Antidotal and protective effects of mangosteen (Garcinia mangostana) against natural and chemical toxicities: A review [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Chemical and natural toxic compounds can harm human health through a variety of mechanisms. Nowadays, herbal therapy is widely accepted as a safe method of treating toxicity.
Aidin Mohammadi Zonouz +2 more
doaj +1 more source
Pharmacological Blockade of the Calcium Plateau Provides Neuroprotection Following Organophosphate Paraoxon Induced Status Epilepticus in Rats [PDF]
, 2016 Organophosphate (OP) compounds which include nerve agents and pesticides are considered chemical threat agents. Currently approved antidotes are crucial in limiting OP mediated acute mortality.
Ajdacic-Gross +43 more
core +2 more sources
Modulation of neurotrophic signaling pathways by polyphenols [PDF]
, 2015 Polyphenols are an important class of phytochemicals, and several lines of evidence have demonstrated their beneficial effects in the context of a number of pathologies including neurodegenerative disorders such as Alzheimer's and Parkinson's disease. In
Firuzi, Omidreza +3 more
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Neuroprotective Properties of Chitosan and Its Derivatives
Marine Drugs, 2010 Neuronal cells are extremely vulnerable and have a limited capacity for self-repair in response to injury. For those reasons, there is obvious interest in limiting neuronal damage.
Se-Kwon Kim, Ratih Pangestuti
doaj +1 more source
Results of the MRI substudy of the intravenous magnesium efficacy in stroke trial [PDF]
, 2009 <p><b>Background and Purpose:</b>Although magnesium is neuroprotective in animal stroke models, no clinical benefit was confirmed in the Intravenous Magnesium Efficacy in Stroke (IMAGES) trial of acute stroke patients.
Alger, J.R. +9 more
core +1 more source
Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat [PDF]
, 2004 Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and ...
Candelario-Jalil, Eduardo +4 more
core +1 more source
Nutraceutical Antioxidants as Novel Neuroprotective Agents
Molecules, 2010 A variety of antioxidant compounds derived from natural products (nutraceuticals) have demonstrated neuroprotective activity in either in vitro or in vivo models of neuronal cell death or neurodegeneration, respectively.
Daniel A. Linseman +2 more
doaj +1 more source
Neuroprotection in a Novel Mouse Model of Multiple Sclerosis [PDF]
, 2013 The authors acknowledge the support of the Barts and the London Charity, the Multiple Sclerosis Society of Great Britain and Northern Ireland, the National Multiple Sclerosis Society, USA, notably the National Centre for the Replacement, Refinement ...
A Compston +49 more
core +4 more sources
The Promise of Neuroprotective Agents in Parkinson’s Disease
Frontiers in Neurology, 2011 Parkinson’s Disease is characterized by loss of dopamine neurons in the substantia nigra of the brain. Since there are limited treatment options for PD, neuroprotective agents are currently being tested as a means to slow disease progression.
Judith ePotashkin, Stacey E Seidl
doaj +1 more source
Frontiers in Aging Neuroscience, 2023 BackgroundRecent studies on renin-angiotensin system (RAS) inhibitors have reported a reduced risk of Alzheimer’s disease (AD). Nevertheless, the effect of RAS inhibitor type and blood–brain barrier (BBB) permeability on the risk of AD is still unknown ...
Hyun Woo Lee +7 more
doaj +1 more source