Results 41 to 50 of about 448,029 (330)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Current Status and Prospects of Resource Recycling Technology for Fiber-Reinforced Polymers in the New Energy Industry

open access: yes能源环境保护
Fiber-reinforced polymers (FRPs), composed of reinforcing fibers and resin matrices, exhibit outstanding characteristics such as low density, high strength, corrosion resistance, and superior mechanical performance.
Long JIAO   +7 more
doaj   +1 more source

Stimulus-Responsive Afterglow Carbon Dots from Internal Mechanism to Potential Application

open access: yesNanomaterials
Stimulus-responsive afterglow materials refer to a class of substances whose afterglow characteristics alter under external stimuli, showing considerable potential for advanced applications in anti-counterfeiting, optoelectronic displays, chemical ...
Chongye Xia   +5 more
doaj   +1 more source

On Neutralization of Charged Black Holes

open access: yes, 2019
For non-spinning, charged (Reissner–Nordström) black holes, the particles with an opposite sign of charge with respect to that of the black hole will be pulled into the black hole by the extra electromagnetic force.
Cao, Zhoujian   +3 more
core   +2 more sources

State Neutrality [PDF]

open access: yes, 2012
This article attempts to spell out the main tenets of the principle of state neutrality and to explain how they hang together. It examines the central objections, and explores revisions that may enhance the theory's defensibility. Specifically, it discusses neutrality as non-discrimination, neutrality as shared reasons, objections to liberal neutrality,
openaire   +2 more sources

Neutral syndrome

open access: yesNature Human Behaviour, 2020
Neutral models of evolution assume the absence of natural selection. Formerly confined to ecology and evolutionary biology, neutral models are spreading. In recent years they've been applied to explaining the diversity of baby names, scientific citations, cryptocurrencies, pot decorations, literary lexica, tumour variants and much more besides.
Armand M. Leroi   +4 more
openaire   +4 more sources

Ultracold neutral plasmas [PDF]

open access: yesAIP Conference Proceedings, 2002
Ultracold neutral plasmas occupy an exotic regime of plasma physics in which electrons form a swarming, neutralizing background for ions that sluggishly move in a correlated manner. Strong interactions between the charged particles give rise to surprising dynamics such as oscillations of the average kinetic energy during equilibration and extremely ...
Killian, T. C.   +3 more
openaire   +4 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Accelerated Development of Vapor Deposition Technology for Efficient Perovskite Solar Cells via Accurate and Practical Machine Learning Tools

open access: yesAdvanced Science
The development of vapor deposition technology will accelerate the process of perovskite solar cells (PSCs) moving from laboratory scale to industrialization. However, the multi‐dimensional and complex parameter space will inevitably increase the cost of
Long Luo   +8 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

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