Results 21 to 30 of about 7,882 (239)
Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications
Neurotoxins generally inhibit or promote the release of neurotransmitters or bind to receptors that are located in the pre- or post-synaptic membranes, thereby affecting physiological functions of synapses and affecting biological processes.
Kunming Zhou +4 more
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Guanitoxin (GNT) is a potent neurotoxin produced by freshwater cyanobacteria that can cause the deaths of wild and domestic animals. Through reports of animal intoxication by cyanobacteria cells that produce GNT, this study aimed to investigate the bio ...
Kelly Afonsina Fernandes +3 more
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Synthesis-Driven Stereochemical Assignment of Marine Polycyclic Ether Natural Products
Marine polycyclic ether natural products have gained significant interest from the chemical community due to their impressively huge molecular architecture and diverse biological functions.
Haruhiko Fuwa
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Scorpion venom toxins generally produce similar effects by mainly acting on sodium channels, and to a lesser extent, on potassium, calcium, and chloride channels.
A. R. Al-Shanawani +2 more
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Matrix-assisted laser-desorption time-of-flight (MALDI-TOF) mass spectrometry (MS) is a valuable high-throughput tool for peptide analysis. Liquid chromatography electrospray ionization (LC-ESI) tandem-MS provides sensitive and specific quantification of
Suzanne Kalb +8 more
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The noble false widow spider Steatoda nobilis originates from the Macaronesian archipelago and has expanded its range globally. Outside of its natural range, it may have a negative impact on native wildlife, and in temperate regions it lives in ...
John P. Dunbar +5 more
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Discovery of an Insect Neuroactive Helix Ring Peptide from Ant Venom
Ants are among the most abundant terrestrial invertebrate predators on Earth. To overwhelm their prey, they employ several remarkable behavioral, physiological, and biochemical innovations, including an effective paralytic venom.
Valentine Barassé +19 more
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Koenraad De Boulle,1 Nobutaka Furuyama,2 Izolda Heydenrych,3,4 Terrence Keaney,5 Alexander Rivkin,6 Vincent Wong,7 Michael Silberberg8 1Aalst Dermatology Clinic, Aalst, Belgium; 2Jiyugaoka Clinic, Medical Corporation, Tokyo, Japan; 3Cape Town Cosmetic ...
De Boulle K +6 more
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Short Linear Motifs Characterizing Snake Venom and Mammalian Phospholipases A2
Snake venom phospholipases A2 (PLA2s) have sequences and structures very similar to those of mammalian group I and II secretory PLA2s, but they possess many toxic properties, ranging from the inhibition of coagulation to the blockage of nerve ...
Caterina Peggion, Fiorella Tonello
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Scorpion Peptides and Ion Channels: An Insightful Review of Mechanisms and Drug Development
The Buthidae family of scorpions consists of arthropods with significant medical relevance, as their venom contains a diverse range of biomolecules, including neurotoxins that selectively target ion channels in cell membranes.
Lais Campelo Mendes +4 more
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