Results 131 to 140 of about 8,477 (148)

Regulation and function of neutral sphingomyelinase 2

2023
Samia Mohammed, Jihui Ren, Botheina Ghandour, Christopher J. Clarke, Yusuf A. Hannun   +4 more
openaire   +1 more source

Neutral Sphingomyelinase-2 Restrains TAZ to Suppress Breast Tumor Growth

ABSTRACT Loss of tumor suppressor gene (TSG) activity is pervasive across cancers and linked to worse clinical outcomes, yet therapeutic efforts aimed at restoring TSGs have remained elusive. One underexplored avenue to address this problem is the targeting of metabolic signaling pathways that actively enforce tumor suppressive programs.
Andrew E. Resnick, Victoria Franzi, Botheina K. Ghandour, Sam B. Chiappone, Sebastien Lalanne, Monica E. Alexander, Deanna M. Peperno, Jowana Obeid, Ishmam Pritam, Ian D. Miranda, Nicolas Coant, Michael V. Airola, Mehdi Damaghi, Fabiola N. Velazquez, Yusuf A. Hannun, Christopher J. Clarke   +15 more
openaire   +1 more source

Acid and Neutral Sphingomyelinase Behavior in Radiation-Induced Liver Pyroptosis and in the Protective/Preventive Role of rMnSOD

International Journal of Molecular Sciences, 2020
Francesco Saverio Ambesi Impiombato, Carmela Conte, Irina Nakashidze   +2 more
exaly  

Effect of 1α,25(OH)2 Vitamin D3 in Mutant P53 Glioblastoma Cells: Involvement of Neutral Sphingomyelinase1

Cancers, 2020
Carmela Conte, Irina Nakashidze, Tommaso Beccari   +2 more
exaly  

Neutral sphingomyelinase: Localization in rat liver nuclei and involvement in regeneration/proliferation

Molecular and Cellular Biochemistry, 1995
Chatterjee Subroto
exaly  

SMALL MOLECULE NEUTRAL SPHINGOMYELINASE 2 (nSMase2) INHIBITORS

2020
TSUKAMOTO TAKASHI, HIN NIYADA, STEPANEK ONDREJ, SLUSHER BARABRA, ROJAS CAMILO, THOMAS AJIT G   +5 more
openaire   +3 more sources

Factor Associated With Neutral Sphingomyelinase Activation and Its Role in Cardiac Cell Death

Circulation Research, 2003
Chris Glembotski, Mei Guo, Roger A Sabbadini   +2 more
exaly  

Holotoxin A1 Induces Apoptosis by Activating Acid Sphingomyelinase and Neutral Sphingomyelinase in K562 and Human Primary Leukemia Cells

Marine Drugs, 2018
Joo-In Park, Valentin Stonik, Jin-Yeong Han   +2 more
exaly  

Exosomes mediate Zika virus transmission through SMPD3 neutral Sphingomyelinase in cortical neurons

Emerging Microbes and Infections, 2019
Girish Neelakanta, Wenshuo Zhou, Michael Sherman   +2 more
exaly  

Neutral Sphingomyelinase 2 Is an Important Mediator of Cellular Stress Responses

Forum on Immunopathological Diseases and Therapeutics, 2012
Bei Lei Sun, Bulent Mutus
openaire   +1 more source