Results 101 to 110 of about 57,341 (275)

Nanoemulsions for Skin Delivery of Essential Oils: A Systematic Review

Phytotherapy Research, EarlyView.
ABSTRACT Essential oils (EOs) are recognized for their multiple health benefits. However, their high volatility, low stability, and limited water solubility limit their effective application. This systematic review aims to assess the use of nanoemulsions as delivery systems for the topical administration of EOs, highlighting their efficacy, safety, and
Thais Leticia Moreira da Silva, Anna Claudia Morais de Oliveira Capote, Flávio Luís Beltrame, Priscileila Colerato Ferrari   +3 more
wiley   +1 more source

Usefulness of estimation of cord blood lipopolysaccharide binding protein and neutrophilic elastase concentration versus C-reactive protein concentration in the prediction of early-onset neonatal infections

Journal of Education, Health and Sport
            Introduction. Congenital infection in a newborn is an infection caused by pathogens passed on to the child by the mother intrauterine or perinatally. Sepsis is the most common form of early-onset infection in newborns.
Agnieszka Kordek, Anna Błażejczak, Justyna Kordek   +2 more
doaj   +1 more source

Emerging pharmacological treatments to prevent abdominal aortic aneurysm growth and rupture [PDF]

, 2015
Abdominal aortic aneurysm (AAA) is a local expansion of the abdominal aorta wall caused by a complex multifactorial maladaptive vascular remodeling. Despite recent advances in the management of cardiovascular diseases, there currently is no established ...
Fraga-Silva, Rodrigo, Stergiopulos, Nikolaos, Trachet, Bram   +2 more
core   +2 more sources

PEARL: Protein Eluting Alginate with Recombinant Lactobacilli

Small, EarlyView.
Probiotic lactobacilli meet engineered living materials: This study introduces PEARL (protein eluting alginate with recombinant lactobacilli), an innovative engineered living material combining Lactiplantibacillus plantarum and alginate beads for controlled protein release.
Varun Sai Tadimarri, Marc Blanch‐Asensio, Ketaki Deshpande, Jonas Baumann, Carole Baumann, Rolf Müller, Sara Trujillo, Shrikrishnan Sankaran   +7 more
wiley   +1 more source

Biomedical Significance of Alpha1-Antitrypsin: An Overview

Journal of Clinical and Biomedical Sciences, 2016
Alpha1-antitrypsin (α1-AT) is a natural, endogenous inhibitor of serine proteases with preferential activity towards neutrophil elastase (NE), the enzyme that possess the ability to cleave important connective tissue protein, elastin. The normal
Mamatha Kunder, A V M Kutty
doaj   +1 more source

Mechanism elucidation of cell‐selective fluorescent probes

Smart Molecules, EarlyView.
This perspective outlines five mechanistic strategies—Protein‐oriented, carbohydrate‐oriented, lipid‐oriented, gating‐oriented, and metabolism‐oriented live‐cell distinctions—for achieving cell‐selective fluorescence in live‐cell imaging. By classifying probes based on their interactions with proteins, carbohydrates, lipids, transporters, or metabolic ...
Sourav Sarkar, Young‐Tae Chang
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source

Excessive Neutrophil Activity in Gestational Diabetes Mellitus: Could It Contribute to the Development of Preeclampsia?

Frontiers in Endocrinology, 2018
Gestational diabetes mellitus is a transient form of glucose intolerance occurring during pregnancy. Pregnancies affected by gestational diabetes mellitus are at risk for the development of preeclampsia, a severe life threatening condition, associated ...
Lenka Vokalova, Lenka Vokalova, Shane V. van Breda, Shane V. van Breda, Xi Lun Ye, Evelyn A. Huhn, Nandor G. Than, Paul Hasler, Olav Lapaire, Irene Hoesli, Simona W. Rossi, Sinuhe Hahn   +11 more
doaj   +1 more source

Endotracheal tube-induced sore throat pain and inflammation is coupled to the release of mitochondrial DNA [PDF]

, 2017
In the absence of infection, the pathophysiology of endotracheal tube-induced sore throat pain is unclear. Activated neutrophils release elastase, reactive oxygen species, and inflammatory cytokines known to contribute to neuropathic pain. Sterile tissue
Earhart, Alexander, Gelman, Andrew E, Ibrahim, Mohsen, Karanikolas, Menelaos, Kollef, Marin H, Kreisel, Daniel, Krupnick, Alexander S, Peruzzi, Daniela, Puyo, Carlos A, Roller, Evan   +9 more
core   +2 more sources

Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model

Allergy, EarlyView.
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang, Jing Liu, Jing Ye, Li‐Ying Sun, Hsiao Hui Ong, Yang Peng, Bing‐Qi Lin, Jun‐Hao Tu, Ke‐Shuang Wang, Yi‐Shan Xiong, Qing Luo, Mark Thong, Yu Xu, De‐Yun Wang   +13 more
wiley   +1 more source