Results 51 to 60 of about 44,486 (289)
p75 neurotrophin receptor regulates energy balance in obesity [PDF]
, 2016 Obesity and metabolic syndrome reflect the dysregulation of molecular pathways that control energy homeostasis. Here, we show that the p75 neurotrophin receptor (p75NTR) controls energy expenditure in obese mice on a high-fat diet (HFD).
Akassoglou, Katerina +16 more
core +3 more sources
International Archives of Otorhinolaryngology, 2023 Introduction The nonspecific hyperreactivity of rhinitis has been attributed to neurotrophins activating sensory nerves and inflammatory cells.
Thiago Carvalho +6 more
doaj +1 more source
Training-induced gene expression plasticity in cardiac function and neural regulation for ultra-trail runners [PDF]
, 2015 This study aims to assess the gene regulatory response from a group of 16 athletes and to observe the plasticity induced by their training regime on the gene expression response after their participation in an 82km race.
Brotons, Daniel +4 more
core +1 more source
Mice with altered BDNF signaling as models for mood disorders and antidepressant effects
Frontiers in Behavioral Neuroscience, 2014 Brain-derived neurotrophic factor (BDNF) and its receptor tyrosine kinase TrkB support neuronal survival during development and promote connectivity and plasticity in the adult brain.
Jesse Saku Olavi Lindholm +1 more
doaj +1 more source
Annals of Indian Academy of Neurology, 2020 Objective: Despite advances made in the treatment of ischemic stroke, it still remains one of the leading causes of mortality and disability worldwide.
Adina Hutanu +4 more
doaj +1 more source
Biomedicines, 2022 Alzheimer’s disease (AD) is a neurodegenerative disorder, comprising 70% of dementia diagnoses worldwide and affecting 1 in 9 people over the age of 65.
Grace Cunliffe +3 more
doaj +1 more source
A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury. [PDF]
, 2016 The p75 neurotrophin receptor is important in multiple physiological actions including neuronal survival and neurite outgrowth during development, and after central nervous system injury.
Alam, Antoine +20 more
core +1 more source
Neurotrophin Signaling in Medulloblastoma [PDF]
Cancers, 2020 Neurotrophins are a family of secreted proteins that act by binding to tropomyosin receptor kinase (Trk) or p75NTR receptors to regulate nervous system development and plasticity. Increasing evidence indicates that neurotrophins and their receptors in cancer cells play a role in tumor growth and resistance to treatment.
Amanda Thomaz +9 more
openaire +3 more sources
Nerve Growth Factor and Autoimmune Diseases
Current Issues in Molecular Biology, 2023 NGF plays a crucial immunomodulatory role and increased levels are found in numerous tissues during autoimmune states. NGF directly modulates innate and adaptive immune responses of B and T cells and causes the release of neuropeptides and ...
Sergio Terracina +10 more
doaj +1 more source
p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks. [PDF]
, 2013 The p75 neurotrophin receptor (p75(NTR)) is a member of the tumor necrosis factor receptor superfamily with a widespread pattern of expression in tissues such as the brain, liver, lung, and muscle.
Akassoglou, Katerina +7 more
core +2 more sources