Results 181 to 190 of about 57,341 (275)

Identification of an exosite at the neutrophil elastase/alpha-1-antitrypsin interface. [PDF]

FEBS J
Gangemi R, Bignotti M, Denardo A, Pearce CN, Ronzoni R, Lomas DA, Irving JA, Fra A, Gangemi F.   +8 more
europepmc   +1 more source

Pathomechanismus in Septic Shock [PDF]

, 1986
Duswald, Karl-Heimo, Eitel, F., Fritz, Hans, Inthorn, D., Jochum, Marianne, Schweiberer, L.   +5 more
core  

Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory

Immunology, Volume 177, Issue 2, Page 254-269, February 2026.
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco, Itziar Martín‐Ruiz, Sarai Araujo‐Aris, Diego Barriales, Janire Castelo, Leire Egia‐Mendikute, Monika Gonzalez, Jose Ezequiel Martin, Elena Molina, Maitane Mugica, Ainhoa Palacios, Iratxe Seoane, Naiara Gutiez, Estibaliz Atondo, Eneko Santos Fernández, Maddi Oyanguren, Borja Jimenez‐Lasheras, Ainize Peña‐Cearra, Ana M. Aransay, Asis Palazon, Aize Pellón, Leticia Abecia, Hector Rodriguez, Natalia Elguezabal, Juan Anguita   +24 more
wiley   +1 more source

Exosomes in Hypertrophic Scars and Keloids: Mechanisms and Therapeutic Potentials—A Narrative Review

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Hypertrophic scars and keloids, types of pathological scars, arise from dysregulated wound healing, marked by abnormal fibroblast activation and excessive extracellular matrix (ECM) deposition. Current treatments have high recurrence rates and side effects, necessitating targeted therapies. Exosomes, extracellular vesicles mediating
Mengke Wu, Jianfeng Zhang, Na Xiong, Yixiao Ma, Lingling Yong, Huaxu Liu, Qin Guo   +6 more
wiley   +1 more source

Urine Neutrophil Elastase: A Novel Predictor of ICU Admission for Patients with COVID-19 Infection. [PDF]

J Inflamm Res
Song Y, Zeng K, Zhang LK, Zhang JN, Zhang KL, Xin Y, Wang XR, Zhou YX, Li HX, Wang CS, Yu KJ.   +10 more
europepmc   +1 more source

Neutrophil elastase activates the release of extracellular traps from COPD blood monocyte-derived macrophages. [PDF]

Clin Transl Sci, 2023
Zheng S, Kummarapurugu AB, Bulut GB, Syed A, Kang L, Voynow JA.   +5 more
europepmc   +1 more source

Neutrophil elastase activates macrophage calpain as a mechanism for phagocytic failure. [PDF]

Am J Physiol Lung Cell Mol Physiol
Ma J, Kummarapurugu AB, Zheng S, Ghio AJ, Deshpande LS, Voynow JA.   +5 more
europepmc   +1 more source

Identification and characterization of aptameric inhibitors of human neutrophil elastase. [PDF]

J Biol Chem, 2023
Malicki S, Książek M, Sochaj Gregorczyk A, Kamińska M, Golda A, Chruścicka B, Mizgalska D, Potempa J, Marti HP, Kozieł J, Wieczorek M, Pieczykolan J, Mydel P, Dubin G.   +13 more
europepmc   +1 more source

Proteinase inhibitor candidates for therapy of enzyme-inhibitor imbalances [PDF]

, 1992
Casali, L., Collins, John, Fritz, Hans, Grassi, C., Jochum, Marianne, Luisetti, M., Travis, J.   +6 more
core   +1 more source

Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice. [PDF]

Arterioscler Thromb Vasc Biol, 2023
Yang M, Zhou X, Pearce SWA, Yang Z, Chen Q, Niu K, Liu C, Luo J, Li D, Shao Y, Zhang C, Chen D, Wu Q, Cutillas PR, Zhao L, Xiao Q, Zhang L.   +16 more
europepmc   +1 more source