Roles of Beta2- and Beta3-Adrenoceptor Polymorphisms in Hypertension and Metabolic Syndrome
International Journal of Hypertension, 2010 Hypertension, diabetes mellitus (especially type 2 diabetes mellitus), metabolic syndrome and obesity are rapidly growing public health problems. Sympathetic nerve activation is observed in obesity, hypertension and diabetes mellitus, which have strong ...
Kazuko Masuo
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Global parameter search reveals design principles of the mammalian circadian clock [PDF]
, 2008 Background: Virtually all living organisms have evolved a circadian (~24 hour) clock that controls physiological and behavioural processes with exquisite precision throughout the day/night cycle.
AC Liu +46 more
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Relationships of Adrenoceptor Polymorphisms with Obesity
Journal of Obesity, 2011 Obesity, hypertension, and type 2 diabetes are rapidly growing public health problems. Heightened sympathetic nerve activity is a well-established observation in obesity, hypertension, and type 2 diabetes.
Kazuko Masuo, Gavin W. Lambert
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Frontiers in Neuroscience, 2018 This report provides a historical overview of research concerning the endogenous hallucinogen N, N-dimethyltryptamine (DMT), focusing on data regarding its biosynthesis and metabolism in the brain and peripheral tissues, methods and results for DMT ...
Steven A. Barker
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Neurotransmitters and Neuromodulators [PDF]
Acta geneticae medicae et gemellologiae, 1974 In the central nervous system, besides the neurotransmitters, the occurrence of substances which modify neuronal excitability has been proposed. Since their effect is a matter of modulating neuronal responsiveness, these substances may be called neuromodulators.Examples of neurotransmitters or putative neurotransmitters in the central nervous system ...
openaire +2 more sources
Quantitative Analysis Linking Inner Hair Cell Voltage Changes and Postsynaptic Conductance Change: A Modelling Study [PDF]
, 2015 This paper presents a computational model which estimates the postsynaptic conductance change of mammalian Type I afferent peripheral process when airborne acoustic waves impact on the tympanic membrane. A model of the human auditory periphery is used to
Drakakis, EM, Prokopiou, AN
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Single-Cell Transcriptomic Reveals Dual and Multi-Transmitter Use in Neurons Across Metazoans
Frontiers in Molecular Neuroscience, 2021 Neurotransmitter expression is widely used as a criterion for classifying neurons. It was initially thought that neurons express a single type of neurotransmitter, a phenomenon commonly recognized as Dale's principle: “one neuron, one transmitter ...
Clarisse Brunet Avalos +1 more
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Increased bradykinesia in Parkinson’s disease with increased movement complexity: elbow flexion-extension movements [PDF]
, 2008 The present research investigates factors contributing to bradykinesia in the control of simple and complex voluntary limb movement in Parkinson’s disease (PD) patients.
Geelen, J.A.G. +3 more
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Maturation of a central brain flight circuit in Drosophila requires Fz2/Ca2+ signaling
eLife, 2015 The final identity of a differentiated neuron is determined by multiple signaling events, including activity dependent calcium transients. Non-canonical Frizzled2 (Fz2) signaling generates calcium transients that determine neuronal polarity, neuronal ...
Tarjani Agrawal, Gaiti Hasan
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Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. [PDF]
, 2017 Glutamate is the dominant excitatory neurotransmitter in the brain, but under conditions of metabolic stress it can accumulate to excitotoxic levels.
Andreyev, Alexander Y +12 more
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