Results 1 to 10 of about 530,516 (247)

Multiple Death Pathways of Neutrophils Regulate Alveolar Macrophage Proliferation

Cells, 2022
Alveolar macrophage (AM) proliferation and self-renewal play an important role in the lung tissue microenvironment. However, the impact of immune cells, especially the neutrophils, on AM homeostasis or function is not well characterized.
Xiaochen Gao, Weijia Zhang, Nan Zhang, Qing Yu, Jie Su, Ke Wang, Yanru Chen, Zhen F. Fu, Min Cui   +8 more
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Increased Circulating of CD54highCD181low Neutrophils in Myelodysplastic Syndrome

Frontiers in Oncology, 2021
Myelodysplastic syndromes (MDSs) are a group of heterogeneous hematopoietic stem/progenitor cells clonal diseases, characteristic features with myeloid dysplasia, leading to abnormality of neutrophils.
Liyan Yang, Hongzhao Li, Yumei Liu, Xinyan Xie, Huiqin Zhang, Haiyue Niu, Zonghong Shao, Limin Xing, Huaquan Wang   +8 more
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Antigen-Presenting Cell-Like Neutrophils Foster T Cell Response in Hyperlipidemic Patients and Atherosclerotic Mice

Frontiers in Immunology, 2022
Neutrophils constitute abundant cellular components in atherosclerotic plaques. Most of the current studies are focused on the roles of granular proteins released by neutrophils in atherosclerosis.
Tingrui Zhao, Tingrui Zhao, Tingrui Zhao, Qingsong Jiang, Qingsong Jiang, Qingsong Jiang, Wenming Li, Yin Wang, Yin Wang, Yin Wang, Yao Zou, Yao Zou, Yao Zou, Xinyu Chai, Xinyu Chai, Xinyu Chai, Zhiyi Yuan, Zhiyi Yuan, Zhiyi Yuan, Limei Ma, Limei Ma, Limei Ma, Ruihong Yu, Ruihong Yu, Ruihong Yu, Tao Deng, Chao Yu, Chao Yu, Chao Yu, Tingting Wang, Tingting Wang, Tingting Wang   +31 more
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Synovial fluid neutrophils in oligoarticular juvenile idiopathic arthritis have an altered phenotype and impaired effector functions

Arthritis Research & Therapy, 2021
Background Neutrophils are the most prevalent immune cells in the synovial fluid in inflamed joints of children with oligoarticular juvenile idiopathic arthritis (JIA).
Sabine Arve-Butler, Tobias Schmidt, Anki Mossberg, Elisabet Berthold, Birgitta Gullstrand, Anders A. Bengtsson, Fredrik Kahn, Robin Kahn   +7 more
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Mesenchymal stem cells shift the pro-inflammatory phenotype of neutrophils to ameliorate acute lung injury

Stem Cell Research & Therapy, 2023
Background Mesenchymal stem cell (MSC) treatment plays a major role in the management of acute lung injury (ALI), and neutrophils are the initial line of defense against ALI.
Bing Feng, Xudong Feng, Yingduo Yu, Haoying Xu, Qingqing Ye, Ruitian Hu, Xinru Fang, Feiqiong Gao, Jian Wu, Qiaoling Pan, Jiong Yu, Guanjing Lang, Lanjuan Li, Hongcui Cao   +13 more
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Neutrophils Lose the Capacity to Suppress T Cell Proliferation Upon Migration Towards Inflamed Joints in Juvenile Idiopathic Arthritis

Frontiers in Immunology, 2022
Neutrophils are highly abundant in synovial fluid of rheumatic inflamed joints. In oligoarticular juvenile idiopathic arthritis (JIA), synovial fluid neutrophils have impaired effector functions and altered phenotype.
Sabine Arve-Butler, Sabine Arve-Butler, Anki Mossberg, Anki Mossberg, Tobias Schmidt, Tobias Schmidt, Charlotte Welinder, Hong Yan, Elisabet Berthold, Elisabet Berthold, Petra Król, Robin Kahn, Robin Kahn   +12 more
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Understanding the Multifaceted Role of Neutrophils in Cancer and Autoimmune Diseases

Frontiers in Immunology, 2018
Neutrophils are one of the first immune cell types that are recruited to injury and infection site. As a vital component of the immune system, neutrophils are heterogeneous immune cells known to have phagocytic property and function in inflammation ...
Xu Wang, Xu Wang, Xu Wang, Xu Wang, Lin Qiu, Lin Qiu, Lin Qiu, Lin Qiu, Ziyi Li, Ziyi Li, Xiang-Yang Wang, Xiang-Yang Wang, Huanfa Yi, Huanfa Yi, Huanfa Yi   +14 more
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Neutrophils in COVID-19

Frontiers in Immunology, 2021
Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that neutrophils play an important role in the pathophysiology, particularly in those with severe disease courses.
Nico Reusch, Nico Reusch, Elena De Domenico, Elena De Domenico, Lorenzo Bonaguro, Lorenzo Bonaguro, Jonas Schulte-Schrepping, Jonas Schulte-Schrepping, Kevin Baßler, Kevin Baßler, Joachim L. Schultze, Joachim L. Schultze, Joachim L. Schultze, Anna C. Aschenbrenner, Anna C. Aschenbrenner, Anna C. Aschenbrenner, Anna C. Aschenbrenner   +16 more
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Neutrophils: New Critical Regulators of Glioma

Frontiers in Immunology, 2022
In cancer, neutrophils are an important part of the tumour microenvironment (TME). Previous studies have shown that circulating and infiltrating neutrophils are associated with malignant progression and immunosuppression in gliomas.
Guanyu Wang, Jinpeng Wang, Chaoshi Niu, Chaoshi Niu, Chaoshi Niu, Chaoshi Niu, Yan Zhao, Pengfei Wu, Pengfei Wu, Pengfei Wu, Pengfei Wu, Pengfei Wu   +11 more
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Comparison of Neutrophil Function in Granulocyte Concentrates From Prednisone- and G-CSF-Treated Donors: Effect of Stimulant, Leukapheresis and Storage

Frontiers in Medicine, 2022
Transfusion of granulocyte concentrates (GC) is an alternative therapy for neutropenic patients with life-threatening infections. While neutrophils are the main source of antimicrobial activity, only neutrophil numbers are used to certify GCs.
Andréa Murru, Andréa Murru, Andréa Murru, Marie-Ève Allard, Guillaume Paré, Guillaume Paré, Myriam Vaillancourt, Myriam Vaillancourt, Lucie Boyer, Marie-Pierre Cayer, Julien Vitry, Julien Vitry, Patricia Landry, Marie-Michèle Labrecque, Marie-Michèle Labrecque, Nancy Robitaille, Donald R. Branch, Mélissa Girard, Maria J. Fernandes, Maria J. Fernandes   +19 more
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