Results 11 to 20 of about 1,017,928 (387)
Immunity, 2021 Neutrophils are immune cells with unusual biological features that furnish potent antimicrobial properties. These cells phagocytose and subsequently kill prokaryotic and eukaryotic organisms very efficiently. Importantly, it is not only their ability to attack microbes within a constrained intracellular compartment that endows neutrophils with ...
G. Burn +4 more
semanticscholar +3 more sources
Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19 [PDF]
SSRN Electronic Journal, 2020 Background: Cases of excessive neutrophil counts in the blood in severe coronavirus disease (COVID-19) patients have drawn significant attention. Neutrophil infiltration was also noted on the pathological findings from autopsies.
Jun Wang +9 more
semanticscholar +8 more sources
Frontiers in Immunology, 2017 Neutrophils are the most abundant white blood cells and are the first recruited to inflammatory sites. Neutrophils are an important component of the tumor stroma and can exert both anti-tumoral and pro-tumoral activities, depending on their maturation and activation state.
Matteo Massara +12 more
openaire +5 more sources
La Revue de Médecine Interne, 2022 Neutrophilic dermatoses (ND) are a group of inflammatory skin conditions characterized by a neutrophilic infiltrate on histopathology with no evidence of infection. ND are classified based upon the localization of neutrophils within the skin and clinical features.
Delaleu, Jeremie +15 more
openaire +2 more sources
Gut microbes, 2021 Host-microbial cross-talk plays a crucial role in maintenance of gut homeostasis. However, how microbiota-derived metabolites, e.g., butyrate, regulate functions of neutrophils in the pathogenesis of inflammatory bowel disease (IBD) remains elusive.
Gengfeng Li +9 more
semanticscholar +1 more source
Targeting potential drivers of COVID-19: Neutrophil extracellular traps
Journal of Experimental Medicine, 2020 In this Perspective, autopsy results and literature are presented supporting the hypothesis that neutrophil extracellular traps (NETs) may contribute to organ damage and mortality in COVID-19.
B. Barnes +22 more
semanticscholar +1 more source
Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress [PDF]
, 2012 Acknowledgments We thank Alexander Johnson (yhb1D/D), Karl Kuchler (sodD/D mutants), Janet Quinn (hog1D/D, hog1/cap1D/D, trx1D/D) and Peter Staib (ssu1D/D) for providing mutant strains.
A Cederlund +51 more
core +10 more sources
Neutrophil extracellular traps in COVID-19.
JCI Insight, 2020 In severe cases of coronavirus disease 2019 (COVID-19), viral pneumonia progresses to respiratory failure. Neutrophil extracellular traps (NETs) are extracellular webs of chromatin, microbicidal proteins, and oxidant enzymes that are released by ...
Y. Zuo +12 more
semanticscholar +1 more source
Frontiers in Immunology, 2019 Leprosy is an infectious disease caused by the intracellular bacillus Mycobacterium leprae that mainly affects the skin and peripheral nerves. One of the most intriguing aspects of leprosy is the diversity of its clinical forms. Paucibacillary patients are characterized as having less than five skin lesions and rare bacilli while the lesions in ...
Jessica Brandão dos Santos +7 more
openaire +4 more sources
Autophagy in neutrophils [PDF]
The Korean Journal of Physiology & Pharmacology, 2020 Autophagy is a highly conserved intracellular degradation and energy-recycling mechanism that contributes to the maintenance of cellular homeostasis. Extensive researches over the past decades have defined the role of autophagy innate immune cells. In this review, we describe the current state of knowledge regarding the role of autophagy in neutrophil ...
Chang-Won Hong +2 more
openaire +3 more sources