Neurotrophic factors and corneal nerve regeneration [PDF]
The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Marta Sacchetti, Alessandro Lambiase
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Effects of Exercise Training on Neurotrophic Factors and Subsequent Neuroprotection in Persons with Multiple Sclerosis—A Systematic Review and Meta-Analysis [PDF]
Background: Evidence indicates that exercise holds the potential to counteract neurodegeneration experienced by persons with multiple sclerosis (pwMS), which is in part believed to be mediated through increases in neurotrophic factors. There is a need to
Mette D. Diechmann+5 more
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The Role of Metals in the Neuroregenerative Action of BDNF, GDNF, NGF and Other Neurotrophic Factors [PDF]
Mature neurotrophic factors and their propeptides play key roles ranging from the regulation of neuronal growth and differentiation to prominent participation in neuronal survival and recovery after injury.
Vincenzo Giuseppe Nicoletti+4 more
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Mimicking the neurotrophic factor profile of embryonic spinal cord controls the differentiation potential of spinal progenitors into neuronal cells. [PDF]
Recent studies have indicated that the choice of lineage of neural progenitor cells is determined, at least in part, by environmental factors, such as neurotrophic factors.
Masaya Nakamura+4 more
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Sustained delivery of neurotrophic factors to treat spinal cord injury
Acute spinal cord injury (SCI) is a devastating condition that results in tremendous physical and psychological harm and a series of socioeconomic problems.
Aikeremujiang Muheremu+4 more
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Neurotrophic factors comprise essential secreted proteins that have several functions in neural and non-neural tissues, mediating the development, survival and maintenance of peripheral and central nervous system. Therefore, neurotrophic factor issue has
Tuane Bazanella Sampaio+3 more
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Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central nervous system and have been shown to play crucial roles in regulating both normal and disease states.
Safak Er+2 more
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Neurotrophic factors and their effects in the treatment of multiple sclerosis
Neurotrophins are small molecules of polypeptides, which include nerve growth factor (NGF) family, glial cell line-derived neurotrophic factor (GDNF) family ligands, and neuropoietic cytokines. These factors have an important role in neural regeneration,
Shahnaz Razavi+5 more
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Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand ? [PDF]
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results in progressive loss of motoneurons, motor weakness and death within 3-5 years after disease onset.
Alexandre Henriques+4 more
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Depression, Neuroplasticity and Neurotrophic Factors [PDF]
Depression is a common psychiatric disorder. There is still very little known about the neurobiological alterations that underlie the pathophysiology of depression.
Cengiz Akkaya+3 more
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