Results 21 to 30 of about 28,883 (156)
Short Linear Motifs Characterizing Snake Venom and Mammalian Phospholipases A2
Toxins, 2021 Snake venom phospholipases A2 (PLA2s) have sequences and structures very similar to those of mammalian group I and II secretory PLA2s, but they possess many toxic properties, ranging from the inhibition of coagulation to the blockage of nerve ...
Caterina Peggion, Fiorella Tonello
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Neurotoxins as Preclinical Models for Parkinson’s Disease [PDF]
, 2018 © 2018, Springer Science+Business Media, LLC, part of Springer Nature.Translational medicine is one of the major concerns in this century. While significant advances have been made with scientific knowledge, the translation of their promising results has
Segura Aguilar, Juan +1 more
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Journal of Venomous Animals and Toxins including Tropical Diseases, 2005 Scorpion venom toxins generally produce similar effects by mainly acting on sodium channels, and to a lesser extent, on potassium, calcium, and chloride channels.
A. R. Al-Shanawani +2 more
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S43 | NEUROTOXINS | Neurotoxicants Collection from Public Resources
, 2019 <p>This is the collection associated with list S43 NEUROTOXINS on the NORMAN Suspect List Exchange.</p> <p><a href="https://www.norman-network.com/?q=suspect-list-exchange">https://www.norman-network.com/?q=suspect-list-exchange ...
Schymanski, Emma +5 more
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Antipruritic Effects of Botulinum Neurotoxins [PDF]
, 2018 This review explores current evidence to demonstrate that botulinum neurotoxins (BoNTs) exert antipruritic effects. Both experimental and clinical conditions in which botulinum neurotoxins have been applied for pruritus relief will be presented and ...
Gazerani, Parisa; id_orcid +1 more
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Scorpion Peptides and Ion Channels: An Insightful Review of Mechanisms and Drug Development
Toxins, 2023 The Buthidae family of scorpions consists of arthropods with significant medical relevance, as their venom contains a diverse range of biomolecules, including neurotoxins that selectively target ion channels in cell membranes.
Lais Campelo Mendes +4 more
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Molecular Diversity and Isoform Evolution in Tityus obscurus Venom: Insights from Proteomic Analysis
ToxinsOver millions of years of evolution, natural selection has driven the specialization of predatory and defensive mechanisms in various animal species through the development of poisons and venoms.
Kemellyn Cristina Panchera +4 more
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Neurotoxins and neurotoxicity mechanisms. An overview [PDF]
, 2006 Neurotoxlns represent unique chemical tools, providing a means to 1) gain insight into cellular mechanisms of apopotosis and necrosis, 2) achieve a morphological template for studies otherwise unattainable, 3) specifically produce a singular phenotype of
Segura-Aguilar, Juan +4 more
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Presynaptic neurotoxins with enzymatic activities
, 2008 Toxins that alter neurotransmitter release from nerve terminals are of considerable scientific and clinical importance. Many advances were recently made in the understanding of their molecular mechanisms of action and use in human therapy. Here, we focus
Cesare Montecucco +3 more
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Neurotoxic Alkaloids: Saxitoxin and Its Analogs
Marine Drugs, 2010 Saxitoxin (STX) and its 57 analogs are a broad group of natural neurotoxic alkaloids, commonly known as the paralytic shellfish toxins (PSTs). PSTs are the causative agents of paralytic shellfish poisoning (PSP) and are mostly associated with marine ...
Troco K. Mihali +4 more
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