Results 1 to 10 of about 33,769 (117)

Research Progress on Intervention of Natural Products from Plants in Neurotoxicity of Acrylamide [PDF]

open access: yesShipin Kexue, 2023
Acrylamide (ACR) is a common toxic substance in foods, which can cause serious damage to human organs and systems, especially the nervous system. At present, there are no appropriate measures to prevent and treat ACR neurotoxicity.
ZHANG Mengyu, ZHANG Yanqing, FANG Leilei, XIE Junbo, WEI Yinghao
doaj   +1 more source

Kinin B2 Receptor Mediates Cisplatin-Induced Painful Peripheral Neuropathy by Intracellular Kinase Pathways and TRPA1 Channel Sensitisation

open access: yesPharmaceuticals, 2023
Chemotherapy-induced peripheral neuropathy is a severe clinical problem frequently associated with cisplatin use. Although its pathophysiology is poorly understood, it is known that kinin receptors and the transient receptor potential ankyrin 1 (TRPA1 ...
Gabriela Becker   +3 more
doaj   +1 more source

Neuroinflammation in Bilirubin Neurotoxicity

open access: yesJournal of Integrative Neuroscience, 2023
Bilirubin neurotoxicity is a serious consequence of hyperbilirubinemia, which is the most common disease of the neonatal period. Clinically, bilirubin neurotoxicity can result in motor deficit, auditory dysfunction, cerebral palsy, seizure and ...
Fanhui Zhang, Lihua Chen, Kewen Jiang
doaj   +1 more source

Assessing the association between cefepime percentage free trough level and neurotoxicity

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology, 2022
Background: Cefepime has a known association with neurotoxicity due to its ability to cross the blood–brain barrier. The symptoms of neurotoxicity are highly variable.
Aleena Zia   +3 more
doaj   +1 more source

Methotrexate-related central neurotoxicity: clinical characteristics, risk factors and genome-wide association study in children treated for acute lymphoblastic leukemia

open access: yesHaematologica, 2021
Symptomatic methotrexate-related central neurotoxicity (MTX neurotoxicity) is a severe toxicity experienced during acute lymphoblastic leukemia (ALL) therapy with potential long-term neurologic complications.
Marion K. Mateos   +18 more
doaj   +1 more source

Neurotoxicity by Cefepime: Case-Control Study [PDF]

open access: yesJournal of Neurocritical Care, 2014
Background: Cefepime is a fourth-generation cephalosporin widely used for empiric treatment of severe infections. Neurotoxicity by cefepime have been reported due to γ-aminobutyric acid A receptor inhibition or other mechanisms. The aim of this study was
Joong Koo Kang, Soon Bae Kim
doaj   +1 more source

Automated detection of immune effector cell‐associated neurotoxicity syndrome via quantitative EEG

open access: yesAnnals of Clinical and Translational Neurology, 2023
Objective To develop an automated, physiologic metric of immune effector cell‐associated neurotoxicity syndrome among patients undergoing chimeric antigen receptor‐T cell therapy.
Christine A. Eckhardt   +19 more
doaj   +1 more source

PAC1 Receptor Mediates Electroacupuncture-Induced Neuro and Immune Protection During Cisplatin Chemotherapy

open access: yesFrontiers in Immunology, 2021
Platinum-based chemotherapy is an effective treatment used in multiple tumor treatments, but produces severe side effects including neurotoxicity, anemia, and immunosuppression, which limits its anti-tumor efficacy and increases the risk of infections ...
Shanshan Li   +26 more
doaj   +1 more source

Auditory fatigue among call dispatchers working with headsets

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2018
Objectives To determine whether call center dispatchers wearing headsets are subject to auditory fatigue at the end of a work shift. Material and Methods Data was gathered at times when call centers were busiest. All call operators wore a headset for up
Thomas Venet   +8 more
doaj   +1 more source

Amoxicillin-Induced Neurotoxicity: Contribution of a Healthcare Data Warehouse to the Determination of a Toxic Concentration Threshold

open access: yesAntibiotics, 2023
Background: Amoxicillin (AMX)-induced neurotoxicity is well described and may be associated with AMX overexposure. No neurotoxic concentration threshold has been determined thus far.
Sébastien Lalanne   +7 more
doaj   +1 more source

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