Results 131 to 140 of about 16,231 (234)

Insights into neurosteroids and their role in women with epilepsy

Frontiers in Global Women's Health
Epilepsy, is a serious neurological condition, characterized by recurring, unprovoked seizures and affects over 50 million people worldwide. Epilepsy has an equal prevalence in males and females, and occurs throughout the life span.
Lata Vadlamudi, Lata Vadlamudi, Daniel Paul Ashley, Daniel Paul Ashley, P. Emanuela Voinescu   +4 more
doaj   +1 more source

Epilepsy and Sex Hormones

Archives of Epilepsy, 2018
There is a mutual interaction between sex steroid hormones and epilepsy. Although female and male sex hormones and their metabolites access the brain via the blood brain barrier, they can also be synthesized de novo from cholesterol within the glia and ...
Emine GENÇ, Bülent Oğuz GENÇ
doaj   +1 more source

La expresión génica hipotalámica de la enzima Citocromo P450scc en ratas hembras es regulada positivamente por estrógeno y negativamente por progesterona [PDF]

, 2009
Los neuroesteroides son potentes moléculas modulatorias sintetizadas en sistema nervioso central y cuya actividad se restringe a dicho ámbito. En su síntesis participan enzimas del grupo del citocromo P450 (CP450) enzimas que no pertenecen a dicho grupo.
Cabrera, Ricardo, Giuliani, Fernando, Yunes, Roberto   +2 more
core  

O papel dos neurosteróides na depressão e ansiedade [PDF]

, 2016
Monografia realizada no âmbito da unidade de Estágio Curricular do Mestrado Integrado em Ciências Farmacêuticas, apresentada à Faculdade de Farmácia da Universidade de CoimbraEsteróides neuroativos que são sintetizados no cérebro e no sistema nervoso a ...
Mota, Joana Rita Marques
core  

Neurosteroids mediate and modulate the effects of pro-inflammatory stimulation and toll-like receptors on hippocampal plasticity and learning.

PLoS ONE
Pro-inflammatory changes contribute to multiple neuropsychiatric illnesses. Understanding how these changes are involved in illnesses and identifying strategies to alter inflammatory responses offer paths to potentially novel treatments.
Yukitoshi Izumi, Kazuko A O'Dell, Anil G Cashikar, Steven M Paul, Douglas F Covey, Steven J Mennerick, Charles F Zorumski   +6 more
doaj   +1 more source

Dissociating Allopregnanolone Mnemonic Effects from Sedation [PDF]

, 2012
Allopregnanolone (Allop) is a neurosteroid metabolite of progesterone. Allop modulates cognition, specifically learning and memory, but these effects are frequently confounded by its anxiolytic and sedative properties.
Hartman, Sarah B
core   +1 more source

Beyond boundaries: Neuroprotective effects of steroids and ecdysteroids in SH‐SY5Y cells ‐ A systematic review

Neuroprotection
Steroids and ecdysteroids have been shown to exhibit a range of biological effects, including anti‐inflammatory, anticancer, and neuroprotective. This systematic review aims to highlight the evidence‐based neuroprotective and antioxidant effects of ...
Bizhar Ahmed Tayeb, Isaac Kinyua Njangiru, Renáta Minorics   +2 more
doaj   +1 more source

Gender differences in the relationships among neurosteroid serum levels, cognitive function, and quality of life

Neuropsychiatric Disease and Treatment, 2018
Chien-Yu Chen,1 Chih-Ching Wu,2,3 Yu-Chi Huang,1 Chi-Fa Hung,1 Liang-Jen Wang4 1Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Molecular Medicine Research Center, Chang ...
Chen CY, Wu CC, Huang YC, Hung CF, Wang LJ   +4 more
doaj  

Mapping two neurosteroid-modulatory sites in the prototypic pentameric ligand-gated ion channel GLIC [PDF]

, 2018
Akk, Gustav, Bracamontes, John R., Budelier, Melissa M., Chen, Zi-Wei, Cheng, Wayland W. L., Covey, Douglas F., Evers, Alex S., Jiang, Xin, Krishnan, Kathiresan, Shin, Daniel J., Wang, Cunde   +10 more
core   +2 more sources

Neuroactive steroids for the treatment of depression and anxiety: gaps and promises. [PDF]

Eur Arch Psychiatry Clin Neurosci
Rupprecht R, Schüle C, Gudermann T.
europepmc   +1 more source