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Background Most women with anovulatory infertility show polycystic ovarian syndrome (PCOS), and androgen excess is known as a key factor involved in pathogenicity of PCOS.
Yoko Urata+7 more
doaj +1 more source
Neuropeptide Y and Asthma Clinical Course [PDF]
Background: The spectrum of clinical manifestations and pathogenetic mechanisms of bronchial asthma (BA) is very wide. Given the complex pathogenesis and syndromic nature of BA, it is not surprising that there is no single universal biomarker.
Yanina S. Shkatova+5 more
doaj +1 more source
The effect of human wharton’s jelly-derived mesenchymal stem cells on MC4R, NPY, and LEPR gene expression levels in rats with streptozotocin-induced diabetes [PDF]
Objective(s): Type 1 diabetes (T1D) is an autoimmune disease resulting from inflammatory destruction of islets β-cells. Nowadays, progress in cell therapy, especially mesenchymal stem cells (MSCs) proposes numerous potential remedies for T1D. We aimed to
Fatemeh Sabet Sarvestani+5 more
doaj +1 more source
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica+6 more
wiley +1 more source
Roles of Neuropeptide Y in Neurodegenerative and Neuroimmune Diseases
Neuropeptide Y (NPY) is a neurotransmitter or neuromodulator that mainly exists in the nervous system. It plays a neuroprotective role in organisms and widely participates in the regulation of various physiological processes in vivo.
Chunrong Li+5 more
semanticscholar +1 more source
Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor
Neuropeptide Y (NPY) receptors belong to the G-protein-coupled receptor superfamily and have important roles in food intake, anxiety and cancer biology1,2.
Zhen-lin Yang+25 more
semanticscholar +1 more source
The Role of Neuropeptide Y in Cardiovascular Health and Disease
Neuropeptide Y (NPY) is an abundant sympathetic co-transmitter, widely found in the central and peripheral nervous systems and with diverse roles in multiple physiological processes.
Cheryl M. J. Tan+5 more
semanticscholar +1 more source
Pharmacogenetic markers of antipsychotic-induced weight gain: leptin and neuroepeptide Y
Antipsychotic drugs are a critical modality in managing of schizophrenia. Although medications can be highly effective, response varies and some patients derive considerably less benefit than others.
V. S. Dobrodeeva+3 more
doaj +1 more source
Correlations of Neuropeptide Y and Adiponectin Serum Levels in Obese Type 2 Diabetics in Relation to Insulin Resistance [PDF]
Background The importance of obesity in the progression of Type 2 Diabetes Mellitus (T2DM) is represented by defective biochemical markers' production and release that may interact with each other, resulting in negative outcomes for the diabetic state ...
Nada Hasan, Shatha Ali
doaj +1 more source
Lower Plasma Neuropeptide Y Level in Patients With Atypical Febrile Convulsions
Febrile convulsion (FC) is the most common neurological disease in children. Cases with seizures that persist for more than 15 minutes or recurrent seizures within the same febrile illness are considered to be atypical and may have a different prognosis.
Lung-Chang Lin+3 more
doaj +1 more source