Results 91 to 100 of about 216,217 (284)

Estado Confusional Agudo após Corticoterapia Inalada [PDF]

, 2017
Background: The connection between corticotherapy and neuropsychiatric symptoms is widely known, being one of the first questions we need to assess when presenting with first episode psychiatric symptoms or confusional state.
Monteiro, J, Mota, D, Ribeiro, L, Santos, M, Venâncio, A   +4 more
core  

Demographic variables, clinical aspects, and medicolegal implications in a population of patients with adjustment disorder [PDF]

, 2016
INTRODUCTION: Although adjustment disorder (AD) is considered as residual diagnosis and receives little attention in research, it plays an important role in clinical practice and also assumes an increasingly important role in the field of legal medicine,
Anastasia, Annalisa, Bersani, Giuseppe, Colletti, Chiara, Cuoco, Valentina, Quartini, Adele, Rinaldi, Raffaella, Urso, Stefania   +6 more
core   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Psychiatric Impact of Tuberous Sclerosis Complex and Utilization of Mental Health Treatment [PDF]

, 2018
Tuberous sclerosis complex (TSC) is a multi-system, neurocutaneous disorder with neuropsychiatric features known as TSC-associated neuropsychiatric disorders (TAND).
Mowrey, Kate
core   +1 more source

Respiratory‐Limbic Coupling via a Thalamic Circuit Alleviates Anxiety

Advanced Science, EarlyView.
This study delineates a conserved preBötCGlu→PVT→CeA circuit that gates anxiety and respiration. Activation of this circuit is anxiolytic and respiratory‐stabilizing, while its inhibition has the opposite effect. Mechanistically, PVT exerts its anxiolytic action via a disinhibitory microcircuit: its inputs preferentially target CeL GABAergic neurons ...
Shangyu Bi, Xiaoyi Wang, Huichun Luo, Ziteng Yue, Tianjiao Deng, Yuhang Liu, Xinxin Chen, Jianxu Zhao, Luo Shi, Ning Ma, Lingyan Mao, Jing Ding, Jiwen Xu, Ti‐Fei Yuan, Sheng Wang, Fang Yuan   +15 more
wiley   +1 more source

Systematic review of psychological approaches to the management of neuropsychiatric symptoms of dementia [PDF]

, 2005
Objective: The authors systematically reviewed the literature on psychological approaches to treating the neuropsychiatric symptoms of dementia.Method: Reports of studies that examined effects of any therapy derived from a psychological approach that ...
Johnston, K, Katona, C, Livingston, G, Lyketsos, CG, Old Age Task Force World Fed, Paton, J   +5 more
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Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders [PDF]

, 2016
Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing data from animal model, epidemiological, and genomic studies that commonly used antihypertensive drugs may have a role in the pathogenesis or course of mood ...
Boal, Angela H., Dominiczak, Anna F., Mccallum, Linsay, Muir, Scott, Padmanabhan, Sandosh, Smith, Daniel J., Touyz, Rhian M.   +6 more
core   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Neuropsychiatric Symptoms in Parkinson’s Disease: Beyond Complications [PDF]

Frontiers in Psychiatry, 2016
Parkinson’s disease (PD) extends beyond movement to often encompass a range of psychiatric phenomena, such that it has been viewed as the prototypical neuropsychiatric disorder (1). While the movement disorder is primarily linked to a central dopamine deficit, neurodegenerative events in the main noradrenergic, serotoninergic, and cholinergic nuclei ...
openaire   +5 more sources

Modified Mediterranean Diet for Enrichment of Short Chain Fatty Acids: Potential Adjunctive Therapeutic to Target Immune and Metabolic Dysfunction in Schizophrenia? [PDF]

, 2017
Growing interest in gut and digestive processes and their potential link to brain and peripheral based inflammation or biobehavioral phenotypes has led to an increasing number of basic and translational scientific reports focused on the role of gut ...
Cadenhead, Kristen S, Depp, Colin, Joseph, Jamie, Schmid-Schönbein, Geert, Shih, Pei-An B   +4 more
core   +1 more source