Results 31 to 40 of about 185,348 (295)
Case Reports in Medicine, 2012 Central neuropathic pain in patients with multiple sclerosis (MS) is a common debilitating symptom, which is mostly treated with tricyclic antidepressants or antiepileptics. Unfortunately, the use of these drugs is often limited due to adverse events. We
David J. Kopsky +2 more
doaj +1 more source
Oral ketamine vs placebo in patients with cancer-related neuropathic pain [PDF]
, 2018 Ketamine hydrochloride is used as an adjuvant treatment for cancer-related neuropathic pain, but evidence of its effectiveness is limited.1 Findings of a large trial investigating the use of ketamine for general cancer pain were negative, but the ...
Fallon, Marie T. +6 more
core +4 more sources
Neuropathic pain in leprosy [PDF]
Leprosy Review, 2004 Chronic neuropathic pain in treated leprosy has received scant attention. In this article the concept, clinical features and diagnosis of neuropathic pain are reviewed. The possible pathophysiological mechanisms, treatment challenges and research needs in this area are discussed.
Maija Haanpää +2 more
openaire +3 more sources
BMC Neurology, 2011 Background Neuropathic pain must be correctly diagnosed for optimal treatment. The questionnaire named Neuropathic Pain Symptom Inventory (NPSI) was developed in its original French version to evaluate the different symptoms of neuropathic pain.
Lungenhausen Margitta +5 more
doaj +1 more source
Diagnosis and management of trigeminal neuropathic pains [PDF]
, 2011 Trigeminal neuropathic pains have presented diagnostic and therapeutic challenges to providers. In addition, knowledge of pathophysiology, current classification systems, taxonomy and phenotyping of these conditions are incomplete.
Napeñas, JJ, Zakrzewska, JM
core +1 more source
Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study. [PDF]
PLoS ONE, 2018 The underlying mechanisms of neuropathic pain remain to be elucidated. Basic animal research has suggested that lysophosphatidic acids, which are bioactive lipids produced by autotaxin from lysophosphatidylcholine, may play key roles in the initiation ...
Ken Kuwajima +10 more
doaj +1 more source
Mas-related G-protein–coupled receptors inhibit pathological pain in mice [PDF]
, 2010 An important objective of pain research is to identify novel drug targets for the treatment of pathological persistent pain states, such as inflammatory and neuropathic pain.
Altier +49 more
core +2 more sources
Investigation of the Neuropathic Pain Caused by Syringomyelia Associated with Chiari I Malformation [PDF]
Asian Spine Journal, 2019 Study Design Retrospective cohort study. Purpose To investigate the correlation between the syrinx morphology and neuropathic pain caused by syringomyelia associated with Chiari I malformation.
Toshitaka Seki +5 more
doaj +1 more source
Current Opinion in Neurology, 2001 Damage to peripheral nerves triggers a cascade of events in axotomized sensory neurones that are generally believed to be responsible for the generation of neuropathic pain. Recent data in animal models show that alterations in the properties of undamaged neurones that project into a damaged nerve can also play an important role.
Alice Goodman
openalex +3 more sources
Use of the painDETECT tool in rheumatoid arthritis suggests neuropathic and sensitization components in pain reporting. [PDF]
, 2014 Rheumatoid arthritis (RA) is an inflammatory autoimmune condition typified by systemic inflammation targeted toward synovial joints. Inhibition of proinflammatory networks by disease-modifying antirheumatic drugs, eg, methotrexate and biologic therapies,
Ahmed, S +4 more
core +2 more sources