Results 21 to 30 of about 77,752 (388)

Botulinum Neurotoxins and Cancer—A Review of the Literature

Toxins, 2020
Botulinum neurotoxins (BoNT) possess an analgesic effect through several mechanisms including an inhibition of acetylcholine release from the neuromuscular junction as well as an inhibition of specific pain transmitters and mediators. Animal studies have
S. Mittal, B. Jabbari
semanticscholar   +1 more source

Application of botulinum toxin type A in gummy smile: case report

RGO: Revista Gaúcha de Odontologia, 2019
Gummy smile is one of the major complaints of patients, due to its influence on the self-esteem. It is known that it has a multifactorial cause and can be present in the excessive vertical growth of the maxilla, excessive labial contraction, short upper ...
David Costa MOREIRA, Francielle Silva POSSIDÔNIO, Fabio Silveira de SOUZA, Angela Mitie Otta KINOSHITA, Elcia Maria Varize SILVEIRA   +4 more
doaj   +1 more source

Botulism in Cattle: A Case Report of an Outbreak in Sardinia (Italy)

Animals, 2023
Clostridium botulinum is the main causative agent of botulism in humans and animals. The ingestion of the botulinum neurotoxin, usually types C and D, has been shown to produce disease (neurological symptoms) in most botulism cases in cattle.
Luigia Pinna, Annamaria Coccollone, Marcella Maxia, Luca Bano, Concetta Scalfaro, Daniela Mandas, Manuele Liciardi   +6 more
doaj   +1 more source

Exploring the functional domain and the target of the tetanus toxin light chain in neurohypophysial terminals [PDF]

, 1994
The tetanus toxin light chain blocks calcium induced vasopressin release from neurohypophysial nerve terminals. Here we show that histidine residue 233 within the putative zinc binding motif of the tetanus toxin light chain is essential for the ...
Binz, T., Dayanithi, G., Gratzl, Manfred, Höhne-Zell, B., Niemann, H., Stecher, B., Weller, U., Yamasaki, S.   +7 more
core   +1 more source

The effects of a sodium and a calcium channel blocker on lethality of mice injected with the yellow scorpion (Leiurus quinquestriatus) venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2005
Scorpion venom toxins generally produce similar effects by mainly acting on sodium channels, and to a lesser extent, on potassium, calcium, and chloride channels.
A. R. Al-Shanawani, A. J. Fatani, F. H. El-Sayed   +2 more
doaj   +1 more source

Soluble Epoxide Hydrolase and Brain Cholesterol Metabolism

Frontiers in Molecular Neuroscience, 2020
The bifunctional enzyme soluble epoxide hydrolase (sEH) is found in all regions of the brain. It has two different catalytic activities, each assigned to one of its terminal domains: the C-terminal domain presents hydrolase activity, whereas the N ...
Michelle Flores Domingues, Michelle Flores Domingues, Natalia Callai-Silva, Natalia Callai-Silva, Angela Regina Piovesan, Celia Regina Carlini, Celia Regina Carlini, Celia Regina Carlini   +7 more
doaj   +1 more source

In Vitro Effects of Paralytic Shellfish Toxins and Lytic Extracellular Compounds Produced by Alexandrium Strains on Hemocyte Integrity and Function in Mytilus edulis

Toxins, 2021
Harmful effects caused by the exposure to paralytic shellfish toxins (PSTs) and bioactive extracellular compounds (BECs) on bivalves are frequently difficult to attribute to one or the other compound group. We evaluate and compare the distinct effects of
Virginia Angélica Bianchi, Ulf Bickmeyer, Urban Tillmann, Bernd Krock, Annegret Müller, Doris Abele   +5 more
doaj   +1 more source

Botulinum toxins and fillers for treatment of the aging face

TNOA Journal of Ophthalmic Science and Research, 2017
We present a comprehensive review of how to best use neuro-toxins and fillers to rejuvenate the aging face. With modern neuro-toxins and fillers, it is now possible to achieve an improvement in the aging changes of young, middle-aged, and older patients.
Bhupendra C. K. Patel
doaj   +1 more source

Molecular Aspects of Secretory Granule Exocytosis by Neurons and Endocrine Cells [PDF]

, 1994
Neuronal communication and endocrine signaling are fundamental for integrating the function of tissues and cells in the body. Hormones released by endocrine cells are transported to the target cells through the circulation.
Ahnert-Hilger G., Ahnert-Hilger G., Bader M. F., Baumert M., Bittner M. A., Bittner M. A., Bittner M. A., Blasi J., Elferink L. A., Fischer G., Geppert M., Halpern J. L., Hess S. D., Jahn R., MANFRED GRATZL, Marqueze-Pouey B., McMahon H. T., Schiavo G., Schiavo G., Schiavo G., Schmidle T., Shirataki H., Shoji-Kasai Y., Stecher B., Thomas L., Trimble W. S., Walch-Solimena C., Wright J. F., Yoshida A.   +28 more
core   +1 more source

Widespread Evolution of Molecular Resistance to Snake Venom α-Neurotoxins in Vertebrates

Toxins, 2020
Venomous snakes are important subjects of study in evolution, ecology, and biomedicine. Many venomous snakes have alpha-neurotoxins (α-neurotoxins) in their venom.
Muzaffar A. Khan, D. Dashevsky, Harald M. I. Kerkkamp, D. Kordis, M. D. de Bakker, Roel M Wouters, Jory van Thiel, Bianca op den Brouw, F. Vonk, R. Kini, J. Nazir, Bryan G. Fry, Michael K. Richardson   +12 more
semanticscholar   +1 more source