Results 11 to 20 of about 90,679 (311)
On Botulinum Neurotoxin Variability [PDF]
mBio, 2015 The rapidly growing number of botulinum neurotoxin sequences poses the problem of the possible evolutionary significance of the variability of these superpotent neurotoxins for toxin-producing Clostridium species. To progress in the understanding of this
C. Montecucco, M. Rasotto
semanticscholar +5 more sources
Tetanus and tetanus neurotoxin: From peripheral uptake to central nervous tissue targets
Journal of Neurochemistry, 2021 Tetanus is a deadly but preventable disease caused by a protein neurotoxin produced by Clostridium tetani. Spores of C. tetani may contaminate a necrotic wound and germinate into a vegetative bacterium that releases a toxin, termed tetanus neurotoxin ...
A. Megighian +4 more
semanticscholar +1 more source
Scientific Reports, 2021 Clostridium botulinum neurotoxin serotype A (BoNT/A) is a potent neurotoxin that serves as an effective therapeutic for several neuromuscular disorders via induction of temporary muscular paralysis.
Nicholas G. James +7 more
doaj +1 more source
Misincorporation Proteomics Technologies: A Review
Proteomes, 2021 Proteinopathies are diseases caused by factors that affect proteoform conformation. As such, a prevalent hypothesis is that the misincorporation of noncanonical amino acids into a proteoform results in detrimental structures.
Joel R. Steele +6 more
doaj +1 more source
Kinect-based objective evaluation of bradykinesia in patients with Parkinson's disease
Digital Health, 2023 Objective To quantify bradykinesia in Parkinson's disease (PD) with a Kinect depth camera-based motion analysis system and to compare PD and healthy control (HC) subjects. Methods Fifty PD patients and twenty-five HCs were recruited.
Zhuang Wu +15 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2022 BackgroundExercise plays an essential role in improving motor symptoms in Parkinson’s disease (PD), but the underlying mechanism in the central nervous system remains unclear.MethodsMotor ability was observed after 12-week treadmill exercise on a 1 ...
Weifang Tong +12 more
doaj +1 more source
Toxins, 2021 Intradermal injection of botulinum neurotoxin is a frequently performed procedure in aesthetic dermatology to improve facial skin tone, texture, fine wrinkles, and enlarged pores.
Nark-Kyoung Rho, Y. Gil
semanticscholar +1 more source
Journal of Neurology, Neurosurgery & Psychiatry, 2004 The genus Clostridium comprises a number of spore forming Gram positive, rod shaped bacilli. They are found in the intestines of numerous mammalian species including domestic animals, horses, chickens, and humans. They are also widely distributed in the soil and in marine and freshwater sediments.
Goonetilleke A, Harris JB
openaire +3 more sources
npj Parkinson's Disease, 2022 Postural abnormalities are common disabling motor complications affecting patients with Parkinson’s disease (PD). We proposed a summary index for postural abnormalities (IPA) based on Kinect depth camera and explored the clinical value of this indicator.
Ronghua Hong +13 more
doaj +1 more source
Frontiers in Plant Science, 2021 Grass pea is well-established as one of the most resilient and versatile crops that can thrive under extreme climatic circumstances such as cold, heat, drought, salt-affected soils, submergence, and excessive rainfall along with resistance to several ...
Arpita Das +4 more
doaj +1 more source