Results 61 to 70 of about 169,611 (201)
Use of anticonvulsants drugs for neuropathic painful conditions [PDF]
, 2008 Neuropathic pain, a form of chronic pain initiated and sustained by an insult to the peripheral or central nervous system, is a challenge to clinicians as it does not respond well to traditional pain therapies.
Afshan, Gauhar, Hussain, Aziza Mohammad
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TNF-α and neuropathic pain - a review [PDF]
, 2010 Tumor necrosis factor alpha (TNF-α) was discovered more than a century ago, and its known roles have extended from within the immune system to include a neuro-inflammatory domain in the nervous system.
Lawrence Leung, Catherine M Cahill
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Cells, 2020 Neuropathic pain exerts a global burden caused by the lesions in the somatosensory nerve system, including the central and peripheral nervous systems. The mechanisms of nerve injury-induced neuropathic pain involve multiple mechanisms, various signaling ...
Ti-Yen Yeh +5 more
doaj +1 more source
Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. [PDF]
, 2020 Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (DRG).
Basbaum, Allan I +8 more
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Frontiers in Cellular Neuroscience, 2019 Neuropathic pain (NP) is among the most intractable comorbidities of spinal cord injury. Dysregulation of non-coding RNAs has also been implicated in the development of neuropathic pain. Here, we identified a novel lncRNA, PKIA-AS1, by using lncRNA array
Jian-Zhong Hu +18 more
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Neuropathic pain: targeting the melatonin MT2 receptor
South African Family Practice, 2016 Neuropathic pain affects a large proportion of the population and reduces a person’s ability to perform optimally. In South Africa, there are a host of factors that hinder the correct diagnosis and treatment of neuropathic pain.
N. Smith, H. Ismail, N. Schellack
doaj +1 more source
Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]
, 2018 BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila +6 more
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Treadmill running on neuropathic pain: via modulation of neuroinflammation
Frontiers in Molecular NeuroscienceNeuropathic pain is a type of chronic pain caused by an injury or somatosensory nervous system disease. Drugs and exercise could effectively relieve neuropathic pain, but no treatment can completely stop neuropathic pain. The integration of exercise into
Wei-Chun He +7 more
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Statins and Neuropathic Pain: A Narrative Review
Pain and Therapy, 2020 The frequently prescribed drug class of statins have pleiotropic effects and have been implicated in neuropathic pain syndromes. This narrative review examines studies of statin-induced neuropathic pain which to date have been conducted only in animal ...
Joseph V. Pergolizzi +5 more
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Comparison of Efficiencies of Neurological Physical Examination, Neurothesiometer and PainDETECT Questionnaire in Diagnosing Diabetic Neuropathy [PDF]
, 2020 Objective: To compare the efficacies of neurological physical examination, neurothesiometer and PainDETECT questionnaire in diagnosing diabetic neuropathy.
Aftab, M. F. (Muhammad) +5 more
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