Results 21 to 30 of about 4,508,815 (293)

In vitro neuroprotective effects of ciliary neurotrophic factor on dorsal root ganglion neurons with glutamate-induced neurotoxicity

Neural Regeneration Research, 2017
Ciliary neurotrophic factor has neuroprotective effects mediated through signal transducer and Janus kinase (JAK) 2/activator of transcription 3 (STAT3) and phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathways.
Shu-yun Wen, Ai-min Li, Kuan-qing Mi, Rui-zheng Wang, Hao Li, Hua-xiang Liu, Yi Xing   +6 more
doaj   +1 more source

Glial cell line-derived neurotrophic factor effects on dental pulp cells and osteoblast-like cells [PDF]

, 2012
Glial cell line-derived neurotrophic factor (GDNF) is a growth factor promoting survival, proliferation and differentiation of neural crest cells. Neural crest cells play an important role within mesenchymal tissues during dental pulp and calvarial bone ...
Gale, Zoe
core   +7 more sources

Physical exercise during encoding improves vocabulary learning in young female adults [PDF]

, 2013
Acute physical activity has been repeatedly shown to improve various cognitive functions. However, there have been no investigations comparing the effects of exercise during verbal encoding versus exercise prior to encoding on long-term memory ...
Martin Reuter, Schmidt-Kassow, Maren, Reuter, Martin, Winfried Banzer, Jochen Kaiser, Deusser, Marie, Marie Deusser, Christian Thiel, Montag, Christian, Kaiser, Jochen, Thiel, Christian, Maren Schmidt-Kassow, Sascha Otterbein, Otterbein, Sascha, Christian Montag, Banzer, Winfried, Banzer Winfried, Thiel Christian, Reuter Martin, Schmidt-Kassow Maren, Deusser Marie, Montag Christian, Otterbein Sascha, Kaiser Jochen   +23 more
core   +2 more sources

Grafts of Fibroblasts Genetically Modified to Secrete Ngf, Bdnf, Nt-3, or Basic Fgf Elicit Differential Responses in the Adult Spinal Cord

Cell Transplantation, 1996
Neuronal and axonal responses to neurotrophic factors in the developing spinal cord have been relatively well characterized, but little is known about adult spinal responses to neurotrophic factors.
Yasushi Nakahara, Fred H. Gage, Mark H. Tuszynski   +2 more
doaj   +1 more source

Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy

Neural Regeneration Research, 2017
Neurotrophic factors comprise essential secreted proteins that have several functions in neural and non-neural tissues, mediating the development, survival and maintenance of peripheral and central nervous system. Therefore, neurotrophic factor issue has
Tuane Bazanella Sampaio, Anne Suely Savall, Maria Eduarda Ziani Gutierrez, Simone Pinton   +3 more
doaj   +1 more source

Acute effects of two different work-to-rest ratio of high-intensity interval training on brain-derived neurotrophic factor in untrained young men

Frontiers in Physiology, 2022
Background: Aerobic exercise could produce a positive effect on the brain by releasing brain-derived neurotrophic factor (BDNF). In untrained healthy humans there seems to be a linear correlation between exercise duration and the positive effect of acute
Kegang Zhao, Zhongyi Hu, Tao Wang, Lei Tian, Maoye Wang, Ruijiang Liu, Chongwen Zuo, Wang Jihua   +7 more
doaj   +1 more source

MANF: A New Player in the Control of Energy Homeostasis, and Beyond

Frontiers in Physiology, 2018
All human behaviors, including the control of energy homeostasis, are ultimately mediated by neuronal activities in the brain. Neurotrophic factors represent a protein family that plays important roles in regulating neuronal development, function, and ...
Su Yang, Shihua Li, Xiao-Jiang Li
doaj   +1 more source

Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2 [PDF]

, 2006
FGF-2, a potent multifunctional and neurotrophic growth factor, is widely expressed in the brain and upregulated in cerebral ischemia. Previous studies have shown that intraventricularly or systemically administered FGF-2 reduces the size of cerebral ...
Kiprianova, Irina, Dono, Rosanna, Schindowski, Katharina, Krause, Sonja, Bohlen und Halbach, Oliver von, Schwaninger, Markus, Unsicker, Klaus   +6 more
core   +1 more source

Long-term gene therapy causes transgene-specific changes in the morphology of regenerating retinal ganglion cells [PDF]

, 2012
Recombinant adeno-associated viral (rAAV) vectors can be used to introduce neurotrophic genes into injured CNS neurons, promoting survival and axonal regeneration.
Rodger Jennifer, Hellström Mats, Alan R Harvey, Jennifer Rodger, Mats Hellström, Hellström, M., Robertson, D., Harvey, A.R., Donald Robertson, Drummond Eleanor S., Harvey Alan R., Eleanor S Drummond, Rodger, J., Drummond, E.S., Robertson Donald   +14 more
core   +2 more sources

Acute strength exercise and the involvement of small or large muscle mass on plasma brain-derived neurotrophic factor levels

Clinics, 2010
OBJECTIVE: Blood neurotrophins, such as the brain-derived neurotrophic factor, are considered to be of great importance in mediating the benefits of physical exercise.
Paulo Roberto Correia, Aline Pansani, Felipe Machado, Marilia Andrade, Antonio Carlos da Silva, Fulvio Alexandre Scorza, Esper Abrão Cavalheiro, Ricardo Mario Arida   +7 more
doaj   +1 more source