Results 131 to 140 of about 195,340 (251)

Copper (Cu²⁺) Inhibits Voltage-Dependent Ionic Currents While Enhancing Neurotransmitter Release in Bovine Chromaffin Cells. [PDF]

Pharmaceuticals (Basel)
Varea-Tierno V, Carretero VJ, Almodóvar MR, Hernández Campano J, Tejedor MA, de Pascual R, Hernández-Guijo JM.   +6 more
europepmc   +1 more source

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

Annals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera, Rossella Di Sapia, Greta Volpedo, Sneha Anand, Eray Sahin, Pasquale Baldassarre, Francesca Buffelli, Andrea Petretto, Chiara Lavarello, James D. Mills, Gabriele Cattaneo, Ilaria Craparotta, Eleonora Aronica, Antonella Riva, Pasquale Striano, Annamaria Vezzani, Teresa Ravizza   +16 more
wiley   +1 more source

Subthreshold electric fields bidirectionally modulate neurotransmitter release through axon polarization. [PDF]

Brain Stimul
Aberra AS, Miles MW, Hoppa MB.
europepmc   +1 more source

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

Annals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl, We Fong Siah, Jasmin Lope, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Alison Toomey, Jana Kleinerova, Peter Bede   +10 more
wiley   +1 more source

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang   +4 more
wiley   +1 more source

Using multiscale molecular dynamics simulations to explore the fusion machinery underlying neurotransmitter release. [PDF]

Q Rev Biophys
An D, Sharma S, Lindau M.
europepmc   +1 more source

GABA_B Receptors Tonically Inhibit Motoneurons and Neurotransmitter Release from Descending and Primary Afferent Fibers. [PDF]

Life (Basel), 2023
Delgado-Ramírez X, Alvarado-Cervantes NS, Jiménez-Barrios N, Raya-Tafolla G, Felix R, Martínez-Rojas VA, Delgado-Lezama R.   +6 more
europepmc   +1 more source

A lever hypothesis for Synaptotagmin-1 action in neurotransmitter release. [PDF]

Proc Natl Acad Sci U S A
Jaczynska K, Esser V, Xu J, Sari L, Lin MM, Rosenmund C, Rizo J.   +6 more
europepmc   +1 more source

Axonal neurotransmitter release in the regulation of myelination. [PDF]

Biosci Rep
Marshall-Phelps KLH, Almeida RG.
europepmc   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source