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Neurotrophic Factors in Health and Disease [PDF]
Cells, 2022 Neurotrophic factors, including neurotrophins and neuropeptides, are secreted proteins that regulate the survival, development, and physiological functions of neurons in both the central and peripheral nervous systems [...]
Cinzia Severini
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Neurotrophic factors in multiple sclerosis [PDF]
Frontiers in ImmunologySmoldering inflammation and neurodegeneration, primarily driven by intraparenchymal immune cell activation and glial dysfunction, remains a major therapeutic challenge in Multiple Sclerosis (MS) and contributes largely to disability progression.
Fabian Güner +3 more
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Neurotrophic factors and corneal nerve regeneration [PDF]
Neural Regeneration Research, 2017 The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination.
Marta Sacchetti, Alessandro Lambiase
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Neurotrophic factors in the porcine ovary: Their effects on follicular growth, oocyte maturation, and developmental competence [PDF]
Frontiers in Veterinary Science, 2022 Pigs are cost-effective industrial animals because they produce a large number of offspring and have shorter rebreeding intervals compared with other animals, such as non-human primates.
Mirae Kim +4 more
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The Role of Metals in the Neuroregenerative Action of BDNF, GDNF, NGF and Other Neurotrophic Factors [PDF]
Biomolecules, 2022 Mature neurotrophic factors and their propeptides play key roles ranging from the regulation of neuronal growth and differentiation to prominent participation in neuronal survival and recovery after injury.
Vincenzo Giuseppe Nicoletti +4 more
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Neurotrophic basis to the pathogenesis of depression and phytotherapy
Frontiers in Pharmacology, 2023 Depression is a major neuropsychiatric disease that considerably impacts individuals’ psychosocial function and life quality. Neurotrophic factors are now connected to the pathogenesis of depression, while the definitive neurotrophic basis remains ...
Huiqin Wang +6 more
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Siberian Journal of Life Sciences and Agriculture, 2023 Understanding the metabolic pathways of regulation and interaction of neurotrophic factors is interesting from the point of view of discussing neurotrophic factors as biological markers reflecting the dynamics and effectiveness of the rehabilitation ...
Elizaveta S. Ageeva +6 more
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Brain Sciences, 2021 Background: Evidence indicates that exercise holds the potential to counteract neurodegeneration experienced by persons with multiple sclerosis (pwMS), which is in part believed to be mediated through increases in neurotrophic factors. There is a need to
Mette D. Diechmann +5 more
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Ciliary neurotrophic factor [PDF]
Journal of Neurobiology, 1994 AbstractCiliary neurotrophic factor (CNTF) was first identified and partially purified from embryonic chick eye tissues. Subsequently, it was shown that CNTF is also present in large amounts in sciatic nerves of adult rats and rabbits, which led to its final purification and cloning. CNTF is not secreted by the classical secretory pathway involving the
Yoshihiro Arakawa +13 more
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Melatonin: A Neurotrophic Factor?
Molecules, 2022 Melatonin, N-acetyl-5-hydroxytryptamine, is a hormone that synchronizes the internal environment with the photoperiod. It is synthesized in the pineal gland and greatly depends on the endogenous circadian clock located in the suprachiasmatic nucleus and the retina’s exposure to different light intensities.
Armida Miranda-Riestra +5 more
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