Results 161 to 170 of about 15,518,026 (208)

The effects of neurokinin A, neurokinin B, and eledoisin on substance P analysis

Journal of Clinical Monitoring, 1991
Commercial sources for neuropeptide radioimmunoassays have made this sensitive tool available to clinical investigators for monitoring the potential involvement of neuropeptides in pain modulation. We measured substance P-like immunoreactivity in the plasma, saliva, and pericardial fluid of subjects with and without pain (chronic and acute) to ...
R J, Naukam, W C, Parris, J R, Kambam, J B, Kruskal   +3 more
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The Rat Isolated Portal Vein: A Preparation Sensitive to Neurokinins, Particularly Neurokinin B

European Journal of Pharmacology, 1987
The rat isolated portal vein is a pharmacological preparation more sensitive to neurokinin B than to any other neurokinin or tachykinin. The preparation is more sensitive to C-terminal partial sequences of substance P (SP) particularly SP-(6-11) than to the whole undecapeptide.
Paolo Rovero, R Mathison, S Dion
exaly   +3 more sources

Placental and umbilical cord levels of neurokinin B and neurokinin B receptor in pre‐eclampsia

International Journal of Gynecology & Obstetrics, 2009
Neurokinin B (NKB) is traditionally classified as a neurotransmitter that is found in discrete neurons and immune cells [1]. Recently, it was found that the placenta—a tissue devoid of nerves—expresses the gene encoding NKB [2]. Page et al. [2] proposed that excessive secretion of NKB by the placenta could induce pre-eclampsia. We assessed the level of
Yanyan, Liu, Xi, Chen, Hanping, Chen
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Neurokinin A and B

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1991
The chemical features, pharmacological and biochemical characteristics of novel mammalian tachykinin peptides, neurokinin A and neurokinin B are described and are compared with those of substance P, a representative of tachykinin family.
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Mapping of neurokinin b in the cat brainstem

Anatomy and Embryology, 2005
We studied the distribution of neurokinin B-immunoreactive cell bodies and fibers in the cat brainstem using an indirect immunoperoxidase technique. The highest density of immunoreactive fibers was found in the motor trigeminal nucleus, the laminar and alaminar spinal trigeminal nuclei, the facial nucleus, the marginal nucleus of the brachium ...
I, Cuadrado, R, Coveñas, L A, Aguilar, J A, Aguirre, J, Rioja, J A, Narvaez   +5 more
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Specific agonists for neurokinin B receptors

European Journal of Pharmacology, 1987
A series of analogues of the partial sequence NKB-(4-10) (H-Asp-Phe-Phe-Val-Gly-Leu-Met.NH2) was prepared in an attempt to identify selective agonists for the neurokinin B receptor type. The compounds were tested in the dog carotid artery, the rabbit pulmonary artery and the rat portal vein to evaluate their affinity for the receptors of substance P ...
G, Drapeau, P, d'Orléans-Juste, S, Dion, N E, Rhaleb, D, Regoli   +4 more
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The role of neurokinin B in pre-eclampsia

Hospital Medicine, 2001
Pre-eclampsia, a life-threatening disease unique to pregnancy, has been called a disease of theories. To date, there has been no widely accepted predictive test or therapeutic intervention to prevent or delay pre-eclampsia. The discovery of a new placental hormone, neurokinin B, may finally help to answer some of the past mysteries.
N M, Page, P J, Lowry
openaire   +2 more sources

Stimulation of Cl Secretion by Neurokinin A and Neurokinin B in Canine Tracheal Epithelium

American Review of Respiratory Disease, 1988
Abstract We studied the effects of neurokinin A (NKA) and neurokinin B (NKB), the mammalian-derived tachykinins, on the electrical and ion transport properties of canine tracheal epithelium. Both tachykinins dose-dependently increased short-circuit current (Isc) when added to the mucosal (NKA: = 24.2 ± 2.4 µA/cm2, KD = 9 nM; NKB: = 14.
J, Tamaoki, I F, Ueki, J H, Widdicombe, J A, Nadel   +3 more
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[The structure-function organization of neurokinin A and neurokinin B molecules. II. Theoretical conformational analysis of neurokinin B].

Biofizika, 2005
The spatial structure of a neurokinin B molecule was investigated by the method of theoretical conformational analysis. The conformational analysis of this molecule indicated that the possible structure of neurokinin B under polar conditions may be described by five families of low-energy conformations possessing a conformationally relatively rigid C ...
G A, Agaeva, N N, Kerimli, N M, Godzhaev
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Distribution of neurokinin A-like and neurokinin B-like immunoreactivity in human peripheral tissues

Regulatory Peptides, 1991
Using specific radioimmunoassay and immunocytochemistry for neurokinin A (NKA) and neurokinin B (NKB), distribution and localization of the two peptides in human peripheral tissues were studied. Both NKA-like immunoreactivity (NKA-LI) and NKB-like immunoreactivity (NKB-LI) were present in the walls of the gut and gall bladder and in the pancreas.
S, Kishimoto, K, Tateishi, H, Kobayashi, K, Kobuke, T, Hagio, Y, Matsuoka, G, Kajiyama, A, Miyoshi   +7 more
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