Results 11 to 20 of about 114,586 (238)
Quinones as Neuroprotective Agents. [PDF]
Antioxidants (Basel), 2023 Quinones can in principle be viewed as a double-edged sword in the treatment of neurodegenerative diseases, since they are often cytoprotective but can also be cytotoxic due to covalent and redox modification of biomolecules. Nevertheless, low doses of moderately electrophilic quinones are generally cytoprotective, mainly due to their ability to ...
Cores Á +4 more
europepmc +5 more sources
Fiscalin Derivatives as Potential Neuroprotective Agents. [PDF]
Pharmaceutics, 2022 Neurodegenerative diseases (ND) share common molecular/cellular mechanisms that contribute to their progression and pathogenesis. In this sense, we are here proposing new neuroprotection strategies by using marine-derived compounds as fiscalins.
Barreiro S +6 more
europepmc +4 more sources
Carboxyfullerenes as neuroprotective agents [PDF]
Proceedings of the National Academy of Sciences, 1997 Two regioisomers with C 3 or D 3 symmetry of water-soluble carboxylic acid C 60 derivatives, containing three malonic acid groups per molecule, were synthesized and found to be equipotent free radical scavengers in solution as assessed by EPR ...
Dugan, Laura L. +9 more
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Carbon nanotubes as neuroprotective agents. [PDF]
Explor Neuroprotective TherCarbon nanotubes, an emerging class of carbon nanomaterials, possess tremendous potential for application in biotechnology and biomedicine particularly in neurological disorders. Carbon nanotubes owing to their fascinating properties have the potential to revolutionize medicine and technology, particularly in the realm of drug delivery, biosensing ...
Wilson DL, Ahlawat J, Narayan M.
europepmc +3 more sources
A Review of Neuroprotective Agents [PDF]
Current Medicinal Chemistry, 2004 The brain remains an area where little corrective surgery can be performed and the reversal of damage is almost impossible. Recently, reports of agents offering neuroprotection have begun to appear in the literature. The concept of neuroprotection is the administration of some agent, which should reverse some of the damage or prevent further damage ...
Margaret A. Brimble, Mark S. Levi
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Neuroprotective Agents in the Intensive Care Unit: -Neuroprotective Agents in ICU. [PDF]
J Pharmacopuncture, 2018 Neuroprotection or prevention of neuronal loss is a complicated molecular process that is mediated by various cellular pathways. Use of different pharmacological agents as neuroprotectants has been reported especially in the last decades. These neuroprotective agents act through inhibition of inflammatory processes and apoptosis, attenuation of ...
Panahi Y +5 more
europepmc +5 more sources
Neuroprotective agents in the management of glaucoma [PDF]
Eye, 2018 Glaucoma is an optic neuropathy, specifically a neurodegenerative disease characterized by loss of retinal ganglion cells (RGCs) and their axons. The pathogenesis of RGC loss in glaucoma remains incompletely understood and a broad range of possible mechanisms have been implicated.
Nucci C. +5 more
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Erythropoietin: a multimodal neuroprotective agent [PDF]
Experimental & Translational Stroke Medicine, 2009 The tissue protective functions of the hematopoietic growth factor erythropoietin (EPO) are independent of its action on erythropoiesis. EPO and its receptors (EPOR) are expressed in multiple brain cells during brain development and upregulated in the adult brain after injury.
Anna-Leena Sirén, Nadiya Byts
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Ginsenosides: A Potential Neuroprotective Agent [PDF]
BioMed Research International, 2018 Ginseng is a traditional Chinese medicine with a wide range of pharmacological activities. Ginsenosides are the major constituents of ginseng. Ginsenosides have the unique biological activity and medicinal value, such as antitumor, anti-inflammatory, antioxidation, and inhibition of cell apoptosis.
Mengmeng Zheng +9 more
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Current neuroprotective agents in stroke [PDF]
Turk J Phys Med RehabilWhat is expected from neuroprotection is to inhibit neuronal death and halt or decelerate the neuronal loss to lower the mortality rates, decrease disability, and improve the quality of life following an acute ischemic stroke. Several agents were described as neuroprotective up to date; however, there is still debate which to use in the ...
Yanık T, Yanık B.
europepmc +3 more sources