Results 251 to 260 of about 191,422 (338)

Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation

open access: yesAdvanced Science, EarlyView.
This study presents a novel porous drug‐loading coating for cochlear electrodes, utilizing MA‐PDMS infused with GelMA hydrogel containing dexamethasone and MXene nanoparticles. The coating enhances biocompatibility, enables sustained drug release, reduces fibrosis, and preserves residual hearing post‐CI.
Lei Ren   +15 more
wiley   +1 more source

Accurate Delivery of Mesenchymal Stem Cell Spheroids With Platelet‐Rich Fibrin Shield: Enhancing Survival and Repair Functions of Sp‐MSCs in Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
Autologous plasma‐derived platelet‐rich fibrin (PRF) is prepared as a protective shield for mesenchymal stem cell spheroids (Sp‐MSCs). PRF forms a fibrin shield to protect Sp‐MSCs from the oxidative stress environment. The nutrients in PRF, particularly the α‐granules, can enhance the repair function of Sp‐MSCs.
Jinglve Zhang   +10 more
wiley   +1 more source

CHARACTERIZING MULTIPLE STATES OF NEURONAL DEVELOPMENT IN THE ADULT HIPPOCAMPUS USING SINGLE-NUCLEI RNA-SEQ

open access: yesIBRO Neuroscience Reports, 2023
Natali Rasetto   +10 more
doaj  

Neuronal plasticity: a new paradigm for resilience

open access: diamond, 2008
Pierre J. Magistretti   +1 more
openalex   +1 more source

Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing reveals cellular heterogeneity in adrenal incidentalomas, identifying distinct tumor cell populations. Clusterin is recognized as a biomarker for adrenocortical tumors, correlating with established markers. MYCN‐positive clusters in pheochromocytomas indicated poorer survival.
Meng Wang   +18 more
wiley   +1 more source

Editorial: Regulatory Peptides in Neuroscience and Endocrinology: A New Era Begins

open access: yesFrontiers in Endocrinology, 2019
Limei Zhang   +3 more
doaj   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

open access: yesAdvanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He   +11 more
wiley   +1 more source

3D‐Printed Biomimetic Vascular Scaffold Crosslinked with Heparan Sulfate for Sustained Release of PDGFB‐LG4 Fusion Protein Promotes Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Fusion protein PDGFB‐LG4 exhibits superior osteoinductive and angiogenic activity compared to PDGFB. The PCLHS‐PDGFB‐LG4 scaffold, featuring perfusable and permeable vascular‐like networks, promotes angiogenesis and osteogenesis through the sustained release of PDGFB‐LG4, thereby accelerating the bone defect repair process.
Jiahua Duan   +6 more
wiley   +1 more source

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