Results 51 to 60 of about 176,376 (142)
5-HT2A mediated plasticity as a target in major depression: a narrative review connecting the dots from neurobiology to cognition and psychology [PDF]
arXiv, 2020 As the world's first primary morbidity factor, depression has a considerable impact on both an individual as well as a societal level. despite their discovery several decades ago, classical antidepressants have been shown to provide limited benefits against this condition.
arxiv
Brain Sciences, 2019 (1) Background: Dimethylfumarate (DMF) has been approved for the treatment of relapsing remitting multiple sclerosis. However, the mode of action of DMF and its assumed active primary metabolite monomethylfumarate (MMF) is still not fully understood ...
Kaweh Pars +8 more
doaj +1 more source
Cell & Bioscience, 2021 Neuropeptide Y (NPY), one of the most abundant neuropeptides in the body, is widely expressed in the central and peripheral nervous systems and acts on the cardiovascular, digestive, endocrine, and nervous systems.
Yan Zhang +6 more
doaj +1 more source
Neurotrophic Factor Levels in Preterm Infants: A Systematic Review and Meta-Analysis
Frontiers in Neurology, 2021 Objectives: Through a systematic review and meta-analysis of the literature we aimed to compare the levels of BDNF, NGF, NT-3, NT-4, and GDNF between human term and preterm infants, and investigate factors implicated in the variability of effect size ...
Francieli Cristina Krey +10 more
doaj +1 more source
Impact of neurotrophic factors combination therapy on retinitis pigmentosa
Journal of International Medical Research, 2020 Objective We aimed to determine the location of neurotrophic receptors tropomyosin receptor kinase (Trk)B, TrkC, and ciliary neurotrophic factor receptor (CNTFR)α in the retina of retinal degeneration ( rd ) mice and to explore the dynamic changes of B ...
Xiaobei Yin +4 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Elaphuri Davidiani Cornu (EDC) is the natural shedding horn of Elaphurus davidiauus Millne-Edwards that was used by people in ancient China for maintaining physical and mental health.
Yue Zhu +11 more
doaj +1 more source
Neurotrophic factors and hippocampal activity in PTSD. [PDF]
PLoS ONE, 2018 Although numerous studies have investigated the neurotrophic factors and hippocampal activity in posttraumatic stress disorder (PTSD) separately each other, it is unclear whether an association between neurotrophic factors and hippocampal activity is ...
Ümit Tural +5 more
doaj +1 more source
Early reduced dopaminergic tone mediated by D3 receptor and dopamine transporter in absence epileptogenesis [PDF]
Epilepsia, 2019, 60 (10), pp.2128-2140Abstract Objective In Genetic Absence Epilepsy Rats From Strasbourg ( GAERS s), epileptogenesis takes place during brain maturation and correlates with increased mRNA expression of D3 dopamine receptors (D3R). Whether these alterations are the consequence of seizure repetition or contribute to the development of epilepsy remains to be clarified.
arxiv +1 more source
Neurotrophic Factors Protect the Intestinal Barrier from Rotavirus Insult in Mice
mBio, 2020 Increased intestinal permeability has been proposed as a mechanism of rotavirus-induced diarrhea. Studies with humans and mice have, however, shown that rotavirus leaves intestinal permeability unaffected or even reduced during diarrhea, in contrast to ...
Marie Hagbom +9 more
doaj +1 more source
Activity-dependent self-wiring is a basis of structural plastisity in neural networks [PDF]
arXiv, 2006 Dynamical wiring and rewiring in neural networks are carried out by activity-dependent growth and retraction of axons and dendrites, guided by gudance molecules, released by target cells. Experience-dependent structural changes in cortical microcurcuts lead to changes in activity, i.e. to changes in information encoded.
arxiv