Results 1 to 10 of about 499,327 (290)

Neutrophils and Asthma

open access: yesDiagnostics, 2022
Although eosinophilic inflammation is characteristic of asthma pathogenesis, neutrophilic inflammation is also marked, and eosinophils and neutrophils can coexist in some cases. Based on the proportion of sputum cell differentiation, asthma is classified
Akira Yamasaki   +2 more
doaj   +3 more sources

Candida albicans-stimulated hematopoietic stem and progenitor cells generate trained neutrophils with enhanced mitochondrial ROS production that defend against infection. [PDF]

open access: yesPLoS Pathogens
Central trained immunity, induced via reprogramming of hematopoietic stem and progenitor cells (HSPCs), mediates sustained heightened responsiveness of mature myeloid cells to secondary challenges.
María Sobén   +4 more
doaj   +2 more sources

Multiple Death Pathways of Neutrophils Regulate Alveolar Macrophage Proliferation

open access: yesCells, 2022
Alveolar macrophage (AM) proliferation and self-renewal play an important role in the lung tissue microenvironment. However, the impact of immune cells, especially the neutrophils, on AM homeostasis or function is not well characterized.
Xiaochen Gao   +8 more
doaj   +1 more source

Increased Circulating of CD54highCD181low Neutrophils in Myelodysplastic Syndrome

open access: yesFrontiers in Oncology, 2021
Myelodysplastic syndromes (MDSs) are a group of heterogeneous hematopoietic stem/progenitor cells clonal diseases, characteristic features with myeloid dysplasia, leading to abnormality of neutrophils.
Liyan Yang   +8 more
doaj   +1 more source

Synovial fluid neutrophils in oligoarticular juvenile idiopathic arthritis have an altered phenotype and impaired effector functions

open access: yesArthritis Research & Therapy, 2021
Background Neutrophils are the most prevalent immune cells in the synovial fluid in inflamed joints of children with oligoarticular juvenile idiopathic arthritis (JIA).
Sabine Arve-Butler   +7 more
doaj   +1 more source

Antigen-Presenting Cell-Like Neutrophils Foster T Cell Response in Hyperlipidemic Patients and Atherosclerotic Mice

open access: yesFrontiers in Immunology, 2022
Neutrophils constitute abundant cellular components in atherosclerotic plaques. Most of the current studies are focused on the roles of granular proteins released by neutrophils in atherosclerosis.
Tingrui Zhao   +31 more
doaj   +1 more source

Neutrophils Lose the Capacity to Suppress T Cell Proliferation Upon Migration Towards Inflamed Joints in Juvenile Idiopathic Arthritis

open access: yesFrontiers in Immunology, 2022
Neutrophils are highly abundant in synovial fluid of rheumatic inflamed joints. In oligoarticular juvenile idiopathic arthritis (JIA), synovial fluid neutrophils have impaired effector functions and altered phenotype.
Sabine Arve-Butler   +12 more
doaj   +1 more source

Mesenchymal stem cells shift the pro-inflammatory phenotype of neutrophils to ameliorate acute lung injury

open access: yesStem Cell Research & Therapy, 2023
Background Mesenchymal stem cell (MSC) treatment plays a major role in the management of acute lung injury (ALI), and neutrophils are the initial line of defense against ALI.
Bing Feng   +13 more
doaj   +1 more source

Neutrophils: New Critical Regulators of Glioma

open access: yesFrontiers in Immunology, 2022
In cancer, neutrophils are an important part of the tumour microenvironment (TME). Previous studies have shown that circulating and infiltrating neutrophils are associated with malignant progression and immunosuppression in gliomas.
Guanyu Wang   +11 more
doaj   +1 more source

Understanding the Multifaceted Role of Neutrophils in Cancer and Autoimmune Diseases

open access: yesFrontiers in Immunology, 2018
Neutrophils are one of the first immune cell types that are recruited to injury and infection site. As a vital component of the immune system, neutrophils are heterogeneous immune cells known to have phagocytic property and function in inflammation ...
Xu Wang   +14 more
doaj   +1 more source

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