Results 41 to 50 of about 77,752 (388)
Why Are Botulinum Neurotoxin-Producing Bacteria So Diverse and Botulinum Neurotoxins So Toxic?
Toxins, 2019 Botulinum neurotoxins (BoNTs) are the most lethal toxins among all bacterial, animal, plant and chemical poisonous compounds. Although a great effort has been made to understand their mode of action, some questions are still open.
B. Poulain, M. Popoff
semanticscholar +1 more source
The light chain of tetanus toxin inhibits calcium-dependent vasopressin release from permeabilized nerve endings [PDF]
, 1992 The effects of tetanus toxin and its light and heavy chain subunits on vasopressin release were investigated in digitonin-permeabilized neurosecretory nerve terminals isolated from the neural lobe of the rat pituitary gland.
Ahnert-Hilger, G. +5 more
core +1 more source
Scallop genome reveals molecular adaptations to semi-sessile life and neurotoxins
Nature Communications, 2017 Bivalve molluscs are descendants of an early-Cambrian lineage superbly adapted to benthic filter feeding. Adaptations in form and behavior are well recognized, but the underlying molecular mechanisms are largely unknown.
Yuli Li +40 more
semanticscholar +1 more source
Pharmaceuticals, 2020 Guanitoxin (GNT) is a potent neurotoxin produced by freshwater cyanobacteria that can cause the deaths of wild and domestic animals. Through reports of animal intoxication by cyanobacteria cells that produce GNT, this study aimed to investigate the bio ...
Kelly Afonsina Fernandes +3 more
doaj +1 more source
Behavioral Tests in Neurotoxin-Induced Animal Models of Parkinson’s Disease
Antioxidants, 2020 Currently, neurodegenerative diseases are a major cause of disability around the world. Parkinson’s disease (PD) is the second-leading cause of neurodegenerative disorder after Alzheimer’s disease.
E. Maruthi Prasad, Shih-Ya Hung
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Discovery of an Insect Neuroactive Helix Ring Peptide from Ant Venom
Toxins, 2023 Ants are among the most abundant terrestrial invertebrate predators on Earth. To overwhelm their prey, they employ several remarkable behavioral, physiological, and biochemical innovations, including an effective paralytic venom.
Valentine Barassé +19 more
doaj +1 more source
Neurotoxic Alkaloids: Saxitoxin and Its Analogs
Marine Drugs, 2010 Saxitoxin (STX) and its 57 analogs are a broad group of natural neurotoxic alkaloids, commonly known as the paralytic shellfish toxins (PSTs). PSTs are the causative agents of paralytic shellfish poisoning (PSP) and are mostly associated with marine ...
Troco K. Mihali +4 more
doaj +1 more source
Short Linear Motifs Characterizing Snake Venom and Mammalian Phospholipases A2
Toxins, 2021 Snake venom phospholipases A2 (PLA2s) have sequences and structures very similar to those of mammalian group I and II secretory PLA2s, but they possess many toxic properties, ranging from the inhibition of coagulation to the blockage of nerve ...
Caterina Peggion, Fiorella Tonello
doaj +1 more source
ATP Released by Injured Neurons Activates Schwann Cells [PDF]
, 2016 Injured nerve terminals of neuromuscular junctions (NMJs) can regenerate. This remarkable and complex response is governed by molecular signals that are exchanged among the cellular components of this synapse: motor axon nerve terminal (MAT ...
Cesare eMontecucco +8 more
core +2 more sources
Rapid Detection of Botulinum Neurotoxins—A Review
Toxins, 2019 A toxin is a poisonous substance produced within living cells or organisms. One of the most potent groups of toxins currently known are the Botulinum Neurotoxins (BoNTs).
R. Hobbs +3 more
semanticscholar +1 more source