Neurotransmitters and Neuromodulators [PDF]
Acta geneticae medicae et gemellologiae, 1974 In the central nervous system, besides the neurotransmitters, the occurrence of substances which modify neuronal excitability has been proposed. Since their effect is a matter of modulating neuronal responsiveness, these substances may be called neuromodulators.Examples of neurotransmitters or putative neurotransmitters in the central nervous system ...
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Cholinergic suppression: A postsynaptic mechanism of long-term associative learning [PDF]
, 1986 Food avoidance learning in the mollusc Pleurobranchaea entails reduction in the responsiveness of key brain interneurons in the feeding neural circuitry, the paracerebral feeding command interneurons (PCNs), to the neurotransmitter acetylcholine (AcCho).
Davis, W. Jackson +5 more
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Cloning, expression, and localization of a rat brain high-affinity glycine transporter [PDF]
, 1992 A cDNA clone encoding a glycine transporter has been isolated from rat brain by a combined PCR and plaque-hybridization strategy. mRNA synthesized from this clone (designated GLYT1) directs the expression of sodium-and chloride-dependent, high-affinity ...
Brecha, Nicholas +4 more
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Single-Cell Transcriptomic Reveals Dual and Multi-Transmitter Use in Neurons Across Metazoans
Frontiers in Molecular Neuroscience, 2021 Neurotransmitter expression is widely used as a criterion for classifying neurons. It was initially thought that neurons express a single type of neurotransmitter, a phenomenon commonly recognized as Dale's principle: “one neuron, one transmitter ...
Clarisse Brunet Avalos +1 more
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Maturation of a central brain flight circuit in Drosophila requires Fz2/Ca2+ signaling
eLife, 2015 The final identity of a differentiated neuron is determined by multiple signaling events, including activity dependent calcium transients. Non-canonical Frizzled2 (Fz2) signaling generates calcium transients that determine neuronal polarity, neuronal ...
Tarjani Agrawal, Gaiti Hasan
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Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. [PDF]
, 2017 Glutamate is the dominant excitatory neurotransmitter in the brain, but under conditions of metabolic stress it can accumulate to excitotoxic levels.
Andreyev, Alexander Y +12 more
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A transsynaptic nanocolumn aligns neurotransmitter release to receptors
Nature, 2016 Synaptic transmission is maintained by a delicate, sub-synaptic molecular architecture, and even mild alterations in synapse structure drive functional changes during experience-dependent plasticity and pathological disorders. Key to this architecture is
A. Tang +5 more
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An in vivo biosensor for neurotransmitter release and in situ receptor activity. [PDF]
, 2010 Tools from molecular biology, combined with in vivo optical imaging techniques, provide new mechanisms for noninvasively observing brain processes. Current approaches primarily probe cell-based variables, such as cytosolic calcium or membrane potential ...
Griesbeck, Oliver +6 more
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Frontiers in Oncology, 2021 The incidence of head and neck squamous cell carcinoma (HNSC) is increasing year by year. The nerve is an important component of the tumor microenvironment, which has a wide range of cross-talk with tumor cells and immune cells, especially in highly ...
Jun Li +6 more
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Modeling Fault Propagation Paths in Power Systems: A New Framework Based on Event SNP Systems With Neurotransmitter Concentration [PDF]
, 2019 To reveal fault propagation paths is one of the most critical studies for the analysis of power system security; however, it is rather dif cult. This paper proposes a new framework for the fault propagation path modeling method of power systems based ...
Huang, Tao +6 more
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