Results 11 to 20 of about 47,357 (330)

The role of the TrkB-T1 receptor in the neurotrophin-4/5 antagonism of brain-derived neurotrophic factor on corticostriatal synaptic transmission

open access: yesNeural Regeneration Research, 2020
This manuscript reviews the function and fundamental characteristics of the neurotrophins and their receptors to introduce the reader to the differential effects exhibited by the neurotrophins; brain-derived neurotrophic factor and neurotrophin 4/5 when ...
Elizabeth Hernandez-Echeagaray
doaj   +1 more source

Recent Advances in the Molecular and Cellular Mechanisms of gp120-Mediated Neurotoxicity

open access: yesCells, 2022
Axonal degeneration and loss of synapses are often seen in different brain areas of people living with human immunodeficiency virus (HIV). Nevertheless, the underlying causes of the pathological alterations observed in these individuals are poorly ...
Valeria Avdoshina, Italo Mocchetti
doaj   +1 more source

TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death [PDF]

open access: yes, 1997
Newborn mice carrying targeted mutations in genes encoding neurotrophins or their signaling Trk receptors display severe neuronal deficits in the peripheral nervous system but not in the CNS. In this study, we show that trkB (¿/¿) mice have a significant
Alcántara Horrillo, Soledad   +5 more
core   +1 more source

Neurotrophins as Therapeutic Agents for Parkinson’s Disease; New Chances From Focused Ultrasound?

open access: yesFrontiers in Neuroscience, 2022
Magnetic Resonance–guided Focused Ultrasound (MRgFUS) represents an effective micro-lesioning approach to target pharmaco-resistant tremor, mostly in patients afflicted by essential tremor (ET) and/or Parkinson’s disease (PD).
Alessandro Stefani   +9 more
doaj   +1 more source

Drosophila Neurotrophins Reveal a Common Mechanism for Nervous System Formation [PDF]

open access: yes, 2008
Neurotrophic interactions occur in Drosophila, but to date, no neurotrophic factor had been found. Neurotrophins are the main vertebrate secreted signalling molecules that link nervous system structure and function: they regulate neuronal survival ...
Aberle   +136 more
core   +4 more sources

Neurotrophins

open access: yesKocatepe Veterinary Journal, 2014
Nörotrofinler, nöronların sağkalımını ve fonksiyonlarını etkileyen, sinaptik fonksiyonu ve sinaptik plastisiteyi kontrol eden polipeptid yapılı büyüme faktör ailesidir. Nörotrofin ailesi üyeleri, sinir büyüme faktörü, beyin kaynaklı nörotrofik faktör, nörotrofin-3, nörotrofin-4/5, nörotrofin-6, ve nörotrofin7’dir.
KAZAK, Filiz, YARIM, Gül Fatma
openaire   +4 more sources

Recent advances in understanding neurotrophin signaling [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
The nerve growth factor family of growth factors, collectively known as neurotrophins, are evolutionarily ancient regulators with an enormous range of biological functions.
Mark Bothwell
doaj   +1 more source

Cellular and molecular mechanisms of perineural invasion of pancreatic ductal adenocarcinoma

open access: yesCancer Communications, 2021
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignant disease with a unique tumor microenvironment surrounded by an interlaced network of cancer and noncancerous cells.
Jingbo Li, Rui Kang, Daolin Tang
doaj   +1 more source

The self-organization of combinatoriality and phonotactics in vocalization systems [PDF]

open access: yes, 2005
This paper shows how a society of agents can self-organize a shared vocalization system that is discrete, combinatorial and has a form of primitive phonotactics, starting from holistic inarticulate vocalizations. The originality of the system is that: (1)
Oudeyer, Dr. P-Y.
core   +1 more source

Angiogenesis in Gynecological Cancers: Role of Neurotrophins

open access: yesFrontiers in Oncology, 2019
Angiogenesis, or generation of new blood vessels from other pre-existing, is a key process to maintain the supply of nutrients and oxygen in tissues. Unfortunately, this process is exacerbated in pathologies such as retinopathies and cancers with high ...
Maritza P. Garrido   +6 more
doaj   +1 more source

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