Results 51 to 60 of about 4,618 (197)

MECHANISMS OF DISEASE Acute Oxygen-Sensing Mechanisms [PDF]

open access: yes, 2005
JOSEPH PRIESTLEY, ONE OF THE THREE SCIENTISTS CREDITED WITH THE discovery of oxygen, described the death of mice that were deprived of oxygen. However, he was also well aware of the toxicity of too much oxygen, stating, “For as a candle burns much faster
Buckler, Keith J.   +3 more
core  

Rapid Nongenomic Effects of Oestradiol on Gonadotrophin‐Releasing Hormone Neurones [PDF]

open access: yes, 2012
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/89550/1/j.1365-2826.2011.02135.x ...
Abe   +45 more
core   +1 more source

The moulting arthropod: a complete genetic toolkit review

open access: yesBiological Reviews, Volume 99, Issue 6, Page 2338-2375, December 2024.
ABSTRACT Exoskeletons are a defining character of all arthropods that provide physical support for their segmented bodies and appendages as well as protection from the environment and predation. This ubiquitous yet evolutionarily variable feature has been instrumental in facilitating the adoption of a variety of lifestyles and the exploitation of ...
Giulia Campli   +10 more
wiley   +1 more source

Dysfunctional Autophagy and Endolysosomal System in Neurodegenerative Diseases: Relevance and Therapeutic Options

open access: yesFrontiers in Cellular Neuroscience, 2020
Autophagy and endolysosomal trafficking are crucial in neuronal development, function and survival. These processes ensure efficient removal of misfolded aggregation-prone proteins and damaged organelles, such as dysfunctional mitochondria, thus allowing
Silvia Giovedì   +9 more
doaj   +1 more source

The T‐Type Calcium Channel CACNA1H is Required for Smooth Muscle Cytoskeletal Organization During Tracheal Tubulogenesis

open access: yesAdvanced Science, Volume 11, Issue 44, November 26, 2024.
Defects in the T‐type calcium channel CACNA1H cause defects in airway smooth muscle formation and its cytoskeletal organization in tracheal stenosis, and pharmacological increase of RhoA activity can partially attenuate these defects in mice. Analysis of human tracheal tissues suggests that a decrease in CACNA1H proteins is associated with tracheal ...
Ziying Liu   +15 more
wiley   +1 more source

mRNA decapping is an evolutionarily conserved modulator of neuroendocrine signaling that controls development and ageing

open access: yeseLife, 2020
Eukaryotic 5’−3’ mRNA decay plays important roles during development and in response to stress, regulating gene expression post-transcriptionally. In Caenorhabditis elegans, deficiency of DCAP-1/DCP1, the essential co-factor of the major cytoplasmic mRNA
Fivos Borbolis   +10 more
doaj   +1 more source

In vivo analysis of conserved C. elegans tomosyn domains. [PDF]

open access: yesPLoS ONE, 2011
Neurosecretion is critically dependent on the assembly of a macromolecular complex between the SNARE proteins syntaxin, SNAP-25 and synaptobrevin. Evidence indicates that the binding of tomosyn to syntaxin and SNAP-25 interferes with this assembly ...
Anna O Burdina   +4 more
doaj   +1 more source

Loss of the transcriptional repressor PAG-3/Gfi-1 results in enhanced neurosecretion that is dependent on the dense-core vesicle membrane protein IDA-1/IA-2. [PDF]

open access: yesPLoS Genetics, 2009
It is generally accepted that neuroendocrine cells regulate dense core vesicle (DCV) biogenesis and cargo packaging in response to secretory demands, although the molecular mechanisms of this process are poorly understood.
Tao Cai   +6 more
doaj   +1 more source

Neurosecretion Following Hypophysectomy

open access: yesExperimental Biology and Medicine, 1950
Elucidation of the various factors controlling the pituitary gland has been a major problem of science for many years. Harris(1) has admirably reviewed the literature concerning the neural control of the hypophysis. His statement. “The pars distalis of the pituitary may in general terms be described as a gland under nervous control but lacking a nerve ...
openaire   +3 more sources

Studies on the neurosecretion of thoracic ganglion in relation to reproduction of femaleMacrobrachium lanchesteri (de Man) [PDF]

open access: yes, 1981
The changes in the histology of thoracic ganglion in females ofMacro-brachium lanchesteri, prior to spawning and post parturial moult, have been described.
Katre Shakuntala, .   +2 more
core  

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