Plasma brain-derived neurotrophic factor before hemodialysis reduces the risk of depression in patients with chronic renal failure [PDF]
Renal FailureBackground Neurotrophins are related with depressive disorders. Significant neurotrophins variations occur during renal replacement therapy, but whether peri-hemodialysis availability is associated with depression in patients with Chronic Kidney Disease (
Juan Antonio Suárez-Cuenca +13 more
doaj +2 more sources
The Neurotrophin System in the Postnatal Brain—An Introduction [PDF]
BiologyNeurotrophins can bind to and signal through specific receptors that belong to the class of the Trk family of tyrosine protein kinase receptors. In addition, they can bind and signal through a low-affinity receptor, termed p75NTR.
Oliver von Bohlen und Halbach +1 more
doaj +2 more sources
Axonal Regeneration after Spinal Cord Injury: Molecular Mechanisms, Regulatory Pathways, and Novel Strategies [PDF]
BiologyAxonal regeneration in the spinal cord after traumatic injuries presents a challenge for researchers, primarily due to the nature of adult neurons and the inhibitory environment that obstructs neuronal regrowth.
Mohammed Ibrahim Elmalky +3 more
doaj +2 more sources
BDNF Differentially Affects Low- and High-Frequency Neurons in a Primary Nucleus of the Chicken Auditory Brainstem [PDF]
BiologyNeurotrophins are proteins that mediate neuronal development using spatiotemporal signaling gradients. The chicken nucleus magnocellularis (NM), an analogous structure to the mammalian anteroventral cochlear nucleus, provides a model system in which ...
Kristine McLellan +5 more
doaj +2 more sources
Muscle Progenitors Derived from Extraocular Muscles Express Higher Levels of Neurotrophins and their Receptors than other Cranial and Limb Muscles [PDF]
, 2020 Extraocular muscles (EOMs) show resistance to muscle dystrophies and sarcopenia. It has been recently demonstrated that they are endowed with different types of myogenic cells, all of which present an outstanding regenerative potential. Neurotrophins are
Benítez Temiño, Beatriz +3 more
core +1 more source
Structure and evolution of neuronal wiring receptors and ligands
Developmental Dynamics, Volume 252, Issue 1, Page 27-60, January 2023., 2023 Abstract One of the fundamental properties of a neuronal circuit is the map of its connections. The cellular and developmental processes that allow for the growth of axons and dendrites, selection of synaptic targets, and formation of functional synapses use neuronal surface receptors and their interactions with other surface receptors, secreted ...
Elena Cortés +2 more
wiley +1 more source
Neurotrophin-induced migration and neuronal differentiation of multipotent astrocytic stem cells in vitro. [PDF]
PLoS ONE, 2012 Hypoxic ischemic encephalopathy (HIE) affects 2-3 per 1000 full-term neonates. Up to 75% of newborns with severe HIE die or have severe neurological handicaps.
Martha Douglas-Escobar +4 more
doaj +1 more source
Polycistronic Delivery of IL-10 and NT-3 Promotes Oligodendrocyte Myelination and Functional Recovery in a Mouse Spinal Cord Injury Model. [PDF]
, 2020 One million estimated cases of spinal cord injury (SCI) have been reported in the United States and repairing an injury has constituted a difficult clinical challenge.
Anderson, Aileen J +8 more
core +1 more source
Wiring the senses: Factors that regulate peripheral axon pathfinding in sensory systems
Developmental Dynamics, Volume 252, Issue 1, Page 81-103, January 2023., 2023 Abstract Sensory neurons of the head are the ones that transmit the information about the external world to our brain for its processing. Axons from cranial sensory neurons sense different chemoattractant and chemorepulsive molecules during the journey and in the target tissue to establish the precise innervation with brain neurons and/or receptor ...
Gemma Nomdedeu‐Sancho, Berta Alsina
wiley +1 more source
Neuron, 2002 The family of neurotrophic factors known as neurotrophins has yielded a series of surprises, both with regard to the broad extent of their functional roles and the remarkable complexity of their signaling mechanisms. The recent discovery that a neurotrophin precursor protein and its proteolytically processed products may differentially activate pro ...
Moses V. Chao, Mark Bothwell
openaire +3 more sources