Results 91 to 100 of about 38,429 (260)

Neurotrophin-4/5 is a mammalian-specific survival factor for distinct populations of sensory neurons [PDF]

, 1993
Alun M. Davies, Antony Horton, LE Burton, Charles H. Schmelzer, Richard Vandlen, Arnon Rosenthal   +5 more
openalex   +1 more source

The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases

Cell Proliferation, EarlyView.
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin, Libo Nie, Yan Deng, Ghulam Jilany Khana, Nongyue He   +4 more
wiley   +1 more source

Short- and Long-Term Effects of Subchronic Stress Exposure in Male and Female Brain-Derived Neurotrophic Factor Knock-In Val66Met Mice

Biology
Stress is an important risk factor for the onset of anxiety and depression. The ability to cope with stressful events varies among different subjects, probably depending on different genetic variants, sex and previous life experiences.
Fernando Antonio Costa Xavier, Silvia Stella Barbieri, Maurizio Popoli, Alessandro Ieraci   +3 more
doaj   +1 more source

Subpoblaciones neuronales presentes en el ganglio de la raíz dorsal

Biomédica: revista del Instituto Nacional de Salud, 2000
La función principal de las neuronas del ganglio de la raiz dorsal (GRD) es transmitir la información sensorial desde la periferia hasta el sistema nervioso central.
Marlén Martínez, Niyibi Y. Quiroga, Jaime E. Castellanos, Hernán Hurtado   +3 more
doaj   +1 more source

Purification and characterisation of a brain‐derived neurotrophic factor/ neurotrophin‐3 (BDNF/NT‐3) heterodimer [PDF]

, 1994
Stefan Jungbluth, Karen A. Bailey, Yves‐Alain Barde   +2 more
openalex   +1 more source

In vitro models of valproic acid to assess neurodevelopmental toxicity: A scoping review

Epilepsia, EarlyView.
Abstract Valproic acid (VPA) is a first‐line antiseizure medication (ASM) that is highly efficacious for treating generalized and focal epilepsy disorders. Unfortunately, due to its strong association with teratogenic effects culminating in fetal valproate spectrum disorder (FVSD), which may include neurocognitive and neurobehavioral deficits, the drug
Daniel Sandvik, Elena Vianca, Alison Anderson, Muhammad Shahid Javaid, Terence J. O'Brien, Ana Antonic‐Baker   +5 more
wiley   +1 more source

kcnb1 loss of function in zebrafish causes neurodevelopmental and epileptic disorders associated with γ‐aminobutyric acid dysregulation

Epilepsia, EarlyView.
Abstract Objective KCNB1 encodes an α‐subunit of the delayed‐rectifier voltage‐dependent potassium channel Kv2.1. De novo pathogenic variants of KCNB1 have been linked to developmental and epileptic encephalopathies (DEEs), diagnosed in early childhood and sharing limited treatment options.
Lauralee Robichon, Claire Bar, Anca Marian, Lisa Lehmann, Solène Renault, Edor Kabashi, Sorana Ciura, Rima Nabbout   +7 more
wiley   +1 more source

d‐amino acids: new functional insights

The FEBS Journal, EarlyView.
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni, Natasa Kustrimovic, Luciano Piubelli, Elena Rosini, Valentina Rabattoni, Silvia Sacchi   +5 more
wiley   +1 more source

Neurotrophin-6 is a new member of the nerve growth factor family [PDF]

, 1994
Rudolf Götz, Reinhard W. Köster, Christoph Winkler, Friedrich Raulf, Friedrich Lottspeich, Manfred Schartl, H. Thoenen   +6 more
openalex   +1 more source

Exploring the roles of conserved context‐dependent cis‐regulatory elements (cdCREs) in multicellularity, human health and disease

The FEBS Journal, EarlyView.
Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan, Alexander Rattray, Greg Hutchings, Elizabeth Hay, Chris Murgatroyd, Alasdair MacKenzie   +5 more
wiley   +1 more source