Results 281 to 290 of about 999,561 (325)

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

Advanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi, Zejun Gao, Yang Qiu, Renfeng Wang, Keyong Tian, Bo Yue, Xinyu Zhang, Peng Zhang, Ziqi Wu, Qingwen Zhu, Zhenzhen Liu, Zhuoyao Ma, Xueying Zhou, Yu Han, Jun Chen, Jianhua Qiu, DingJun Zha   +16 more
wiley   +1 more source

[Neuronal plasticity changes in the central amygdala and prelimbic cortex network in mice with chronic unpredictable mild stress-induced depression]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Liu D, Chen Z, Wang Y, Li X, Zhao P, Zheng H.   +5 more
europepmc   +1 more source

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Neurotrophins and Neuronal Plasticity

Science, 1995
There is increasing evidence that neurotrophins (NTs) are involved in processes of neuronal plasticity besides their well-established actions in regulating the survival, differentiation, and maintenance of functions of specific populations of neurons.
H. Thoenen
semanticscholar   +4 more sources

Adenosine and neuronal plasticity

Life Sciences, 1996
Adenosine is considered an important neuromodulator of the nervous system acting at pre-, post- and non-synaptic levels. In the present review we describe how adenosine modifies paired-pulse facilitation (PPF), posttetanic depression (PTD), long-term potentiation (LTP), long-term depression (LTD) and depotentiation at the hippocampus, and therefore how
Alexandre de Mendonça, Joaquim A. Ribeiro   +1 more
openaire   +3 more sources

Plasticity of neuronal receptors

The FASEB Journal, 1989
This article describes ways in which receptors, key components of signal propagation through a synapse, can mediate changes in that propagation. Changes occur at four levels: in the signal-transducing capability of a single receptor molecule, in the number of receptors per cell, in the subcellular placement of receptor molecules, and in the ...
Jose Santiago Aguilar, A. F. Skorupa, J. Sullivan, William L. Klein   +3 more
openaire   +3 more sources

Brain Aging and Neuronal Plasticity^a

Annals of the New York Academy of Sciences, 1992
In the present paper three aspects of the aging processes and their physiopathological implications will be presented: neuronal death, the information handling capabilityof neurons, and the processes of interneuronal communication.
L. F. AGNATI, BENFENATI, FABIO, V. SOLFRINI, G. BIAGINI, K. FUXE, D. GUIDOLIN, C. CARANI, I. ZINI   +7 more
openaire   +5 more sources

Neuronal plasticity and memory.

American Journal of Orthopsychiatry, 1969
All of the somatic therapies useful in psychiatry modify synaptic membrane activity. Future investigations may discover means by which pathways can be selectively activated or deactivated, not only by learning but with the aid of chemical interventions.
openaire   +2 more sources

Establishment and plasticity of neuronal polarity

Journal of Neuroscience Research, 1999
A fundamental feature of neurons is that they possess a polarized morphology, typified by a single long axon and several short dendrites. This cellular polarity forms the basis for directionalized rapid signaling, and for bi-directional trophic signaling, in neuronal circuits. While a catalog of structural, molecular, and functional differences between
openaire   +3 more sources

Gangliosides and Neuronal Plasticity

1986
This volume contains the Proceedings of the Meeting "Neuronal plasticity and gangliosides" which was held at Mantova, Italy, on May 29-31, 1985, as a satellite to the Tenth Meeting of the International Society for Neurochemistry, (Riva del Garda, Italy, May 19-24,1985).
Konrad Sandhoff, Yoshitaka Nagai, Guido Tettamanti, Robert W. Ledeen, Gino Toffano   +4 more
openaire   +2 more sources