Results 1 to 10 of about 127,831 (178)

Neurotrophic factors in multiple sclerosis [PDF]

Frontiers in Immunology
Smoldering inflammation and neurodegeneration, primarily driven by intraparenchymal immune cell activation and glial dysfunction, remains a major therapeutic challenge in Multiple Sclerosis (MS) and contributes largely to disability progression.
Fabian Güner, Fabian Güner, Veit Rothhammer, Veit Rothhammer   +3 more
doaj   +2 more sources

Neurotrophic Factors in Health and Disease [PDF]

Cells, 2022
Neurotrophic factors, including neurotrophins and neuropeptides, are secreted proteins that regulate the survival, development, and physiological functions of neurons in both the central and peripheral nervous systems [...]
Cinzia Severini
doaj   +2 more sources

Inflammatory Biomarkers and Neurotrophic Factors in Preterm Newborns as Predictors of Motor Development: A Systematic Review [PDF]

Pediatric Reports
Background/Objectives: Preterm newborns (NBs) are at increased risk of motor developmental impairments. Evidence on inflammatory and neurotrophic biomarkers measured in the neonatal period as predictors of motor outcomes is scarce and heterogeneous. This
Letícia Silva Gabriel, Vicente Donisete Ferreira Júnior, Marina Ornelas Anastácia Pereira, Dayanne Gabriela de Melo Marques, Virgínia Mendes Russo Vallejos, Melina Barros-Pinheiro   +5 more
doaj   +2 more sources

Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 2: Where do we stand and where must we go next?

Neurobiology of Disease, 2017
The therapeutic potential of neurotrophic factors has been recognized for decades, with clinical trials in human neurodegenerative diseases extending back at least 25 years.
Raymond T. Bartus, Eugene M. Johnson, Jr.   +1 more
doaj   +2 more sources

Priming Canine Adipose Tissue-Derived Mesenchymal Stem Cells with CBD-Rich Cannabis Extract Modulates Neurotrophic Factors Expression Profile. [PDF]

Vet Sci
Perino VS, Ferreira LVO, Kamura BDC, Chimenes ND, Olbera AVG, Pereira TT, Braz AMM, Golim MA, Carvalho M, Amorim RM.   +9 more
europepmc   +3 more sources

Neurotrophic basis to the pathogenesis of depression and phytotherapy

Frontiers in Pharmacology, 2023
Depression is a major neuropsychiatric disease that considerably impacts individuals’ psychosocial function and life quality. Neurotrophic factors are now connected to the pathogenesis of depression, while the definitive neurotrophic basis remains ...
Huiqin Wang, Huiqin Wang, Yantao Yang, Gang Pei, Zhenzhen Wang, Naihong Chen, Naihong Chen   +6 more
doaj   +1 more source

FEATURES OF METABOLISM AND THE POTENTIAL ROLE OF NEUROTROPHIC FACTORS OF THE BRAIN IN THE REHABILITATION PROCESS

Siberian Journal of Life Sciences and Agriculture, 2023
Understanding the metabolic pathways of regulation and interaction of neurotrophic factors is interesting from the point of view of discussing neurotrophic factors as biological markers reflecting the dynamics and effectiveness of the rehabilitation ...
Elizaveta S. Ageeva, Larisa L. Korsunskaya, Natalia V. Larina, Elena A. Biryukova, Lyubov A. Chuprina, Anna K. Gurtovaya, Liliia S. Orekhova   +6 more
doaj   +1 more source

Neurotrophic factors in the porcine ovary: Their effects on follicular growth, oocyte maturation, and developmental competence

Frontiers in Veterinary Science, 2022
Pigs are cost-effective industrial animals because they produce a large number of offspring and have shorter rebreeding intervals compared with other animals, such as non-human primates.
Mirae Kim, Mirae Kim, Sang-Hwan Hyun, Sang-Hwan Hyun, Sang-Hwan Hyun   +4 more
doaj   +1 more source

Effects of Exercise Training on Neurotrophic Factors and Subsequent Neuroprotection in Persons with Multiple Sclerosis—A Systematic Review and Meta-Analysis

Brain Sciences, 2021
Background: Evidence indicates that exercise holds the potential to counteract neurodegeneration experienced by persons with multiple sclerosis (pwMS), which is in part believed to be mediated through increases in neurotrophic factors. There is a need to
Mette D. Diechmann, Evan Campbell, Elaine Coulter, Lorna Paul, Ulrik Dalgas, Lars G. Hvid   +5 more
doaj   +1 more source

The Role of Metals in the Neuroregenerative Action of BDNF, GDNF, NGF and Other Neurotrophic Factors

Biomolecules, 2022
Mature neurotrophic factors and their propeptides play key roles ranging from the regulation of neuronal growth and differentiation to prominent participation in neuronal survival and recovery after injury.
Vincenzo Giuseppe Nicoletti, Krisztián Pajer, Damiano Calcagno, Gholam Pajenda, Antal Nógrádi   +4 more
doaj   +1 more source