Results 51 to 60 of about 303,476 (337)

Protective Effects and Mechanism of Polysaccharide from Polygonati rhizoma on Behavioral Despair Mice

open access: yesShipin gongye ke-ji, 2022
Objective: To study the protective effects of polysaccharide from Polygonati rhizoma (PSP) on acute behavioral despair mice and the underlying mechanisms. Methods: A total of 60 ICR mice were randomly divided into the control group, the paroxetine group (
Zhen WEI   +8 more
doaj   +1 more source

Inactivation of presenilins causes pre-synaptic impairment prior to post-synaptic dysfunction [PDF]

open access: yes, 2010
Synaptic dysfunction is widely thought to be a pathogenic precursor to neurodegeneration in Alzheimer’s disease (AD), and the extent of synaptic loss provides the best correlate for the severity of dementia in AD patients.
Ho, Angela   +5 more
core   +1 more source

Le DHA dans la neurotransmission

open access: yesOléagineux, Corps gras, Lipides, 2007
Long chain polyunsaturated fatty acids (PUFAs), particularly arachidonic acid and docosahexaenoic acid (DHA), are integral components of neural membrane phospholipids. DHA deficiency is associated with behavioural and neurophysiological disorders.
Lavialle Monique   +5 more
doaj   +1 more source

The effect of kiwi berry (Actinidia arguta) on preventing and alleviating loperamide-induced constipation

open access: yesFood Innovation and Advances, 2023
This research aimed to study the preventive and relieving outcomes of kiwi berry on constipation. The administration of kiwi berries to mice resulted in a significant increase in body weight gain of 148.2% compared to mice that were constipated.
Jiyue Zhang   +10 more
doaj   +1 more source

A receptor-based analysis of local ecosystems in the human brain. [PDF]

open access: yes, 2017
BackgroundAs a complex system, the brain is a self-organizing entity that depends on local interactions among cells. Its regions (anatomically defined nuclei and areas) can be conceptualized as cellular ecosystems, but the similarity of their functional ...
Janušonis, Skirmantas
core   +1 more source

Neurotransmitter receptors on microglia

open access: yesStroke and vascular neurology, 2016
As the resident immune cells in the central nervous system, microglia have long been hypothesised to promote neuroinflammation and exacerbate neurotoxicity.
Huan Liu, R. Leak, Xiaoming Hu
semanticscholar   +1 more source

Quantitative Analysis Linking Inner Hair Cell Voltage Changes and Postsynaptic Conductance Change: A Modelling Study [PDF]

open access: yes, 2015
This paper presents a computational model which estimates the postsynaptic conductance change of mammalian Type I afferent peripheral process when airborne acoustic waves impact on the tympanic membrane. A model of the human auditory periphery is used to
Drakakis, EM, Prokopiou, AN
core   +3 more sources

A Life of Neurotransmitters [PDF]

open access: yesAnnual Review of Pharmacology and Toxicology, 2017
Development of scientific creativity is often tied closely to mentorship. In my case, two years with Julius Axelrod, the sum total of my research training, was transformative. My mentoring generations of graduate students and postdoctoral fellows has been as nurturing for me as it has been for them.
openaire   +3 more sources

Membrane bridging by Munc13-1 is crucial for neurotransmitter release

open access: yeseLife, 2019
Munc13-1 plays a crucial role in neurotransmitter release. We recently proposed that the C-terminal region encompassing the C1, C2B, MUN and C2C domains of Munc13-1 (C1C2BMUNC2C) bridges the synaptic vesicle and plasma membranes through interactions ...
B. Quade   +9 more
semanticscholar   +1 more source

The International Working Group on Neurotransmitter related Disorders (iNTD): A worldwide research project focused on primary and secondary neurotransmitter disorders [PDF]

open access: yes, 2016
INTRODUCTION: Neurotransmitters are chemical messengers that enable communication between the neurons in the synaptic cleft. Inborn errors of neurotransmitter biosynthesis, breakdown and transport are a group of very rare neurometabolic diseases ...
Cortès-Saladelafont, Elisenda   +17 more
core   +1 more source

Home - About - Disclaimer - Privacy