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Rapid effects of neurosteroids on neuronal plasticity and their physiological and pathological implications

Neuroscience Letters, 2021
Current neuroscience research on neurosteroids and their synthetic analogues - neuroactive steroids - clearly demonstrate their drug likeness in a variety of neurological and psychiatric conditions.
Eva Kudova
exaly   +2 more sources

Neurosteroids: non-genomic pathways in neuroplasticity and involvement in neurological diseases

Pharmacology & Therapeutics, 2018
Neurosteroids are neuroactive brain‐born steroids. They can act through non‐genomic and/or through genomic pathways. Genomic pathways are largely described for steroid hormones: the binding to nuclear receptors leads to transcription regulation ...
Laurence Lanfumey
exaly   +2 more sources

Neurosteroids: A potential target for neuropsychiatric disorders

Journal of Steroid Biochemistry and Molecular Biology
Su-Wan Hu, Siqi Yang
exaly   +2 more sources

Neuropeptidergic Control of Neurosteroids Biosynthesis.

Frontiers in neuroendocrinology (Print), 2022
Neurosteroids are steroids synthesized within the central nervous system either from cholesterol or by metabolic reactions of circulating steroid hormone precursors. It has been suggested that neurosteroids exert pleiotropic activities within the central
T. Ubuka, K. Tsutsui
semanticscholar   +1 more source

Sex Neurosteroids: hormones made by the brain for the brain.

Neuroscience Letters, 2021
In general, hippocampal neurons are capable of synthesizing sex steroids de novo from cholesterol, since the brain is equipped with all the enzymes required for the synthesis of estradiol and testosterone, the end products of sex steroidogenesis ...
L. Fester, G. Rune
semanticscholar   +1 more source

Neurosteroids: A novel promise for the treatment of stroke and post‐stroke complications

Journal of Neurochemistry, 2021
Stroke is the primary reason for death and disability worldwide, with few treatment strategies to date. Neurosteroids, which are natural molecules in the brain, have aroused great interest in the field of stroke.
Jia-Wei Xu   +10 more
semanticscholar   +1 more source

Neuroinflammation and psychiatric disorders: Relevance of C1q, translocator protein (18 kDa) (TSPO), and neurosteroids

World Journal of Biological Psychiatry, 2021
There is increasing evidence that neuroinflammatory processes may play a role in the pathophysiology of psychiatric disorders. Recently, the complement protein C1q and the translocator protein (18 kDa) (TSPO) have attracted considerable interest in this ...
R. Rupprecht   +3 more
semanticscholar   +1 more source

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