Results 21 to 30 of about 114,586 (238)
Molecular Hydrogen as a Neuroprotective Agent [PDF]
Current Neuropharmacology, 2017 Oxidative stress and neuroinflammation cause many neurological disorders. Recently, it has been reported that molecular hydrogen (H2) functions as an antioxidant and anti-inflammatory agent. The routes of H2 administration in animal model and human clinical studies are roughly classified into three types, inhalation of H2 gas, drinking H2-dissolved ...
Masumi Iketani, Ikuroh Ohsawa
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Neuroprotective Agents in Glaucoma [PDF]
, 2011 1.1 Glaucoma as a neurodegenerative disorder Glaucoma is a multifactorial disease in which multiple genetic, systemic and environmental factors interact to precipitate the disease. Increased intraocular pressure (IOP) is believed to be one of the major factors responsible for glaucomatous cell death. (Guo et al., 2005).
George Kitsos, Eleni Bagli
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The Promise of Neuroprotective Agents in Parkinson?s Disease [PDF]
Frontiers in Neurology, 2011 Parkinson's disease (PD) is characterized by loss of dopamine neurons in the substantia nigra of the brain. Since there are limited treatment options for PD, neuroprotective agents are currently being tested as a means to slow disease progression. Agents targeting oxidative stress, mitochondrial dysfunction, and inflammation are prime candidates for ...
Judith A. Potashkin, Stacey E. Seidl
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A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). [PDF]
, 2014 Neurocognitive deficits are a major source of morbidity in survivors of cardiac arrest. Treatment options that could be implemented either during cardiopulmonary resuscitation or after return of spontaneous circulation to improve these neurological ...
Applegate, Patricia M +5 more
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Ginseng polysaccharides: A potential neuroprotective agent
Journal of Ginseng Research, 2021 The treatments of nervous system diseases (NSDs) have long been difficult issues for researchers because of their complexity of pathogenesis. With the advent of aging society, searching for effective treatments of NSDs has become a hot topic. Ginseng polysaccharides (GP), as the main biologically active substance in ginseng, has various biological ...
Chunchao Han +6 more
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Using 'dead or dependent' as an outcome measure in clinical trials in Parkinson's disease [PDF]
, 2014 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewedPublisher ...
Counsell, Carl +4 more
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Anti-Inflammatory activity of a polyphenolic extract from Arabidopsis thaliana in in vitro and in vivo models of Alzheimer's Disease [PDF]
, 2019 Alzheimer's disease (AD) is the most common neurodegenerative disorder and the primary form of dementia in the elderly. One of the main features of AD is the increase in amyloid-beta (Aβ) peptide production and aggregation, leading to oxidative stress ...
Casale, Assunta Maria +10 more
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Volatile anesthetics as a neuroprotective agent [PDF]
Korean Journal of Anesthesiology, 2011 Pharmacologic protection of brain from ischemic insult has been intensively investigated since the early 1960s [1] and a considerable amount of work has been performed to show the effectiveness of various drugs. Among these studies, anesthetic agents, including intravenous and volatile drugs, were shown to be promising agents.
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NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy [PDF]
, 2013 Alzheimer’s disease (AD) is a devastating neurodegenerative disease causing irreversible cognitive decline in the elderly. There is no disease-modifying therapy for this condition and the mechanisms underpinning neuronal dysfunction and neurodegeneration
Cowan, C.M., Mudher, A., Quraishe, S.
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Nutraceutical Antioxidants as Novel Neuroprotective Agents [PDF]
Molecules, 2010 A variety of antioxidant compounds derived from natural products (nutraceuticals) have demonstrated neuroprotective activity in either in vitro or in vivo models of neuronal cell death or neurodegeneration, respectively. These natural antioxidants fall into several distinct groups based on their chemical structures: (1) flavonoid polyphenols like ...
Natalie A. Kelsey +2 more
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