Results 111 to 120 of about 556,811 (333)

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Mammalian Taste Bud Cells Utilize Extragemmal 5-Hydroxy-L-Tryptophan to Biosynthesize the Neurotransmitter Serotonin

Frontiers in Cellular Neuroscience, 2018
Serotonin or 5-hydroxytryptamine (5-HT) is an important neurotransmitter that is found in mammalian taste buds and can regulate the output of intragemmal signaling networks onto afferent nerve fibers.
Hong-Ru Pan, Miao Tian, Jian-Bo Xue, Song-Min Li, Xiao-Cui Luo, Xiao Huang, Zhen-Huang Chen, Liquan Huang, Liquan Huang   +8 more
doaj   +1 more source

The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43

, 2019
The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function and neuronal activity are largely unexplored.
Bansal, V., Bonn, S., Fornasiero, E., Fritsch, E., Gomes, L., Gärtner, A., Keihani, S., Klüver, V., Kügler, S., Mandad, S., Rahman, R., Rizzoli, S., Urlaub, H., Wren, J.   +13 more
core   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

[³H]spirperidol binding to brain neurotransmitter receptors [PDF]

, 1980
Raymond M. Withy, R. John Mayer, Philip G. Strange   +2 more
openalex   +1 more source

Flexible Sensor‐Based Human–Machine Interfaces with AI Integration for Medical Robotics

Advanced Robotics Research, EarlyView.
This review explores how flexible sensing technology and artificial intelligence (AI) significantly enhance human–machine interfaces in medical robotics. It highlights key sensing mechanisms, AI‐driven advancements, and applications in prosthetics, exoskeletons, and surgical robotics.
Yuxiao Wang, Zhipeng Jiang, Sun Hwa Kwon, Matthew Ibrahim, Alexander Dang, Lin Dong   +5 more
wiley   +1 more source

Editorial: Nongenomic influences of thyroid hormones and their metabolites in adults: a tribute to Mary B. Dratman

Frontiers in Endocrinology, 2023
Pradip K. Sarkar, Joseph V. Martin
doaj   +1 more source

DETERMINATION OF GAMMA - AMINOBUTYRIC ACID BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

Acta Medica Iranica, 1998
Gamma-aminobutyric acid is the main inhibitory amino acid neurotransmitter in several areas of the brain. Measurement of gamma-aminobutyric acid in the brain will help elucidate its metabolic rote and diagnostic value.
D. Qujeq
doaj  

Carbon microelectrodes for the measurement of neurotransmitters with fast-scan cyclic voltammetry: methodology and applications

Frontiers in Bioengineering and Biotechnology
Carbon microelectrodes (CMEs) have emerged as pivotal tools in the field of neurochemical sensing, enabling precise, real-time monitoring of neurotransmitters in both research and clinical contexts.
Nadiah Alyamni, Nadiah Alyamni, Jandro L. Abot, Alexander G. Zestos   +3 more
doaj   +1 more source

The organisation and functions of local Ca²⁺ signals [PDF]

, 2001
Calcium (Ca2+) is a ubiquitous intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation.
Berridge, Michael J., Bootman, Martin D., Lipp, Peter   +2 more
core