Results 41 to 50 of about 1,065,066 (238)

Calcineurin Is Universally Involved in Vesicle Endocytosis at Neuronal and Nonneuronal Secretory Cells

Cell Reports, 2014
Calcium influx triggers and accelerates endocytosis in nerve terminals and nonneuronal secretory cells. Whether calcium/calmodulin-activated calcineurin, which dephosphorylates endocytic proteins, mediates this process is highly controversial for ...
Xin-Sheng Wu, Zhen Zhang, Wei-Dong Zhao, Dongsheng Wang, Fujun Luo, Ling-Gang Wu   +5 more
doaj   +1 more source

Shared and unique effects of ApoEε4 and pathogenic gene mutation on cognition and imaging in preclinical familial Alzheimer’s disease

Alzheimer’s Research & Therapy, 2023
Background Neuropsychology and imaging changes have been reported in the preclinical stage of familial Alzheimer’s disease (FAD). This study investigated the effects of APOEε4 and known pathogenic gene mutation on different cognitive domains and circuit ...
Meina Quan, Qi Wang, Wei Qin, Wei Wang, Fangyu Li, Tan Zhao, Tingting Li, Qiongqiong Qiu, Shuman Cao, Shiyuan Wang, Yan Wang, Hongmei Jin, Aihong Zhou, Jiliang Fang, Longfei Jia, Jianping Jia   +15 more
doaj   +1 more source

Lipid Metabolic Alterations in the ALS–FTD Spectrum of Disorders

Biomedicines, 2022
There is an increasing interest in the study of the relation between alterations in systemic lipid metabolism and neurodegenerative disorders, in particular in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD).
Juan Miguel Godoy-Corchuelo, Luis C. Fernández-Beltrán, Zeinab Ali, María J. Gil-Moreno, Juan I. López-Carbonero, Antonio Guerrero-Sola, Angélica Larrad-Sainz, Jorge Matias-Guiu, Jordi A. Matias-Guiu, Thomas J. Cunningham, Silvia Corrochano   +10 more
doaj   +1 more source

How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome [PDF]

, 2014
Thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic uraemic syndrome (aHUS) are acute, rare life-threatening thrombotic microangiopathies that require rapid diagnosis and treatment.
Goodship, T, Scully, M
core   +1 more source

Microglia/macrophages require vitamin D signaling to restrain neuroinflammation and brain injury in a murine ischemic stroke model

Journal of Neuroinflammation, 2023
Vitamin D deficiency is associated with worse clinical outcomes after ischemic stroke; nevertheless, the pathophysiological mechanisms remain largely unexplored.
Pan Cui, Wanting Lu, Junjie Wang, Fei Wang, Xiyue Zhang, Xiaodan Hou, Fang Xu, Yan Liang, Guoliang Chai, Junwei Hao   +9 more
doaj   +1 more source

Crying and feeding problems in infancy and cognitive outcome in preschool children born at risk : a prospective population study [PDF]

, 2009
Objective: To investigate whether regulatory problems, i.e., crying and feeding problems in infants > 3 months of age, predict cognitive outcome in preschool children born at risk even when controlled for confounding factors.
Alvarez, Anderson, Andrea Schreier, Anuntaseree, Arbuckle, Armstrong, Aylward, Bacharach, Bartram, Bauer, Baumeister, Becker, Becker, Beery, Beery, Bergman, Boekaerts, Bornstein, Brandt, Brandt, Braus, Breslau, Browne, Burgemeister, Burgemeister, Byrne, Böhm, Carvajal, Casaer, Casaer, Castellanos, Chatoor, Childers, Cohen, Dahl, DeGangi, DeGangi, Dieter Wolke, Dubowitz, Dunn, Egger, El-Faddagh, Frings, Gabriele Schmid, Gale, Golding, Gomez-Benito, Gray, Griffiths, Hair, Hanson, Hedegaard, Hiscock, Johnson, Khashan, Kiese, Kiese-Himmel, Klein, Klenberg, Kline, Laucht, Laucht, Laucht, Lepkin, Lindberg, Lindberg, Lindstam, Liu, Lou, Luiz, Lundqvist, Lundqvist-Persson, Marlow, McCall, McDermott, Minde, Mortensen, Nordberg, Northstone, Overman, Papousek, Papousek, Papousek, Peterson, Porges, Posner, Rao, Rees, Reijneveld, Reilly, Remschmidt, Renate Meyer, Richman, Riegel, Ryckman, Schermelleh-Engel, Scott, Skovgaard, St James-Roberts, St James-Roberts, St James-Roberts, St James-Roberts, Tabachnik, Thunström, Tirosh, Tong, Turkheimer, van der Wal, von Hofacker, von Hofacker, von Kries, Wake, Weinstock, West, Wolke, Wolke, Wolke, Wolke, Wolke, Wolke, Wolke, Wolke, Wolke, Wright, Wurmser, Wurmser, Wurmser   +126 more
core   +1 more source

Feline vestibular disorders. Part II: diagnostic approach and differential diagnosis. [PDF]

, 1999
Results of a neurological examination usually permit localisation of a vestibular disorder to either the central or peripheral parts of the vestibular system. Many different disorders located in the same part of the vestibular system will produce similar
LeCouteur, RA, Vernau, KM
core  

Health Effects Associated With Electronic Cigarette Use: Automated Mining of Online Forums. [PDF]

, 2020
BACKGROUND:Our previous infodemiological study was performed by manually mining health-effect data associated with electronic cigarettes (ECs) from online forums.
Hristidis, Vagelis, Hua, My, Sadah, Shouq, Talbot, Prue   +3 more
core  

Guided self-help interventions for mental health disorders in children with neurological conditions: study protocol for a pilot randomised controlled [PDF]

, 2016
Background: Rates of mental health disorders are significantly greater in children with physical illnesses than in physically well children. Children with neurological conditions, such as epilepsy, are known to have particularly high rates of mental ...
Bennett, S, Coughtrey, A, DeJong, M, Heyman, I, Shafran, R, Simmonds, J, Stephenson, T, Varadkar, S   +7 more
core   +2 more sources

Schizophrenia Spectrum Disorders: Linking Motor and Process Skills, Sensory Patterns, and Psychiatric Symptoms [PDF]

, 2020
Background: Consistent evidence suggests sensory abnormalities and skill deficits in people with Schizophrenia Spectrum Disorder (SSD). Further exploration of their sensory patterns and performance skills is warranted to promote community participation ...
Falk-Kessler, Janet, Halperin, Lola
core   +3 more sources