Results 31 to 40 of about 1,846,055 (403)
Diabetic neuropathy and neuropathic pain: a (con)fusion of pathogenic mechanisms?
Pain, 2020 Neuropathy is a common complication of long-term diabetes that impairs quality of life by producing pain, sensory loss and limb amputation. The presence of neuropathy in both insulin-deficient (type 1) and insulin resistant (type 2) diabetes along with ...
N. Calcutt
semanticscholar +1 more source
Pain, 2020 Neuropathic pain is a complex, heterogeneous disorder that affects approximately 8% of the total adult human population and comeswith significant burden for both the patient and health care system.
E. Joosten, Glenn Franken
semanticscholar +1 more source
Single-Blind Placebo-Controlled Response Test with Phenytoin 10% Cream in Neuropathic Pain Patients
Pharmaceuticals, 2018 Background: Phenytoin cream applied topically has been explored in neuropathic pain conditions. In several case series, phenytoin 5% and 10% cream could reduce pain in a clinically relevant way with a fast onset of action within 30 min, and with positive
David J. Kopsky +1 more
doaj +1 more source
Apoptotic gene expression in neuropathic pain [PDF]
, 2008 Pain initiated or caused by a primary lesion or dysfunction in the nervous system is defined as neuropathic pain. It results from direct injury to nerves in the peripheral or central nervous system and is associated with several clinical symptoms ...
Annalucia Migliozzi +6 more
core +2 more sources
Challenges of neuropathic pain: focus on diabetic neuropathy
Journal of neural transmission, 2020 Neuropathic pain is a frequent condition caused by a lesion or disease of the central or peripheral somatosensory nervous system. A frequent cause of peripheral neuropathic pain is diabetic neuropathy.
D. Rosenberger +4 more
semanticscholar +1 more source
Phenytoin Cream for the Treatment of Neuropathic Pain: Case Series
Pharmaceuticals, 2018 BACKGROUND: Neuropathic pain can be disabling, and is often difficult to treat. Within a year, over half of all patients stop taking their prescribed neuropathic pain medication, which is most probably due to side effects or disappointing analgesic ...
David J. Kopsky, Jan M. Keppel Hesselink
doaj +1 more source
Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]
, 2016 INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina +6 more
core +2 more sources
NEUROPATHIC PAIN AS A CHALLENGING CLINICAL ENTITY IN OLDER ADULTS
Anti-Aging Eastern Europe, 2022 Neuropathic pain is a challenging clinical entity in older adults. Certain clinical conditions such as diabetes mellitus, cerebrovascular diseases and infections may lead to neuropathic pain in the elderly.
Ilke Coskun Benlidayi
doaj +1 more source
Clinical Case Reports, 2019 Key Clinical Message Acute paraplegia after treatment with intrathecal methotrexate requires a complete spinal cord neuroimaging as well as electrodiagnostic examination.
Carmen Montejo +4 more
doaj +1 more source
Neuropathic pain treatment: still a challenge
Neurology International, 2016 Neuropathic pain (NP) is the result of a series of conditions caused by diseases or lesions to the somatosensory system. Due to the better understanding of NP pathophysiology previously unexplored therapies have been used with encouraging results.
Osvaldo J.M. Nascimento +10 more
doaj +1 more source