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Frontiers in Immunology, 2017 Neutrophils are the most abundant white blood cells and are the first recruited to inflammatory sites. Neutrophils are an important component of the tumor stroma and can exert both anti-tumoral and pro-tumoral activities, depending on their maturation ...
Matteo Massara +12 more
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Diagnostics, 2022 Although eosinophilic inflammation is characteristic of asthma pathogenesis, neutrophilic inflammation is also marked, and eosinophils and neutrophils can coexist in some cases. Based on the proportion of sputum cell differentiation, asthma is classified
Akira Yamasaki +2 more
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Neutrophils in Psoriasis [PDF]
Frontiers in Immunology, 2019 Neutrophils are the most abundant innate immune cells. The pathogenic roles of neutrophils are related to chronic inflammation and autoimmune diseases. Psoriasis is a chronic systemic inflammatory disease affecting ~2–3% of the world population.
Chih-Chao Chiang +15 more
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Candida albicans-stimulated hematopoietic stem and progenitor cells generate trained neutrophils with enhanced mitochondrial ROS production that defend against infection. [PDF]
PLoS PathogensCentral trained immunity, induced via reprogramming of hematopoietic stem and progenitor cells (HSPCs), mediates sustained heightened responsiveness of mature myeloid cells to secondary challenges.
María Sobén +4 more
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Frontiers in Immunology, 2019 Leprosy is an infectious disease caused by the intracellular bacillus Mycobacterium leprae that mainly affects the skin and peripheral nerves. One of the most intriguing aspects of leprosy is the diversity of its clinical forms.
Veronica Schmitz +7 more
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Frontiers in Immunology, 2018 Neutrophils are abundant in the circulation and are one of the immune system's first lines of defense against infection. There has been substantial work carried out investigating the role of neutrophils in malaria and it is clear that during infection ...
Elizabeth H. Aitken +2 more
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Frontiers in Immunology, 2021 Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that neutrophils play an important role in the pathophysiology, particularly in those with severe disease courses.
Nico Reusch +16 more
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Multiple Death Pathways of Neutrophils Regulate Alveolar Macrophage Proliferation
Cells, 2022 Alveolar macrophage (AM) proliferation and self-renewal play an important role in the lung tissue microenvironment. However, the impact of immune cells, especially the neutrophils, on AM homeostasis or function is not well characterized.
Xiaochen Gao +8 more
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Increased Circulating of CD54highCD181low Neutrophils in Myelodysplastic Syndrome
Frontiers in Oncology, 2021 Myelodysplastic syndromes (MDSs) are a group of heterogeneous hematopoietic stem/progenitor cells clonal diseases, characteristic features with myeloid dysplasia, leading to abnormality of neutrophils.
Liyan Yang +8 more
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