Results 61 to 70 of about 176,376 (142)
Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand ?
Frontiers in Neuroscience, 2010 Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results in progressive loss of motoneurons, motor weakness and death within 3-5 years after disease onset.
Alexandre Henriques +4 more
doaj +1 more source
Spatial embedding of neuronal trees modeled by diffusive growth [PDF]
arXiv, 2006 The relative importance of the intrinsic and extrinsic factors determining the variety of geometric shapes exhibited by dendritic trees remains unclear. This question was addressed by developing a model of the growth of dendritic trees based on diffusion-limited aggregation process.
arxiv
MoleculesMicroglia, the brain immune cells, support neurons by producing several established neurotrophic molecules including glial cell line-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF).
Kennedy R. Wiens +3 more
doaj +1 more source
Dynamic Image-Based Modelling of Kidney Branching Morphogenesis [PDF]
arXiv, 2013 Kidney branching morphogenesis has been studied extensively, but the mechanism that defines the branch points is still elusive. Here we obtained a 2D movie of kidney branching morphogenesis in culture to test different models of branching morphogenesis with physiological growth dynamics. We carried out image segmentation and calculated the displacement
arxiv
NEUROTROPHIC EFFECTS OF ETIFOXINE
Неврология, нейропсихиатрия, психосоматика, 2016 Higher anxiety results in the decreased levels of various neurotrophic factors and enkephalins and in impaired production of proinflammatory cytokines. The anxiolytic etifoxine is used to treat anxiety states and adjustment disorders. Etifoxine modulates
I. Yu. Torshin +4 more
doaj +1 more source
Neural Regeneration Research, 2015 Chemically extracted acellular nerve allografts loaded with brain-derived neurotrophic factor-transfected or ciliary neurotrophic factor-transfected bone marrow mesenchymal stem cells have been shown to repair sciatic nerve injury better than chemically ...
Yan-ru Zhang +6 more
doaj +1 more source
Trajectory Networks and Their Topological Changes Induced by Geographical Infiltration [PDF]
arXiv, 2008 In this article we investigate the topological changes undergone by trajectory networks as a consequence of progressive geographical infiltration. Trajectory networks, a type of knitted network, are obtained by establishing paths between geographically distributed nodes while following an associated vector field.
arxiv
The effect of neurotrophic factors in multiple sclerosis treatment: A review
مجله دانشگاه علوم پزشکی گرگان, 2019 Multiple sclerosis (MS) is a chronic and multiphasic autoimmune disease which affecting the nervous system. Recently, neurotrophic factor secreting cells have been proposed as one of the best sources for cell therapy in MS disease. Therefore, this review
Nazem Ghasemi
doaj
Human Genome data analyzed by an evolutionary method suggests a decrease in cerebral protein-synthesis rate as cause of schizophrenia and an increase as antipsychotic mechanism [PDF]
arXiv, 2001 The Human Genome Project (HGP) provides researchers with the data of nearly all human genes and the challenge to use this information for elucidating the etiology of common disorders. A secondary Darwinian method was applied to HGP and other research data to approximate and possibly unravel the etiology of schizophrenia.
arxiv
The Robust Kernel Association Test [PDF]
arXiv, 2019 Testing the association between SNP effects and a response is a common task. Such tests are often carried out through kernel machine methods based on least squares, such as the Sequence Kernel Association Test (SKAT). However, these least squares procedures assume a normally distributed response, which is often violated. Other robust procedures such as
arxiv