Results 71 to 80 of about 8,760 (227)

A Brainstem Radiomics Framework to Distinguish Progressive Supranuclear Palsy from Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Differentiating progressive supranuclear palsy (PSP) from Parkinson's disease (PD) can be clinically challenging. In the neuroimaging field, radiomics has emerged as a promising approach to capture subtle microstructural and textural image alterations, improving differential diagnoses.
Chiara Camastra, Jolanda Buonocore, Antonio Augimeri, Camilla Calomino, Maria Giovanna Bianco, Alessia Sarica, Pier Paolo Arcuri, Aldo Quattrone, Andrea Quattrone   +8 more
wiley   +1 more source

Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease [PDF]

, 2013
Recent studies suggest a variety of factors characterize substantia nigra neurons vulnerable to Parkinson's disease, including the transcription factors pituitary homeobox 3 (Pitx3) and orthodenticle homeobox 2 (Otx2) and the trophic factor receptor ...
Andersson, Bergman, Bradford, Bäckman, Charles Watson, Chu, Chu, Chung, Chung, Cotrufo, Darios, Deniz Kirik, Di Salvio, Di Salvio, Dickson, Double, Fearnley, Franklin, Fuchs, Gad, Garcia-Reitbock, George Paxinos, Gibb, Glenda M. Halliday, Greene, Halliday, Helen M. Cooper, Hwang, Kay L. Double, Kim, Kim, Korotkova, Lachlan H. Thompson, Lai Wing Sun, Le, Lebel, Lesnick, Lin, Manitt, Matsuda, Mcritchie, Nagahara, Nunes, Orme, Osborne, Paxinos, Prensa, Rangasamy, Reyes, Saucedo-Cardenas, Shatzmiller, Simeone, Simon, Simon, Smidt, Smidt, Smidt, Stefanie Reyes, Sullivan, Tcherkezian, Thomas, Van Den Munckhof, Veronica Cottam, Xu, Yang, Yuhong Fu, Zhao   +66 more
core   +1 more source

Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer, Oswaldo Lorenzo‐Betancor, Dong‐Hui Chen, Kimmy Su, Marika Bogdani, Anna J. Park, Minsuh Kim, Joshua Weiss, Malia Callier, Ella H. Chiu, Sarah Fish, Jennifer L. Witt, Wendy H. Raskind, Marie Y. Davis, C. Dirk Keene, Cyrus P. Zabetian   +15 more
wiley   +1 more source

Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression. [PDF]

, 2011
Several studies have proposed that brain glutamate signaling abnormalities and glial pathology have a role in the etiology of major depressive disorder (MDD).
Akil, H, Barchas, JD, Bernard, R, Bunney, WE, Jones, EG, Kerman, IA, Myers, RM, Schatzberg, AF, Thompson, RC, Watson, SJ   +9 more
core  

Ceruloplasmin and iron in Alzheimer's disease and Parkinson's disease: a synopsis of recent studies. [PDF]

, 2012
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field.Ceruloplasmin (Cp) concentration and oxidative activity in serum are lowered in Parkinson's disease (PD).
Jóhannesson, Torkell, Kristinsson, Jakob, Snaedal, Jón, Tórsdóttir, Gudlaug   +3 more
core   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Recent trends and developments in pyrolysis-gas chromatography: review [PDF]

, 2008
Pyrolysis-gas chromatography (Py-GC) has become well established as a simple, quick and reliable analytical technique for a range of applications including the analysis of polymeric materials.
Arias, Armitage, Aslan, Asperger, Asperger, Asperger, Asperger, Bertini, Beyer, Blackledge, Blokker, Bonaduce, Bruck, Buckley, Buco, Campbell, Casas-Catalán, Causin, Challinor, Challinor, Challinor, Chang, Chiavari, Choi, Choi, Colombini, De Koeijer, De la Cruz-Canizares, Dignac, Doménech-Carbó, Doménech-Carbó, Dunn, Dzierzega-Lecznar, Dzierzega-Lecznar, Egan, Erickson, Evans, Evans, Fabbri, Fabbri, Fanter, Fifield, Flodin, Garcette-Lepecq, Gleixner, González-Vila, Goodacre, Greenwood, Greenwood, Greenwood, Greenwood, Guo, Gupta, Göbbels, Gözet, Halket, Halket, Heffenden, Herrera, Horrocks, Ikeya, Ishikawa, Islas, Jakab, Jamin, Jansson, Jarde, Jia, Jin, Jose Gonzalez-Rodriguez, Karina L. Sobeih, Kechang, Kochanowski, Kumooka, Lattimer, Lazaro, Learner, Levy, Li, Ling, Liu, Mao, Marinari, Marinari, Mark Baron, Marques, Maynard, Meruva, Metz, Moldoveanu, Mowry, Munson, Mäkinen, Nierop, Odermatt, Odermatt, Oguz, Ohshima, Osete-Cortina, Osete-Cortina, Osete-Cortina, Park, Parsi, Parsi, Parsi, Parsi, Partouche, Pasch, Peacock, Pel, Pel, Perng, Perng, Petsch, Poerschmann, Poirier, Prasad, Prati, Raghavan, Raulin, Ristau, Ristolainen, Rodriguez, Ross, Räisänen, Sakayanagi, Scalarone, Schmidt, Schwarzinger, Sephton, Sessions, Snyder, Stauffer, Stout, Stout, Stout, Suelves, Sugden, Sun, Sundarrajan, Suuronen, Takayasu, Takayasu, Tanczos, Thomsen, Tsai, Tsuge, Tsuge, Tzamtzis, Urakami, Uyar, Uyar, Vanderborgh, Volkman, Wampler, Wampler, Wampler, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, White, Wilkes, Wilkes, Yamamoto, Yang, Yaylayan, Yinon, Zhang, Zhou, Zhu, Zimmerman, Zlotnick, Çoban-Yildiz, Łakomy   +179 more
core   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Development of a Competition-Binding Assay to Determine Binding Affinity of Molecules to Neuromelanin via Fluorescence Spectroscopy

Biomolecules, 2019
Neuromelanin, the polymeric form of dopamine which accumulates in aging neuronal tissue, is increasingly recognized as a functional and critical component of a healthy and active adult human brain.
Jackson Fink, Heather Pathak, John Smith, Cindy Achat-Mendes, Robert L. Haining   +4 more
doaj   +1 more source

The whole-brain pattern of magnetic susceptibility perturbations in Parkinson's disease [PDF]

, 2016
Although iron-mediated oxidative stress has been proposed as a potential pathomechanism in Parkinson's disease, the global distribution of iron accumulation in Parkinson's disease has not yet been elucidated.
Acosta-Cabronero, J, Betts, MJ, Butryn, M, Cardenas-Blanco, A, Galazky, I, Nestor, PJ, Valdes-Herrera, JP   +6 more
core   +1 more source