Results 71 to 80 of about 77,752 (388)
A critical hurdle in ant venom proteomic investigations is the lack of databases to comprehensively and specifically identify the sequence and function of venom proteins and peptides.
Samira R. Aili+13 more
doaj +1 more source
Clostridium botulinum Type E Toxins Bind to Caco-2 Cells by a Different Mechanism from That of Type A Toxins [PDF]
Cultured Clostridium botulinum strains produce progenitor toxins designated as 12S, 16S, and 19S toxins. The 12S toxin consists of a neurotoxin (NTX, 7S) and a non-toxic non-hemagglutinin (NTNH).
Ma, Shaobo+6 more
core +1 more source
Engineering of Botulinum Neurotoxins for Biomedical Applications
Botulinum neurotoxins (BoNTs) have been used as therapeutic agents in the clinical treatment of a wide array of neuromuscular and autonomic neuronal transmission disorders.
R. Webb
semanticscholar +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Amylase release from streptolysin O-permeabilized pancreatic acinar cells. Effects of Ca2+, guanosine 5'-[gamma-thio]triphosphate, cyclic AMP, tetanus toxin and botulinum A toxin [PDF]
The molecular requirements for amylase release and the intracellular effects of botulinum A toxin and tetanus toxin on amylase release were investigated using rat pancreatic acinar cells permeabilized with streptolysin O.
Ahnert-Hilger, G.+4 more
core
Outbreak of a neurotoxic side-gilled sea slug (Pleurobranchaea sp.) in Argentinian coasts [PDF]
Since 2009 we have been registering the outbreak of an unknown side-gilled sea slug of the genus Pleurobranchaea in coastal waters of Argentina, southwestern Atlantic Ocean.
Farias, Nahuel Emiliano+2 more
core +1 more source
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Occupational lead neurotoxicity: Improvement in behavioural effects after reduction of exposure. [PDF]
To evaluate critical exposure levels and the reversibility of lead neurotoxicity a group of lead exposed foundry workers and an unexposed reference population were followed up for three years.
Baker, E. L.+7 more
core +3 more sources
Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao+5 more
wiley +1 more source
Monitoring neurotoxins in industry: development of a neurobehavioral test battery [PDF]
Huguet Françoise. 104 - Elémens (Les) ou premières instructions de la jeunesse. In: , . Les Livres pour l'Enfance et la Jeunesse de Gutenberg à Guizot. Les collections de la Bibliothèque de l'Institut National de Recherche Pédagogique.
Baker, E. L.+5 more
core +2 more sources