Results 31 to 40 of about 5,990 (215)

Studies on fazadinium bromide (AH 8165): A new non-depolarizing neuromuscular blocking agent [PDF]

open access: yesCanadian Anaesthetists’ Society Journal, 1976
Intravenous dose-response relationships were used to correlate neuromuscular paralysis with the effects of fazadinium (AH 8165) on autonomic mechanisms in anaesthetized cats and rhesus monkeys and with cardiovascular effects in man. In cats and monkeys neuromuscular paralysis of the twitch responses of the gastrocnemius muscle by fazadinium was ...
R, Hughes, J P, Payne, N, Sugai
openaire   +2 more sources

Neuronal effects of Sugammadex in combination with Rocuronium or Vecuronium. [PDF]

open access: yes, 2017
Rocuronium (ROC) and Vecuronium (VEC) are the most currently used steroidal non-depolarizing neuromuscular blocking (MNB) agents. Sugammadex (SUG) rapidly reverses steroidal NMB agents after anaesthesia.
Aldasoro Celaya, Martín   +10 more
core   +1 more source

Preparing for the unexpected: special considerations and complications after sugammadex administration

open access: yesBMC Anesthesiology, 2017
Sugammadex, a modified gamma-cyclodextrin, has changed clinical practice of neuromuscular reversal dramatically. With the introduction of this selective relaxant binding agent, rapid and reliable neuromuscular reversal from any depth of block became ...
Hajime Iwasaki   +3 more
doaj   +1 more source

Conventional reversal of rocuronium-induced neuromuscular blockade by sugammadex in Korean children: pharmacokinetics, efficacy, and safety analyses

open access: yesFrontiers in Pharmacology, 2023
Background: Sugammadex is known to reverse neuromuscular blockade induced by non-depolarizing agents. In children, the recommended dose for reversal of moderate neuromuscular blockade is 2 mg/kg.
Sang-Hwan Ji   +17 more
doaj   +1 more source

A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]

open access: yes, 2012
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J   +2 more
core   +2 more sources

Anesthesia in the surgery of strabismus: role of anesthetic agents in the ocular deviation and surgical outcome [PDF]

open access: yes, 2015
Purpose: To determine whether the changes in the ocular alignment following general anesthesia, maintained with two different inhalational anesthetic agents, sevoflurane and desflurane, can be used as a predictor for surgical outcomes in children with ...
Arrico, Loredana   +5 more
core   +1 more source

Malignant hyperthermia – state of knowledge

open access: yesJournal of Education, Health and Sport, 2022
Malignant hyperthermia (MH) is a relatively rare, but potentially lethal genetic disorder. That disease is characterized by hypermetabolic response of the skeletal muscles caused by exposure to triggering agents e.g. volatile anesthetics or depolarizing
Michał Perszke   +6 more
doaj   +1 more source

A systematic review and meta-analysis of the use of succinylcholine to facilitate tracheal intubation in neonates

open access: yesAin Shams Journal of Anesthesiology, 2021
Use of succinylcholine in neonates is surrounded by many controversies. The need to review this topic stems from the fact that though there is an abundance of information, but there are divergent views regarding its use in neonates.
Bhavna Gupta, Priyanka Mishra
doaj   +1 more source

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

open access: yes, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A.   +5 more
core   +1 more source

Extreme Paralysis Following Rocuronium Administration in a Myasthenia Gravis Patient: A Case Report

open access: yesClinical Practice and Cases in Emergency Medicine, 2023
Introduction: The use of paralytics during rapid sequence intubation (RSI) in patients with myasthenia gravis (MG) remains a controversial topic in emergency medicine.
Kelsey Billups   +2 more
doaj   +1 more source

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