Results 11 to 20 of about 776,059 (341)

Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress [PDF]

, 2012
Acknowledgments We thank Alexander Johnson (yhb1D/D), Karl Kuchler (sodD/D mutants), Janet Quinn (hog1D/D, hog1/cap1D/D, trx1D/D) and Peter Staib (ssu1D/D) for providing mutant strains.
A Cederlund, A da Silva Dantas, Alistair J. P. Brown, B Amulic, B Enjalbert, B Enjalbert, B Hube, B Hube, BD Ullmann, Bernhard Hube, BH Youseff, BS Hromatka, C Fradin, Christine Dunker, CJ Barelle, CJ Barelle, CJ Heilmann, D Wilson, DA Smith, DL Moyes, DL Moyes, DM Arana, DR Wysong, FC Fang, GM Chaves, Hanna Windecker, I Rubin-Bejerano, I Wozniok, ID Jacobsen, IE Frohner, Iryna M. Bohovych, J Cheetham, M de Jesus-Berrios, M Martchenko, MA Wheeler, MC Lorenz, MC Lorenz, MG Netea, Oliver Kurzai, Oscar Zaragoza, P Nordenfelt, Pedro Miramón, R Alonso-Monge, R Pathania, RA Calderone, RI Lehrer, SC Cheng, TM Stevanin, TM Stevanin, V Brinkmann, W Bellamy, W Chiranand   +51 more
core   +9 more sources

Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing [PDF]

, 2007
Airway infection by the Gram-positive pathogen Streptococcus pneumoniae (Sp) leads to recruitment of neutrophils but limited bacterial killing by these cells.
Clarke, Thomas B., Dowson, Christopher G., Lysenko, Elena S., Ratner, Adam J., Roper, David I., Shchepetov, Mikhail, Weiser, Jeffrey N.   +6 more
core   +7 more sources

Skap2 is required for β2 integrin-mediated neutrophil recruitment and functions. [PDF]

, 2017
Integrin activation is required for neutrophil functions. Impaired integrin activation on neutrophils is the hallmark of leukocyte adhesion deficiency (LAD) syndrome in humans, characterized by impaired leukocyte recruitment and recurrent infections. The
Bardel, Bernadette, Block, Helena, Bokemeyer, Arne, Boras, Mark, Heitplatz, Barbara, Kliche, Stefanie, Lowell, Clifford, Reinhold, Annegret, Rossaint, Jan, Van Marck, Veerle, Volmering, Stephanie, Zarbock, Alexander   +11 more
core   +2 more sources

Crucial role of local peroxynitrite formation in neutrophil-induced endothelial cell activation [PDF]

, 2003
Introduction and methods: The reaction of superoxide anions and NO not only results in a decreased availability of NO, but also leads to the formation of peroxynitrite, the role of which in the cardiovascular system is still discussed controversially. In
Gloe, Torsten, Keller, Matthias, Klauss, Volker, Krötz, Florian, Pohl, Ulrich, Schiele, Thomas M., Sohn, Hae-Young, Theisen, Karl, Zahler, Stefan   +8 more
core   +1 more source

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo [PDF]

, 2013
Neutrophil recruitment from blood to extravascular sites of sterile or infectious tissue damage is a hallmark of early innate immune responses, and the molecular events leading to cell exit from the bloodstream have been well defined1,2. Once outside the
Afonso, P., Angermann, B., Germain, R., Kastenmüller, W., Lämmermann, T., Parent, C., Wang, J.   +6 more
core   +2 more sources

Hemodialysis membrane-related neutrophil dysfunctions and pentoxifylline - a pilot study [PDF]

, 1990
Hemodialysis treatment is associated with activation of neutrophil granulocytes. Pentoxifylline has been shown to inhibit neutrophil activation in vitro and in vivo.
Hoffmann, H., Jochum, Marianne, Schiffl, H., Spannagl, Michael   +3 more
core   +1 more source

Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung [PDF]

, 2013
Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome,
A Cross, A G Rossi, A Planaguma, AE Leitch, AE Leitch, AG Rossi, AL Alessandri, B Dibbert, BM Fournier, C Akgul, C D Lucas, C Haslett, C Nathan, C T Robb, CD Lucas, CN Serhan, D A Dorward, DA Dorward, DA Moulding, DA Moulding, DA Steimer, DJ Wardle, E Abraham, EE McGrath, GL Bannenberg, GS Worthen, H Liu, HG Folkesson, HM Marriott, I Dzhagalov St, I Nicoletti, J A Marwick, J Liang, JS Savill, K C Allen, K Ganeshan, KP Steinberg, L Fialkow, L Santo, M A Tait, MA Matthay, N Chiang, N Fotouhi-Ardakani, N Hirani, O Eickmeier, R Boxio, R Duffin, S Brode, S Fox, S Fox, S Michlewska, SJ Leuenroth, SL Poe, SP Garrison, T Hideshima, T Tanaka, TR Ulich, U Koedel, Y Liu   +58 more
core   +1 more source

Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung [PDF]

, 2014
Siglec-E is a sialic acid-binding Ig-like lectin expressed on murine myeloid cells. It has recently been shown to function as a negative regulator of β2-integrin-dependent neutrophil recruitment to the lung following exposure to lipopolysaccharide (LPS).
Anderson, Boyle, Boyle, Chen, Chen, Doerschuk, Fisher, Franke, Gao, Grommes, Hoyal, Kielland, Kulkarni, Liu, Matthay, McMillan, Mócsai, Pollock, Segal, Segal, Segal, Zhang, Zhang, Zhang   +23 more
core   +3 more sources

Regulation of neutrophil senescence by microRNAs [PDF]

, 2011
Neutrophils are rapidly recruited to sites of tissue injury or infection, where they protect against invading pathogens. Neutrophil functions are limited by a process of neutrophil senescence, which renders the cells unable to respond to chemoattractants,
A Bonauer, A Lee, AD Kennedy, AS Cowburn, AW Ford-Hutchinson, C Haslett, C Martin, CH Wang, CL Andersen, DP Bartel, E Berezikov, E Tsitsiou, EP Cronkite, F Bazzoni, F Colotta, F Fazi, Frank R. DeLeo, GM Bokoch, H Su, H Xia, I Sabroe, I Sabroe, J Davidson-Moncada, J Savill, J Yu, James W. Catto, JB Johnnidis, JJ Lum, JL Mott, Jon R. Ward, JR Ward, LR Prince, M Merkerova, M Scherr, Marta Milo, MK Whyte, MK Whyte, Moira K. B. Whyte, OD Weiner, P Scapini, PA Davoren, Paul R. Heath, PT Nelson, R Chhabra, R Yi, RE Stringer, RW Watson, S Huang, S Radom-Aizik, S Slezak, SA Renshaw, SD Kobayashi, SD Kobayashi, Stephen A. Renshaw, W Filipowicz, W Huang da, WC Liles, WP Tsang, Y Lee, Y Wang, YZ Pan   +60 more
core   +5 more sources

Myeloid Poldip2 Contributes to the Development of Pulmonary Inflammation by Regulating Neutrophil Adhesion in a Murine Model of Acute Respiratory Distress Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Lung injury, a severe adverse outcome of lipopolysaccharide‐induced acute respiratory distress syndrome, is attributed to excessive neutrophil recruitment and effector response.
Ziwei Ou, Elena Dolmatova, Rohan Mandavilli, Hongyan Qu, Georgette Gafford, Taylor White, Alejandra Valdivia, Bernard Lassègue, Marina S. Hernandes, Kathy K. Griendling   +9 more
doaj   +1 more source