Results 21 to 30 of about 7,882 (239)

Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications

open access: yesToxins, 2022
Neurotoxins generally inhibit or promote the release of neurotransmitters or bind to receptors that are located in the pre- or post-synaptic membranes, thereby affecting physiological functions of synapses and affecting biological processes.
Kunming Zhou   +4 more
doaj   +1 more source

Availability of Guanitoxin in Water Samples Containing Sphaerospermopsis torques-reginae Cells Submitted to Dissolution Tests

open access: yesPharmaceuticals, 2020
Guanitoxin (GNT) is a potent neurotoxin produced by freshwater cyanobacteria that can cause the deaths of wild and domestic animals. Through reports of animal intoxication by cyanobacteria cells that produce GNT, this study aimed to investigate the bio ...
Kelly Afonsina Fernandes   +3 more
doaj   +1 more source

Synthesis-Driven Stereochemical Assignment of Marine Polycyclic Ether Natural Products

open access: yesMarine Drugs, 2021
Marine polycyclic ether natural products have gained significant interest from the chemical community due to their impressively huge molecular architecture and diverse biological functions.
Haruhiko Fuwa
doaj   +1 more source

The effects of a sodium and a calcium channel blocker on lethality of mice injected with the yellow scorpion (Leiurus quinquestriatus) venom

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2005
Scorpion venom toxins generally produce similar effects by mainly acting on sodium channels, and to a lesser extent, on potassium, calcium, and chloride channels.
A. R. Al-Shanawani   +2 more
doaj   +1 more source

Quantitative Mass Spectrometry for Bacterial Protein Toxins — A Sensitive, Specific, High-Throughput Tool for Detection and Diagnosis

open access: yesMolecules, 2011
Matrix-assisted laser-desorption time-of-flight (MALDI-TOF) mass spectrometry (MS) is a valuable high-throughput tool for peptide analysis. Liquid chromatography electrospray ionization (LC-ESI) tandem-MS provides sensitive and specific quantification of
Suzanne Kalb   +8 more
doaj   +1 more source

Venomics Approach Reveals a High Proportion of Lactrodectus-Like Toxins in the Venom of the Noble False Widow Spider Steatoda nobilis

open access: yesToxins, 2020
The noble false widow spider Steatoda nobilis originates from the Macaronesian archipelago and has expanded its range globally. Outside of its natural range, it may have a negative impact on native wildlife, and in temperate regions it lives in ...
John P. Dunbar   +5 more
doaj   +1 more source

Discovery of an Insect Neuroactive Helix Ring Peptide from Ant Venom

open access: yesToxins, 2023
Ants are among the most abundant terrestrial invertebrate predators on Earth. To overwhelm their prey, they employ several remarkable behavioral, physiological, and biochemical innovations, including an effective paralytic venom.
Valentine Barassé   +19 more
doaj   +1 more source

Considerations for the Use of Minimally Invasive Aesthetic Procedures for Facial Remodeling in Transgender Individuals

open access: yesClinical, Cosmetic and Investigational Dermatology, 2021
Koenraad De Boulle,1 Nobutaka Furuyama,2 Izolda Heydenrych,3,4 Terrence Keaney,5 Alexander Rivkin,6 Vincent Wong,7 Michael Silberberg8 1Aalst Dermatology Clinic, Aalst, Belgium; 2Jiyugaoka Clinic, Medical Corporation, Tokyo, Japan; 3Cape Town Cosmetic ...
De Boulle K   +6 more
doaj  

Short Linear Motifs Characterizing Snake Venom and Mammalian Phospholipases A2

open access: yesToxins, 2021
Snake venom phospholipases A2 (PLA2s) have sequences and structures very similar to those of mammalian group I and II secretory PLA2s, but they possess many toxic properties, ranging from the inhibition of coagulation to the blockage of nerve ...
Caterina Peggion, Fiorella Tonello
doaj   +1 more source

Scorpion Peptides and Ion Channels: An Insightful Review of Mechanisms and Drug Development

open access: yesToxins, 2023
The Buthidae family of scorpions consists of arthropods with significant medical relevance, as their venom contains a diverse range of biomolecules, including neurotoxins that selectively target ion channels in cell membranes.
Lais Campelo Mendes   +4 more
doaj   +1 more source

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