Results 31 to 40 of about 21,250,288 (213)
Perspectives and potential approaches for targeting neuropilin 1 in SARS-CoV-2 infection
Molecular Medicine, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel type b coronavirus responsible for the COVID-19 pandemic. With over 224 million confirmed infections with this virus and more than 4.6 million people dead because of it, it is ...
Svetlana P. Chapoval, Achsah D. Keegan
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Journal of Oral Biology and Craniofacial Research, 2021 Background: Soluble Neuropilin-1 (sNRP-1) is a glycoprotein with angiogenic and immune regulatory functions, which correspond to processes deeply involved with periodontal diseases.
Diego Prieto +5 more
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Amelioration of neuropilin-1 and RAGE/matrix metalloproteinase-2 pathway-induced renal injury in diabetic rats by rosuvastatin [PDF]
Archives of Biological Sciences, 2021 Advanced glycation end-products (AGEs) induce the production of reactive oxygen species (ROS) and extra cellular matrix (ECM) degradation via suppression of neuropilin-1 (NRP-1) and interaction with AGE-receptors (RAGE).
Nabi Rabia +7 more
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MiR-200c sensitizes Olaparib-resistant ovarian cancer cells by targeting Neuropilin 1
Journal of Experimental & Clinical Cancer Research, 2020 Background Ovarian cancer (OC) is the most lethal gynecological malignancy and the second leading cause of cancer-related death in women. Treatment with PARP inhibitors (PARPi), such as Olaparib, has been recently introduced for OC patients, but ...
Enrica Vescarelli +15 more
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Neuropilin-1 biases dendrite polarization in the retina [PDF]
Development, 2013 The majority of neurons in the nervous system exhibit a polarized morphology, with multiple short dendrites and a single long axon. It is clear that multiple factors govern polarization in developing neurons, and the biased accumulation of intrinsic determinants to one side of the cell, coupled with responses to asymmetrically localized extrinsic ...
Elizabeth M, Kita +4 more
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Neuropilin-1 Regulates the Secondary CD8 T Cell Response to Virus Infection
mSphere, 2019 Neuropilin-1 (Nrp1) plays important roles in axonal guidance in neurons and in the growth of new blood vessels. There is also a growing appreciation for roles played by neuropilin-1 in the immune response.
Ji Young Hwang +3 more
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Epidermal expression of neuropilin 1 protects murine keratinocytes from UVB-induced apoptosis. [PDF]
PLoS ONE, 2012 BACKGROUND: Neuropilin 1 (NRP1) is expressed on several cell types including neurons and endothelial cells, where it functions as an important regulator in development and during angiogenesis.
Anna Riese +7 more
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Expression and regulation of neuropilin-1 in human astrocytomas [PDF]
International Journal of Cancer, 2000 Vascular endothelial growth factor (VEGF), through activation of its endothelial receptors VEGFR-1 and VEGFR-2, is an important positive modulator of tumor angiogenesis and edema in solid tumors such as malignant astrocytomas. Neuropilin-1 (Npn-1) is a transmembrane receptor expressed by both endothelial and non-endothelial cells, including tumor cells.
H, Ding +6 more
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Nature Communications, 2019 O-glycosylation of neuropilin-1 is involved in cancer migration and invasion. Here, the authors show that defects in N-glycosylation of two neuropilin-1 splice variants enhance the co-internalisation of Met, it’s interaction with β1-integrin, and ...
Xiuping Huang +10 more
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Neuropilin‐1 is not a marker of human Foxp3+ Treg [PDF]
European Journal of Immunology, 2009 AbstractTreg are immune cells that play a critical role in the regulation of the immune response. Although the transcription factor Foxp3 is widely accepted as the standard marker of Treg, specific surface markers are needed to better characterize these cells and decipher their mechanisms of action.
Milpied, Pierre +9 more
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