Results 31 to 40 of about 176,935 (377)
Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study. [PDF]
PLoS ONE, 2018 The underlying mechanisms of neuropathic pain remain to be elucidated. Basic animal research has suggested that lysophosphatidic acids, which are bioactive lipids produced by autotaxin from lysophosphatidylcholine, may play key roles in the initiation ...
Ken Kuwajima +10 more
doaj +1 more source
Mechanisms of Neuropathic Pain [PDF]
Neuron, 2006 Neuropathic pain refers to pain that originates from pathology of the nervous system. Diabetes, infection (herpes zoster), nerve compression, nerve trauma, "channelopathies," and autoimmune disease are examples of diseases that may cause neuropathic pain. The development of both animal models and newer pharmacological strategies has led to an explosion
Richard A. Meyer, James N. Campbell
openaire +3 more sources
Biomarker of extracellular matrix remodelling C1M and proinflammatory cytokine IL-6 are related to synovitis and pain in end-stage knee osteoarthritis patients [PDF]
Pain. 2017 Jul;158(7):1254-1263, 2019 Little is known about local and systemic biomarkers in relation to synovitis and pain in end-stage osteoarthritis (OA) patients. We investigated the associations between the novel extracellular matrix biomarker, C1M, and local and systemic interleukin 6 (IL-6) with synovitis and pain.
arxiv +1 more source
Oxcarbazepine for neuropathic pain [PDF]
Cochrane Database of Systematic Reviews, 2013 Neuropathic pain is difficult to treat. Oxcarbazepine is an anticonvulsant drug closely related to carbamazepine and is reportedly better tolerated. Oxcarbazepine has been reported to be efficacious in the treatment of neuropathic pain.To determine the benefits and harms of oxcarbazepine for different forms of neuropathic pain.We searched the Cochrane ...
Muke Zhou +5 more
openaire +3 more sources
Walking with Neuropathic Pain: Paradoxical Shift from Burden to Support?
Case Reports in Medicine, 2015 Baclofen 5% cream can be used for the treatment of neuropathic pain. We describe an unusual case of a neuropathic pain patient with spinal cord injury.
David J. Kopsky +2 more
doaj +1 more source
Neuropathic pain in low back-related leg pain patients: What is the evidence of prevalence, characteristics, and prognosis in primary care? A systematic review of the literature. [PDF]
, 2017 This systematic review synthesizes literature describing prevalence, characteristics and prognosis of low back-related leg pain (LBLP) patients with neuropathic pain in primary care and/or similar settings. Inclusion and exclusion criteria were developed
Dunn, KM +4 more
core +2 more sources
Neuropathic pain in leprosy [PDF]
Leprosy Review, 2004 Chronic neuropathic pain in treated leprosy has received scant attention. In this article the concept, clinical features and diagnosis of neuropathic pain are reviewed. The possible pathophysiological mechanisms, treatment challenges and research needs in this area are discussed.
Maija Haanpää +2 more
openaire +3 more sources
PAIN Reports, 2018 . Introduction:. Previous studies reported a high prevalence of neuropathic pain in leprosy, being especially present in “pharmacologically cured” patients.
Irina Raicher +9 more
doaj +1 more source
Neuropeptide Y and its involvement in chronic pain [PDF]
2017,Neuroscience, 2017 Chronic pain is a serious condition that significantly impairs the quality of life, affecting an estimate of 1.5 billion people worldwide. Despite the physiological, emotional and financial burden of chronic pain, there is still a lack of efficient treatments.
arxiv +1 more source
Case Reports in Medicine, 2012 Central neuropathic pain in patients with multiple sclerosis (MS) is a common debilitating symptom, which is mostly treated with tricyclic antidepressants or antiepileptics. Unfortunately, the use of these drugs is often limited due to adverse events. We
David J. Kopsky +2 more
doaj +1 more source