Results 71 to 80 of about 291,313 (279)

Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation

Advanced Functional Materials, EarlyView.
Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna, Katarina Gugujonovic, Manuela Schiek, Alessandro Bellapianta, Paul Werginz, Amelie Ziller, Markus Clark Scharber, Ahmad Salti, Matthias Bolz, Mihai Irimia‐Vladu, Günther Zeck   +10 more
wiley   +1 more source

Non-canonical Mechanisms of Presynaptic Kainate Receptors Controlling Glutamate Release

Frontiers in Molecular Neuroscience, 2018
A metabotropic modus operandi for kainate receptors (KARs) was first discovered in 1998 modulating GABA release. These receptors have been also found to modulate glutamate release at different synapses in several brain regions. Mechanistically, a general
José V. Negrete-Díaz, José V. Negrete-Díaz, Talvinder S. Sihra, Gonzalo Flores, Antonio Rodríguez-Moreno   +4 more
doaj   +1 more source

A Van der Waals Optoelectronic Synapse with Tunable Positive and Negative Post‐Synaptic Current for Highly Accurate Spiking Neural Networks

Advanced Functional Materials, EarlyView.
A van der Waals optoelectronic synaptic device based on a ReS2/WSe2 heterostructure and oxygen‐treated h‐BN is presented, which enables both positive and negative PSCs through photocarrier polarity reversal. Bidirectional plasticity arises from gate‐tunable band bending and charge trapping‐induced quasi‐doping.
Hyejin Yoon, Soeun Park, Yeong Kwon Kim, Juhwan Baek, Ki Han Kim, Seongil Yun, Hyeonchang Son, Jeongeun Choi, Byung Chul Jang, Dong‐Ho Kang   +9 more
wiley   +1 more source

Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse

Frontiers in Molecular Neuroscience
IntroductionRecently developed fluorescent neurotransmitter indicators have enabled direct measurements of neurotransmitter in the synaptic cleft. Precise optical measurements of neurotransmitter release may be used to make inferences about presynaptic ...
Paul Jakob Habakuk Hain, Paul Jakob Habakuk Hain, Tobias Moser, Tobias Moser   +3 more
doaj   +1 more source

Targeting light-gated chloride channels to neuronal somatodendritic domain reduces their excitatory effect in the axon

eLife, 2018
Light-gated chloride channels are emerging as promising optogenetic tools for inhibition of neural activity. However, their effects depend on the transmembrane chloride electrochemical gradient and may be complex due to the heterogeneity of this gradient
Jessica E Messier, Hongmei Chen, Zhao-Lin Cai, Mingshan Xue   +3 more
doaj   +1 more source

The evolution and comparative neurobiology of endocannabinoid signalling [PDF]

, 2012
CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A., Maurice R. Elphick, Montell C., Soderstrom K., Soderstrom K.   +4 more
core   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

Molecular mechanisms that stabilize short term synaptic plasticity during presynaptic homeostatic plasticity. [PDF]

, 2018
Presynaptic homeostatic plasticity (PHP) compensates for impaired postsynaptic neurotransmitter receptor function through a rapid, persistent adjustment of neurotransmitter release, an effect that can exceed 200%.
Davis, Graeme W, Genç, Özgür, Ortega, Jennifer M   +2 more
core   +1 more source

Enhancing Synaptic Plasticity and Multistate Retention of Organic Neuromorphic Devices Using Anion‐Excessive Gel Electrolyte

Advanced Functional Materials, EarlyView.
Anion‐excessive gel‐based organic synaptic transistors (AEG‐OSTs) that can maintain electrical neutrality are developed to enhance synaptic plasticity and multistate retention. Key improvement is attributed to the maintenance of electrical neutrality in the electrolyte even after electrochemical doping, which reduces the Coulombic force acting on ...
Yousang Won, Jeongwoo Lee, Hyunwook Kim, Joon Hak Oh   +3 more
wiley   +1 more source

The role of the neuromodulator adenosine in alcohols actions. [PDF]

, 1997
The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters.
Diamond, Ivan, Dohrman, D, Gordon, A
core