributed, hyperkeratotic and intensively itching papules and nodules.
Claudia Zeidler, Athanasios Tsianakas, Manuel Pereira, Hartmut Ständer, Gil Yosipovitch, Sonja Ständer   +5 more
doaj   +1 more source

Medicinal and Crop Protection Chemistry: Breaking Barriers, Building Synergies

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
A unified view of medicinal and crop protection chemistry reveals shared scientific progress, common challenges, and new opportunities for cross‐disciplinary collaboration. Bridging expertise across both fields could accelerate innovation and actively encourage more sustainable solutions.
Giulia Cazzaniga, Giusy L. Fratello, Alexander T. Apostle, Roberto Orru, David M. Barber, Silvia Gazzola   +5 more
wiley   +1 more source