Results 51 to 60 of about 303,476 (337)
Objective: To study the protective effects of polysaccharide from Polygonati rhizoma (PSP) on acute behavioral despair mice and the underlying mechanisms. Methods: A total of 60 ICR mice were randomly divided into the control group, the paroxetine group (
Zhen WEI+8 more
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Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction [PDF]
Synaptic dysfunction is widely thought to be a pathogenic precursor to neurodegeneration in Alzheimer’s disease (AD), and the extent of synaptic loss provides the best correlate for the severity of dementia in AD patients.
Ho, Angela+5 more
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Le DHA dans la neurotransmission
Long chain polyunsaturated fatty acids (PUFAs), particularly arachidonic acid and docosahexaenoic acid (DHA), are integral components of neural membrane phospholipids. DHA deficiency is associated with behavioural and neurophysiological disorders.
Lavialle Monique+5 more
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This research aimed to study the preventive and relieving outcomes of kiwi berry on constipation. The administration of kiwi berries to mice resulted in a significant increase in body weight gain of 148.2% compared to mice that were constipated.
Jiyue Zhang+10 more
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A receptor-based analysis of local ecosystems in the human brain. [PDF]
BackgroundAs a complex system, the brain is a self-organizing entity that depends on local interactions among cells. Its regions (anatomically defined nuclei and areas) can be conceptualized as cellular ecosystems, but the similarity of their functional ...
Janušonis, Skirmantas
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Neurotransmitter receptors on microglia
As the resident immune cells in the central nervous system, microglia have long been hypothesised to promote neuroinflammation and exacerbate neurotoxicity.
Huan Liu, R. Leak, Xiaoming Hu
semanticscholar +1 more source
Quantitative Analysis Linking Inner Hair Cell Voltage Changes and Postsynaptic Conductance Change: A Modelling Study [PDF]
This paper presents a computational model which estimates the postsynaptic conductance change of mammalian Type I afferent peripheral process when airborne acoustic waves impact on the tympanic membrane. A model of the human auditory periphery is used to
Drakakis, EM, Prokopiou, AN
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A Life of Neurotransmitters [PDF]
Development of scientific creativity is often tied closely to mentorship. In my case, two years with Julius Axelrod, the sum total of my research training, was transformative. My mentoring generations of graduate students and postdoctoral fellows has been as nurturing for me as it has been for them.
openaire +3 more sources
Membrane bridging by Munc13-1 is crucial for neurotransmitter release
Munc13-1 plays a crucial role in neurotransmitter release. We recently proposed that the C-terminal region encompassing the C1, C2B, MUN and C2C domains of Munc13-1 (C1C2BMUNC2C) bridges the synaptic vesicle and plasma membranes through interactions ...
B. Quade+9 more
semanticscholar +1 more source
The International Working Group on Neurotransmitter related Disorders (iNTD): A worldwide research project focused on primary and secondary neurotransmitter disorders [PDF]
INTRODUCTION: Neurotransmitters are chemical messengers that enable communication between the neurons in the synaptic cleft. Inborn errors of neurotransmitter biosynthesis, breakdown and transport are a group of very rare neurometabolic diseases ...
Cortès-Saladelafont, Elisenda+17 more
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