Results 111 to 120 of about 8,477 (148)

Neutral sphingomyelinase 2 inhibitors based on the 4-(1H-imidazol-2-yl)-2,6-dialkoxyphenol scaffold. [PDF]

Eur J Med Chem, 2019
Stepanek O, Hin N, Thomas AG, Dash RP, Alt J, Rais R, Rojas C, Slusher BS, Tsukamoto T.   +8 more
europepmc   +1 more source

Expression of Concern: Stress-Induced Sphingolipid Signaling: Role of Type-2 Neutral Sphingomyelinase in Murine Cell Apoptosis and Proliferation.

PLoS ONE, 2018
PLOS ONE Editors
doaj   +1 more source

Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869. [PDF]

Cell Discov, 2018
Huang Y, Li Y, Zhang H, Zhao R, Jing R, Xu Y, He M, Peer J, Kim YC, Luo J, Tong Z, Zheng J.   +11 more
europepmc   +1 more source

Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide. [PDF]

Cell Death Dis, 2018
Back MJ, Ha HC, Fu Z, Choi JM, Piao Y, Won JH, Jang JM, Shin IC, Kim DK.   +8 more
europepmc   +1 more source

Enriched Expression of Neutral Sphingomyelinase 2 in the Striatum is Essential for Regulation of Lipid Raft Content and Motor Coordination. [PDF]

Mol Neurobiol, 2018
Tan LH, Tan AJ, Ng YY, Chua JJ, Chew WS, Muralidharan S, Torta F, Dutta B, Sze SK, Herr DR, Ong WY.   +10 more
europepmc   +1 more source

DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation. [PDF]

Sci Rep, 2018
Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer M, Slusher BS.   +17 more
europepmc   +1 more source

Neutral Sphingomyelinase-2 Deficiency Ameliorates Alzheimer's Disease Pathology and Improves Cognition in the 5XFAD Mouse. [PDF]

J Neurosci, 2016
Dinkins MB, Enasko J, Hernandez C, Wang G, Kong J, Helwa I, Liu Y, Terry AV, Bieberich E.   +8 more
europepmc   +1 more source

P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest. [PDF]

Cell Death Dis, 2015
Shamseddine AA, Clarke CJ, Carroll B, Airola MV, Mohammed S, Rella A, Obeid LM, Hannun YA.   +7 more
europepmc   +1 more source

RETRACTED: Cataldi et al. Neutral Sphingomyelinase Modulation in the Protective/Preventive Role of rMnSOD from Radiation-Induced Damage in the Brain. <i>Int. J. Mol. Sci.</i> 2019, <i>20</i>, 5431. [PDF]

Int J Mol Sci
Cataldi S, Borrelli A, Ceccarini MR, Nakashidze I, Codini M, Belov O, Ivanov A, Krasavin E, Ferri I, Conte C, Patria FF, Traina G, Beccari T, Mancini A, Curcio F, Ambesi-Impiombato FS, Albi E.   +16 more
europepmc   +1 more source

Exploring ceramide as a novel biomarker and therapeutic target for Alzheimer's disease. [PDF]

Front Neurosci
Zhao W, Liu X, Yao Y, Yu Y, Hu Z.
europepmc   +1 more source