Results 21 to 30 of about 149,741 (293)

Automated detection of immune effector cell‐associated neurotoxicity syndrome via quantitative EEG

Annals of Clinical and Translational Neurology, 2023
Objective To develop an automated, physiologic metric of immune effector cell‐associated neurotoxicity syndrome among patients undergoing chimeric antigen receptor‐T cell therapy.
Christine A. Eckhardt, Haoqi Sun, Preeti Malik, Syed Quadri, Marcos Santana Firme, Daniel K. Jones, Meike vanSleuwen, Aayushee Jain, Ziwei Fan, Jin Jing, Wendong Ge, Husain H. Danish, Caron A. Jacobson, Daniel B. Rubin, Eyal Y. Kimchi, Sydney S. Cash, Matthew J. Frigault, Jong Woo Lee, Jorg Dietrich, M. Brandon Westover   +19 more
doaj   +1 more source

Antiretroviral neurotoxicity [PDF]

Journal of NeuroVirology, 2012
Combination antiretroviral therapy (CART) has proven to effectively suppress systemic HIV burden, however, poor penetration into the central nervous system (CNS) provides incomplete protection. Although the severity of HIV-associated neurocognitive disorders (HAND) has been reduced, neurological disease is expected to exert an increasing burden as HIV ...
Kevin, Robertson, Jeff, Liner, Rick B, Meeker   +2 more
openaire   +2 more sources

Auditory fatigue among call dispatchers working with headsets

International Journal of Occupational Medicine and Environmental Health, 2018
Objectives To determine whether call center dispatchers wearing headsets are subject to auditory fatigue at the end of a work shift. Material and Methods Data was gathered at times when call centers were busiest. All call operators wore a headset for up
Thomas Venet, Ayoub Bey, Pierre Campo, Joël Ducourneau, Quentin Mifsud, Charles Hoffmann, Aurélie Thomas, Marc Mouzé-Amady, Cécile Parietti-Winkler   +8 more
doaj   +1 more source

Amoxicillin-Induced Neurotoxicity: Contribution of a Healthcare Data Warehouse to the Determination of a Toxic Concentration Threshold

Antibiotics, 2023
Background: Amoxicillin (AMX)-induced neurotoxicity is well described and may be associated with AMX overexposure. No neurotoxic concentration threshold has been determined thus far.
Sébastien Lalanne, Guillaume Bouzillé, Camille Tron, Matthieu Revest, Elisabeth Polard, Eric Bellissant, Marie-Clémence Verdier, Florian Lemaitre   +7 more
doaj   +1 more source

Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats

Journal of Toxicology, 2018
Studies have revealed that anti-inflammatory agents could provide beneficial effect in lowering the incidence/progression of neurological diseases. Hence, this study sought to investigate the effect of essential oils from Nigeria ginger and turmeric ...
Ayodele Jacob Akinyemi, Philip Adeyemi Adeniyi   +1 more
doaj   +1 more source

PAC1 Receptor Mediates Electroacupuncture-Induced Neuro and Immune Protection During Cisplatin Chemotherapy

Frontiers in Immunology, 2021
Platinum-based chemotherapy is an effective treatment used in multiple tumor treatments, but produces severe side effects including neurotoxicity, anemia, and immunosuppression, which limits its anti-tumor efficacy and increases the risk of infections ...
Shanshan Li, Jin Huang, Yi Guo, Yi Guo, Yi Guo, Jiaqi Wang, Shanshan Lu, Bin Wang, Yinan Gong, Siru Qin, Suhong Zhao, Shenjun Wang, Shenjun Wang, Shenjun Wang, Yangyang Liu, Yangyang Liu, Yangyang Liu, Yuxin Fang, Yuxin Fang, Yuxin Fang, Yongming Guo, Yongming Guo, Yongming Guo, Zhifang Xu, Zhifang Xu, Zhifang Xu, Luis Ulloa   +26 more
doaj   +1 more source

A new approach on lithium-induced neurotoxicity using rat neuronal cortical culture: Involvement of oxidative stress and lysosomal/mitochondrial toxic Cross-Talk

Main Group Metal Chemistry, 2020
Lithium (Li) is a widely-used medication for the treatment of patients with bipolar disorder. Li causes different complications. One of the most important adverse effects of Li is neurotoxicity.
Yousefsani Bahareh Sadat, Askian Romina, Pourahmad Jalal   +2 more
doaj   +1 more source

Paresthesia in dentistry: The ignored neurotoxicity of local anesthetics

Heliyon, 2023
Local anesthetics are frequently used by dentists to relieve localized discomfort of the patient and improve treatment conditions. The risk of paresthesia after local anesthesia is frequently encountered in dental clinics.
Yong-zhen Tan, Rong-jia Shi, Bo-wen Ke, Ya-ling Tang, Xin-hua Liang   +4 more
doaj   +1 more source

Phase III randomized, placebo‐controlled, double‐blind study of monosialotetrahexosylganglioside for the prevention of oxaliplatin‐induced peripheral neurotoxicity in stage II/III colorectal cancer

Cancer Medicine, 2020
Background Monosialotetrahexosylganglioside (GM1) is a neuroprotective glycosphingolipid that repairs nerves. Oxaliplatin‐based chemotherapy is neurotoxic.
De‐shen Wang, Zhi‐qiang Wang, Gong Chen, Jie‐wen Peng, Wei Wang, Yan‐hong Deng, Feng‐hua Wang, Jian‐wei Zhang, Han‐lin Liang, Fen Feng, Chuan‐bo Xie, Chao Ren, Ying Jin, Si‐mei Shi, Wen‐hua Fan, Zhen‐hai Lu, Pei‐rong Ding, Feng Wang, Rui‐hua Xu, Yu‐hong Li   +19 more
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Change of intracellular calcium level causes acute neurotoxicity by antisense oligonucleotides via CSF route

Molecular Therapy: Nucleic Acids, 2023
Antisense oligonucleotides (ASOs) are promising therapeutics for intractable central nervous system (CNS) diseases. For this clinical application, neurotoxicity is one of the critical limitations.
Chunyan Jia, Su Su Lei Mon, Ying Yang, Maho Katsuyama, Kie Yoshida-Tanaka, Tetsuya Nagata, Kotaro Yoshioka, Takanori Yokota   +7 more
doaj   +1 more source