Results 91 to 100 of about 160,899 (200)

IUPHAR review: Navigating the role of preclinical models in pain research

Pharmacological Research
Chronic pain is a complex and challenging medical condition that affects millions of people worldwide. Understanding the underlying mechanisms of chronic pain is a key goal of preclinical pain research so that more effective treatment strategies can be ...
Seyed Asaad Karimi, Fatama Tuz Zahra, Loren J. Martin   +2 more
doaj   +1 more source

Dronabinol for chemotherapy-induced nausea and vomiting unresponsive to antiemetics

Cancer Management and Research, 2016
Megan Brafford May,1 Ashley E Glode2 1Department of Pharmacy, Baptist Health Lexington, Lexington, KY, USA; 2Department of Clinical Pharmacy, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus ...
May MB, Glode AE
doaj  

Spotlight on the perioperative use of maropitant citrate

Veterinary Medicine: Research and Reports, 2017
Bonnie L Hay Kraus Department of Veterinary Clinical Sciences, Iowa State University College of Veterinary Medicine, Ames, IA, USA Abstract: Neurokinin-1 (NK-1) receptors are present in both the central nervous system and peripheral tissues. Substance P (
Hay Kraus BL
doaj  

Safety assessment of neurokinin-1 receptor antagonist: real-world adverse event analysis from the FAERS database

Frontiers in Pharmacology
BackgroundAprepitant, fosaprepitant, and netupitant are three common neurokinin-1 receptor antagonists (NK-1RAs) used to prevent chemotherapy-induced nausea and vomiting, following highly or moderately emetogenic chemotherapy.
Chuanli Yang, Chuanli Yang, Chuanli Yang, Pengyang Xu, Teng Wu, Yunhe Fan, Qingqing Li, Jijun Zhang, Xiaobing Shen, Xiaobing Shen, Xiushan Dong   +10 more
doaj   +1 more source

[Neurokinin-1 receptor antagonists for postoperative nausea and vomiting: a systematic review and meta-analysis]. [PDF]

Braz J Anesthesiol, 2020
Murakami C, Kakuta N, Satomi S, Nakamura R, Miyoshi H, Morio A, Saeki N, Kato T, Ohshita N, Tanaka K, Tsutsumi YM.   +10 more
europepmc   +1 more source

Prevention of acute chemotherapy-induced nausea and vomiting: the role of palonosetron

Cancer Management and Research, 2009
Emilio Bajetta, Sara Pusceddu, Valentina Guadalupi, Monika Ducceschi, Luigi CelioMedical Oncology Unit 2, Fondazione IRCCS “Istituto Nazionale dei Tumori”, Milan, ItalyAbstract: Prevention of nausea and vomiting is the main goal of ...
Emilio Bajetta, Sara Pusceddu, Valentina Guadalupi, et al   +3 more
doaj  

Revisiting substance P in migraine: a methodological approach inspired by anti-CGRP and anti-PACAP success

The Journal of Headache and Pain
Substance P, previously dismissed as a therapeutic target for migraine due to the failure of neurokinin-1 receptor antagonists, warrants renewed attention.
Lanfranco Pellesi, Lars Edvinsson
doaj   +1 more source

Efficacy of neurokinin-1 receptor antagonists in the prevention of chemotherapy-induced nausea and vomiting in patients receiving carboplatin-based chemotherapy: A systematic review and meta-analysis.

Critical reviews in oncology/hematology, 2018
M. Di Maio, C. Baratelli, P. Bironzo, F. Vignani, E. Bria, E. Sperti, M. Marcato, F. Roila   +7 more
semanticscholar   +1 more source

Neurokinin-1 receptor antagonists in preventing acute and delayed nausea and vomiting in patients receiving highly emetogenic chemotherapy

Zhongguo linchuang yanjiu
Objective To investigate the efficacy of different neurokinin- 1（NK-1）receptor antagonists（aprepitant,fosaprepitant,netupitant）in preventing acute and delayed nausea and vomiting in patients receiving highly emetogenic chemotherapy（HEC）,and to compare ...
FENG Alei,ZHOU Fengge,YANG Zhe
doaj   +1 more source

Effect of Neurokinin-1 Receptor Antagonists on Experimental Postoperative Adhesion: A Systematic Review and Meta-Analysis with Trial Sequential Analysis of Preclinical Studies. [PDF]

Medicina (Kaunas)
Hwang HJ, Choi GJ, Choi YS, Kim BG, Kang H.   +4 more
europepmc   +1 more source