Results 31 to 40 of about 4,508,815 (293)
The potential of bone morphogenetic protein 2 as a neurotrophic factor for Parkinson\u27s disease [PDF]
, 2020 Parkinson\u27s disease is the second most common neurodegenerative disorder; it affects 1% of the population over the age of 65. The number of people with Parkinson\u27s disease is set to rapidly increase due to changing demographics and there is an ...
O\u27Keeffe, Gerard W. +3 more
core
, 1999 The development of the retinogeniculate pathway or the geniculocortical pathway, or both, occurs either before birth or before eye opening in many species.
Shadbolt, N. R +3 more
core +2 more sources
Neurotrophic keratitis after penetrating keratoplasty for lattice dystrophy
American Journal of Ophthalmology Case Reports, 2021 Purpose: To report clinical outcomes of a patient with unilateral neurotrophic keratitis following penetrating keratoplasty for lattice dystrophy treated with topical recombinant human nerve growth factor.
Larissa Gouvea +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Brain Derived Neurotrophic Factor
, 2007 Brain-derived neurotrophic factor (BDNF) was originally identified as a factor that promoted survival of cultured embryonic chick sensory neurons .... © 2007 Elsevier Inc. All rights reserved.
David Middlemas, Middlemas, David
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali +4 more
wiley +1 more source
Tandem Repeat Peptide Strategy for the Design of Neurotrophic Factor Mimetics
, 2008 Neurotrophic factors comprise a broad family of secreted proteins that have growth promoting, survival promoting and differentiation inducing activities.
Doherty, Patrick +4 more
core +5 more sources
MoleculesMicroglia, the brain immune cells, support neurons by producing several established neurotrophic molecules including glial cell line-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF).
Kennedy R. Wiens +3 more
doaj +1 more source