Results 81 to 90 of about 160,899 (200)

Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations

Drug Design, Development and Therapy, 2017
Bernardo Leon Rapoport,1 Matti Aapro,2 Martin R Chasen,3 Karin Jordan,4 Rudolph M Navari,5 Ian Schnadig,6 Lee Schwartzberg7 1The Medical Oncology Centre of Rosebank, Johannesburg, South Africa; 2Breast Center, Genolier Cancer Center, Genolier ...
Rapoport BL, Aapro M, Chasen MR, Jordan K, Navari RM, Schnadig I, Schwartzberg L   +6 more
doaj  

Neurokinin-1 Receptor Antagonists as a Potential Novel Therapeutic Option for Osteosarcoma Patients. [PDF]

J Clin Med, 2023
Robinson P, Rosso M, Muñoz M.
europepmc   +1 more source

Research progress in therapeutic drugs for chemotherapy-induced nausea and vomiting

Zhongguo linchuang yanjiu
"Chemotherapy-induced nausea and vomiting（CINV）is a common adverse reaction in tumor treatment,which seriously affects patients􀆳 quality of life and treatment compliance.
WANG Jin,HAN Jiapeng,LI Ying,WANG Jirong
doaj   +1 more source

Aprepitant and Fosaprepitant for Preventing Nausea and Vomiting in Patients Receiving Highly Emetogenic Chemotherapy—A Real-World Study

Current Oncology
Chemotherapy-induced nausea and vomiting substantially impair patients’ quality of life despite considerable advances in supportive care. Neurokinin-1 receptor antagonists, including oral aprepitant and intravenous fosaprepitant, constitute essential ...
Beyza Ünlü, Hacer Demir, Sena Ece Davarcı, Yaşar Culha, Duygu Özaşkın, Fariz Emrah Özkan, Sedat Yıldız, Canan Yıldız, Meltem Baykara   +8 more
doaj   +1 more source

New tachykinin peptides and nociception

Japanese Dental Science Review, 2013
Hemokinin-1 (HK-1) and endokinins are peptides predicted from a new mammalian tachykinin gene, TAC4. The amino acid sequences derived from rat/mouse HK-1 and human HK-1 are not identical; however, the effects induced by intracerebroventricular or ...
Toshikazu Nishimori, Rumi Naono-Nakayama, Tetsuya Ikeda   +2 more
doaj   +1 more source

Computational Analysis of the Neurokinin-1 Receptor Interactions with Antagonists [PDF]

Biophysical Journal, 2021
Marcelo Cardoso dos, Reis Melo, Cesar de, la Fuente-Nunez   +3 more
openaire   +1 more source

Treatment-resistant prurigo nodularis: challenges and solutions

Clinical, Cosmetic and Investigational Dermatology, 2019
Eric H Kowalski,1 Diana Kneiber,1 Manuel Valdebran,2 Umangi Patel,1 Kyle T Amber1 1Department of Dermatology, University of Illinois at Chicago, Chicago, IL, USA; 2Department of Dermatology, University of California, Irvine, Irvine, CA, USA Abstract ...
Kowalski EH, Kneiber D, Valdebran M, Patel U, Amber KT   +4 more
doaj  

Challenges in the Development of Intravenous Neurokinin-1 Receptor Antagonists: Results of a Safety and Pharmacokinetics Dose-Finding, Phase 1 Study of Intravenous Fosnetupitant. [PDF]

Clin Pharmacol Drug Dev, 2022
Tyler T, Schultz A, Venturini A, Giuliano C, Bernareggi A, Spezia R, Voisin D, Stella V.   +7 more
europepmc   +1 more source

Profile of netupitant/palonosetron (NEPA) fixed dose combination and its potential in the treatment of chemotherapy-induced nausea and vomiting (CINV)

Drug Design, Development and Therapy, 2014
Rudolph M Navari Cancer Care Program, Eastern Europe, World Health Organization, Mishawaka, IN, USA; Indiana University School of Medicine, South Bend, IN, USA; South Bend Medical Services Corporation, IN, USA Abstract: Chemotherapy-induced ...
Navari RM
doaj  

Skin codelivery of contact sensitizers and neurokinin-1 receptor antagonists integrated in microneedle arrays suppresses allergic contact dermatitis. [PDF]

J Allergy Clin Immunol, 2022
Bandyopadhyay M, Morelli AE, Balmert SC, Ward NL, Erdos G, Sumpter TL, Korkmaz E, Kaplan DH, Oberbarnscheidt MH, Tkacheva O, Shufesky WJ, Falo LD, Larregina AT.   +12 more
europepmc   +1 more source