Results 1 to 10 of about 345,747 (337)
The role of neuroimaging in neurotoxicity after chimeric antigen receptor T-cell therapy [PDF]
Therapeutic Advances in Neurological DisordersChimeric antigen receptor T-cell (CAR-T) therapy has become an established treatment for several haematological malignancies in relapse and is being evaluated for new indications.
Arian Lasocki +3 more
doaj +2 more sources
Biomarkers of cytokine release syndrome and neurotoxicity related to CAR-T cell therapy
Biomarker Research, 2018 Severe cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T cell (CAR-T) therapy can be life-threatening in some cases, and management of those toxicities is still a great challenge for physicians.
Zhenguang Wang, Weidong Han
doaj +2 more sources
Research Progress on Intervention of Natural Products from Plants in Neurotoxicity of Acrylamide [PDF]
Shipin Kexue, 2023 Acrylamide (ACR) is a common toxic substance in foods, which can cause serious damage to human organs and systems, especially the nervous system. At present, there are no appropriate measures to prevent and treat ACR neurotoxicity.
ZHANG Mengyu, ZHANG Yanqing, FANG Leilei, XIE Junbo, WEI Yinghao
doaj +1 more source
Pharmaceuticals, 2023 Chemotherapy-induced peripheral neuropathy is a severe clinical problem frequently associated with cisplatin use. Although its pathophysiology is poorly understood, it is known that kinin receptors and the transient receptor potential ankyrin 1 (TRPA1 ...
Gabriela Becker +3 more
doaj +1 more source
Neuroinflammation in Bilirubin Neurotoxicity
Journal of Integrative Neuroscience, 2023 Bilirubin neurotoxicity is a serious consequence of hyperbilirubinemia, which is the most common disease of the neonatal period. Clinically, bilirubin neurotoxicity can result in motor deficit, auditory dysfunction, cerebral palsy, seizure and ...
Fanhui Zhang, Lihua Chen, Kewen Jiang
doaj +1 more source
Cytokine release syndrome and associated neurotoxicity in cancer immunotherapy
Nature reviews. Immunology, 2021 A paradigm shift has recently occurred in the field of cancer therapeutics. Traditional anticancer agents, such as chemotherapy, radiotherapy and small-molecule drugs targeting specific signalling pathways, have been joined by cellular immunotherapies ...
E. Morris +3 more
semanticscholar +1 more source
Assessing the association between cefepime percentage free trough level and neurotoxicity
Antimicrobial Stewardship & Healthcare Epidemiology, 2022 Background: Cefepime has a known association with neurotoxicity due to its ability to cross the blood–brain barrier. The symptoms of neurotoxicity are highly variable.
Aleena Zia +3 more
doaj +1 more source
Mechanisms of Cadmium Neurotoxicity
International Journal of Molecular Sciences, 2023 Cadmium is a heavy metal that increasingly contaminates food and drink products. Once ingested, cadmium exerts toxic effects that pose a significant threat to human health.
Madelyn A. Arruebarrena +3 more
semanticscholar +1 more source
Postgraduate Medical Journal, 1979 Summary The peripheral and central neurotoxic effects of lithium carbonate are illustrated by 4 case histories. Lithium neurotoxicity is likely to be more common than the literature suggests. Neurological sequelae may be irreversible and may be associated with therapeutic serum levels. Prevention may be facilitated by more stringent case
P K, Newman, M, Saunders
openaire +2 more sources
Blood Cancer Journal, 2022 Chimeric antigen receptor (CAR) T-cell therapies are highly effective for multiple myeloma (MM) but their impressive efficacy is associated with treatment-related neurotoxicities in some patients.
A. Cohen +24 more
semanticscholar +1 more source